In vitro liquid-liquid phase separation induced by respiratory syncytial virus proteins and RNA.
V Basse, T Agarwal, T Sneideris, C-A Richard, J Troussier, J-J Vasseur, F Debart, J-F Eléouët, E de Csillery, T Knowles, M Galloux
Science advances
(2026)
12
Single-molecule detection methods and super-resolution imaging to study alpha-synuclein aggregation in post-mortem Parkinson’s disease brains
E Fertan, JSH Danial, S Neame, JYL Lam, MW Cotton, M Burke, Z Xia, Y Wu, B Powney, Y Imaizumi, A Quaegebeur, G Meisl, J Staddon, D Klenerman
Cell Rep Methods
(2026)
The role of N-terminal acetylation on biomolecular condensation
C G Oliveira, MTS Silva, E Kava, T Agarwal, G Cereghetti, E F Vicente, TPJ Knowles, AJ Costa-Filho, LFS Mendes
Commun Chem
(2026)
Spatially patterned, spectral single-molecule microscopy
JS Beckwith, B Cullinane, DF Heraghty, S Krokowski, CL Jones, S Yang, RC Gregory, RA Floto, AM Santos, SJ Davis, M Vendruscolo, D Klenerman, V Lindo, PK Sankaran, SF Lee
(2026)
Cortisol-resistant CAR-NK cells overcome steroid-induced immunosuppression in lung cancer
S Chakraborty, J Pramanik, G Alviter-Raymundo, CJ Ward, SK Shaji, Y Yamashita-Kanemaru, FAZ Ali, D Banik, Z Zhang, C Veiga-Villauriz, NZM Homer, J Simpson, S Laforest, S Tong, Q Zhao, J Roy, M Iqbal, AC Morris, MA Chapman, R Roychoudhuri, H Hussein, D Klenerman, K Saeb-Parsy, B Mahata
Signal transduction and targeted therapy
(2026)
11
A Correlative SICM-OPM Platform for Surface and Volumetric Imaging in Live Cells.
W Hong, Z Zhang, A Li, T Sun, Y Wu, DM Vadukul, D Jones, B Li, F Liu, FA Aprile, Y Korchev, J Gorelik, D Klenerman, A Shevchuk
Adv Sci (Weinh)
(2026)
Nucleation Kinetics Reveals a Distinct Biological Function Space of Biomolecular Condensates.
L-T Deck, SN Pacheco, H Ausserwöger, D Frenkel, NA Erkamp, TPJ Knowles
Advanced Science
(2026)
13
A swarm intelligence approach to density function reconstruction from moments using entropy optimization
P Biswas, SR Elliott
Proceedings of the National Academy of Sciences of the United States of America
(2026)
123
NPM1 Undergoes Salt-Dependent Reentrant Phase Separation Driven by IDR Conformational Plasticity and Electrostatic Crosstalk
Y Zhen, Y Tan, Y Tang, T Sneideris, H Ausserwöger, J Wen, TPJ Knowles, S Perrett, G Wei, S Wu
Small (Weinheim an der Bergstrasse, Germany)
(2026)
Discovery of first-in-class YTHDC1 small molecule inhibitors for the treatment of MYC-driven cancers
RC Centore, M Charles, M Arora, M Rebmann, MJ Rawling, J Cattin, X Yang, E Batchelor, M Watson, N Bharatham, A Howarth, S Qamar, L Andraghetti, A Seeber, MG Kharas, S Cohen, M Kulander, T Knowles, S Arora
Cancer Research
(2026)
86
Introducing Volatile Organic Compound Model Intercomparison Project (VOCMIP)
G Myhre, Ø Hodnebrog, S Krishnan, M Sand, M Sandstad, RB Skeie, L Clarisse, B Franco, DB Millet, KC Wells, A Archibald, HN Bryant, AT Chaudhri, DS Stevenson, D Hauglustaine, M Prather, JC Kaiser, DJL Olivie, M Schulz, O Wild, Y Wang, T Salameh, JE Williams, P Le Sager, F Paulot, K Tsigaridis, HE Plaas
Geoscientific Model Development
(2026)
19
Alzheimer's disease pathology degrades an NMDA receptor-dependent spontaneous activity pattern in cortico-hippocampal circuits.
R Ellingford, SS Harris, M Kehring, RM Rajani, FKW Lam, D Graykowski, D BÓ§ken, LA Welikovitch, A Khasnavis, R Laban, A Heslegrave, U Yaman, A Mate de Gerando, SA Bond, S Wray, DA Salih, D Dupret, RJ Dolan, D Klenerman, H Zetterberg, BT Hyman, MA Busche
Neuron
(2026)
Reversible peptide self-assembly enables sustained drug delivery with tuneable pharmacokinetics
TW Herling, J Wei, S Genapathy, C Rivera, M Persson, P Gennemark, D Workman, D Lundberg, E Bernard, H Bolt, MY Arteta, S Will, A Bak, D Hornigold, TPJ Knowles, ALG dos Santos
(2026)
Formation of S- and Z-twist supramolecular micro-ropes by peptide stereoisomers
H Yuan, Z Yang, C Yuan, S Shankar, A Levin, T Lv, Z Wang, W Sun, J Sitton, P-A Cazade, Y Dan, Y Tang, L Adler-Abramovich, Y Cao, S Rencus-Lazar, D Thompson, D Kurouski, TPJ Knowles, LJW Shimon, G Wei, B Xue, R Yang, E Gazit
Nature communications
(2026)
Chemical Softness as a Predictor for Reactivity at Metal Surfaces
AL Gunton, SJ Jenkins
Physical Chemistry Chemical Physics
(2026)
28
Tau catalyzes amyloid-β aggregation and toxicity in a polymorph-dependent manner
M Mosconi, C Leonardi, Z Armour-Garb, B Rocutto, M Beeg, G Meisl, L Ortigosa-Pascual, L Broggini, M Salmona, S Ricagno, TPJ Knowles, L Diomede
Proceedings of the National Academy of Sciences
(2026)
123
Evaluation of UKESM aerosol size and composition using ATom measurements indicates missing marine aerosol formation mechanisms
X-C He, NL Abraham, H Ding, MR Russo, DP Grosvenor, Y Ge, X Wang, AC Jones, P Campuzano-Jost, B Nault, A Kupc, D Blake, JL Jimenez, CJ Williamson, J Weber, AT Archibald, H Gordon
Atmospheric Chemistry and Physics
(2026)
26
Chemical composition differences in gas- and particle-phase organic and DMS-derived oxidation products between a pristine marine environment and a wildfire-influenced marine air mass
F Sari Doré, R Wu, E Matthews, C Wu, T Bannan, H Coe, A Archibald, M Hallquist
(2026)
Organic matter in dust-dominated aerosols over Namibia influenced by biomass burning and marine emissions
A Zherebker, C Baldo, P Formenti, C Giorio
(2026)
Reversibility and β-sheet formation are decoupled in tau condensate aging.
CM Fischer, IA Edu, T Šneideris, I Baronaite, Z Toprakcioglu, L-T Deck, D Qian, R Scrutton, L Dreyer, J Wen, DE Otzen, S Wu, S Perrett, TPJ Knowles
Proceedings of the National Academy of Sciences
(2026)
123
Determining the key sources of uncertainty in dimethyl sulfide and methanethiol oxidation under tropical, temperate, and polar marine conditions
LSD Jacob, BEH Harvey, C Giorio, AT Archibald
Atmospheric Chemistry and Physics (ACP)
(2026)
26
Toll-like receptor signalling outcome is determined by the stoichiometry of the endogenous TRIFosome
MC Moncrieffe, P Suresh, J Boyle, Y Cui, B Nawalpuri, B Verstak, YP Zhang, Z Zhang, M Taylor, EH Egelman, N Gay, D Klenerman, C Bryant
Science advances
(2026)
12
Constructing a single-objective oblique plane microscope (OPM) for fast, multi-colour, high-resolution volumetric fluorescence imaging
Z Zhang, W Hong, Y Wu, A Dey, A Shevchuk, D Klenerman
(2026)
Scaling Relations of Multicomponent Phase Coexistence Boundaries
D Qian, J Acker, RM Scrutton, CM Fischer, S Qamar, T Sneideris, A Borodavka, TPJ Knowles
Prx Life
(2026)
4
Charge-triggered switching mechanism in selenium selector enabling ultralow leakage current.
Y Sun, T Gotoh, J Zhao, M Zhang, S Shi, H Zhang, Z Liu, J Shen, R Dronskowski, Z Song, SR Elliott, M Zhu
Nat Mater
(2026)
25