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Yusuf Hamied Department of Chemistry

 

Recent Publications from the Physical Research Interest Group

PhaseXplorer Creates High-Dimensional Phase Diagrams with Closed-Loop Active Learning
SAH Jansen, LSA Dreyer, J van Basten, Y Yao, DE Otzen, TFA de Greef, TPJ Knowles, EW Meijer, NA Erkamp
– ACS Nano
(2025)
acsnano.5c07268
(DOI: 10.1021/acsnano.5c07268)
Tuning the morphology of aerosolised cellulose nanocrystal particulates via controlled aggregation
D Warnes, W Xu, JH Lim, RM Parker, B Frka-Petesic, R Freshwater, C Honorato-Rios, Y Ogawa, C Giorio, S Vignolini
– Carbohydrate Polymers
(2025)
124592
(DOI: 10.1016/j.carbpol.2025.124592)
Supplementary material to "Determining the key sources of uncertainty in dimethyl sulfide and methanethiol oxidation under tropical, temperate, and polar marine conditions"
LSD Jacob, BEH Harvey, C Giorio, AT Archibald
(2025)
(DOI: 10.5194/egusphere-2025-5103-supplement)
Determining the key sources of uncertainty in dimethyl sulfide and methanethiol oxidation under tropical, temperate, and polar marine conditions
LSD Jacob, BEH Harvey, C Giorio, AT Archibald
(2025)
(DOI: 10.5194/egusphere-2025-5103)
α-Synuclein driven cell susceptibility in Parkinson’s disease
S Lee, J Breiter, J Beckwith, E Brock, J Lachica, C Toomey, B Fu, M Ryten, L Weiss, N Wood, S Gandhi, M Vendruscolo
(2025)
(DOI: 10.21203/rs.3.rs-7375981/v1)
Beyond prion-like spreading in neurodegenerative disease
G Meisl, JB Rowe, D Klenerman
– Alzheimer's & Dementia
(2025)
21,
e70789
(DOI: 10.1002/alz.70789)
Multi-state Protein Design with DynamicMPNN
A Abrudan, SP Ojeda, CK Joshi, M Greenig, F Engelberger, A Khmelinskaia, J Meiler, M Vendruscolo, TPJ Knowles
(2025)
(DOI: 10.48550/arxiv.2507.21938)
Oxidative stress generated DNA damage by 6PPD and other tyre additives in A549 human lung epithelial cells
S Hyman, R Bilić, A Jensen, S Saladin, Y Tsybrii, O Nosko, D Topping, A Boies, C Giorio, M Roursgaard, P Møller
– Scientific Reports
(2025)
15,
35615
(DOI: 10.1038/s41598-025-19232-y)
Formation and composition of organic aerosols from the uptake of glyoxal on natural mineral dust aerosols: a laboratory study
F Battaglia, P Formenti, C Giorio, M Cazaunau, E Pangui, A Bergé, A Gratien, DL Pereira, T Bertin, JF de Brito, MN Romanias, V Michoud, C Baldo, S Chevaillier, G Noyalet, P Decorse, B Picquet-Varrault, J-F Doussin
– Atmospheric Chemistry and Physics
(2025)
25,
12409
(DOI: 10.5194/acp-25-12409-2025)
Large-scale visualisation of α-synuclein oligomers in Parkinson’s disease brain tissue
R Andrews, B Fu, CE Toomey, JC Breiter, J Lachica, JS Beckwith, R Tian, EE Brock, L-M Needham, GJ Chant, C Loiseau, A Deconfin, K Baspin, R Popovic, J Evans, Y Goh, B Kurt, L Senicar, M Edmonds, T Bartels, N Bengoa-Vergniory, PJ Magill, Z Jaunmuktane, OJ Freeman, BJM Taylor, J Hardy, T Lashley, M Ryten, M Vendruscolo, NW Wood, LE Weiss, S Gandhi, SF Lee
– Nat Biomed Eng
(2025)
1
(DOI: 10.1038/s41551-025-01496-4)
Nano-org, a functional resource for single-molecule localisation microscopy data.
S Shirgill, DJ Nieves, JA Pike, MA Ahmed, H Abbott, MHH Baragilly, K Savoye, JD Worboys, KS Hazime, E Bruggeman, A Garcia, DJ Williamson, P Rubin-Delanchy, R Peters, DM Davis, R Henriques, SF Lee, DM Owen
– Nature Communications
(2025)
16,
8674
(DOI: 10.1038/s41467-025-63674-x)
Nanoscale profiling of evolving intermolecular interactions in ageing FUS condensates
A Miller, Z Toprakcioglu, S Qamar, P St George-Hyslop, FS Ruggeri, T Knowles, M Vendruscolo
– Communications Chemistry
(2025)
8,
284
(DOI: 10.1038/s42004-025-01659-z)
Rare bioactive tau oligomers from Alzheimer brain support both templated misfolding and fibril formation
N Quittot, D Sivasankaran, D Boeken, Y Chen, JE Chun, A Wiedmer, V Derosla, MBMS Martins, FA Brooks, G Meisl, M Cotton, DG Arumuganainar, T Connors, A Melloni, M Frosch, D Oakley, L Makowski, M Wanunu, D Klenerman, BT Hyman
– bioRxiv
(2025)
2025.09.24.678227
(DOI: 10.1101/2025.09.24.678227)
Quantitative Profiling of Nanoscopic Protein Aggregates Reveals Specific Fingerprint of TDP-43-positive Assemblies in Motor Neuron Disease
D Cox, M Burke, S Milani, MA White, FM Waldron, D Böken, E Lobanova, J Sreedharan, JM Gregory, D Klenerman
– Advanced science (Weinheim, Baden-Wurttemberg, Germany)
(2025)
e05484
(DOI: 10.1002/advs.202505484)
Highly oxygenated molecules (HOMs) and secondary organic aerosol (SOA) formation from the oxidation of α- and β-phellandrenes by NO<sub>3</sub> radicals
S Harb, M Cirtog, S Alage, C Cantrell, M Cazaunau, V Michoud, E Pangui, A Bergé, C Giorio, F Battaglia, B Picquet-Varrault
– Atmospheric Chemistry and Physics
(2025)
25,
11003
(DOI: 10.5194/acp-25-11003-2025)
Optofluidic waveguides for the label-free study of silk protein aggregates
JR Heck, Z Toprakcioglu, TE Naegele, MH Frosz, TPJ Knowles, TG Euser
– ACS omega
(2025)
10,
46115
(DOI: 10.1021/acsomega.5c07826)
Neurodegeneration emerges at a cellular tipping point between aggregate accumulation and removal
MW Cotton, S Venkatesan, JS Beckwith, D Böken, CK Xu, JC Breiter, LE Berkowicz, LS Salazar, A Von Schulze, EA Andrzejewska, EE Brock, HL Han, MM Schneider, DD Sahtoe, D Baker, JB Rowe, A Goriely, WA McEwan, TPJ Knowles, SF Lee, R Halfmann, D Klenerman, G Meisl
(2025)
(DOI: 10.1101/2025.09.08.674880)
Secondary nucleation of α-Synuclein drives Mitochondria dysfunctions and Lewy body formation in Parkinson’s Disease
EE Prescott, J Wei, EF Garland, A Urbanek, F Capriglia, WH Molenkamp, DP Rhodes, L Heywood, A Schwartzentruber, E Stephen, R Hughes, O Bandmann, MO Collins, S Linse, A Abelein, J Johansson, M Vendruscolo, JR Highly, TPJ Knowles, H Mortiboys, S De
(2025)
(DOI: 10.1101/2025.09.17.676873)
Early synaptic pathology is associated with small tau aggregates in Alzheimer’s disease
E Fertan, S Kedia, G Meisl, MW Cotton, A Quaegebeur, MG Spillantini, D Klenerman
(2025)
(DOI: 10.1101/2025.09.13.676039)
Transcript Identification Using Arrayed Hydrogels With TrapFISH (Adv. Mater. Technol. 18/2025)
DB Morse, Z Toprakcioglu, A Denduluri‐Marthi, JD Brenton, CJ Thomas, TPJ Knowles
– Advanced Materials Technologies
(2025)
10,
e70330
(DOI: 10.1002/admt.70330)

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