Department of Chemistry

Current jobs in the Department of Chemistry at the University of Cambridge

Research Associate: Synthetic Chemist - Drug Discovery Against Protein-Protein Interactions (Fixed Term)

Fixed-term: The funds for this post are available to 31 January 2016 in the first instance, dependent on the achievement of project milestones to the satisfaction of the sponsor.

Applications are invited from PhD and post-doctoral chemists to join a multidisciplinary project funded by the Wellcome Trust, under the Seeding Drug Discovery Initiative, to develop small molecules that disrupt a specific protein-protein interaction. The project is a collaboration between the Departments of Chemistry (Prof. Chris Abell and Dr. John Skidmore), Biochemistry (Prof. Tom Blundell and Dr. Marko Hyvonen) and the Hutchison/MRC Research Centre (Prof. Ashok Venkitaraman and Dr. Grahame McKenzie).

The successful candidate will work as part of the chemistry team contributing to the design and synthesis of target molecules and the interpretation of screening and structural X-ray crystallographic data.

Applicants must have (or be about to obtain) a PhD in synthetic organic, medicinal or biological chemistry. They should have a proven track record exemplified by academic publications and/or industrial experience. Knowledge of medicinal chemistry and relevant post-doctoral experience would be advantageous. Applicants will be expected to work closely and interactively with colleagues in different disciplines, to have excellent communication skills, and the ability to work under pressure to meet deadlines.

This post is available immediately. Applications should include a CV, publications list, contact details for three professional referees and a completed CHRIS/6 form, Parts I and III only (downloadable from http://www.admin.cam.ac.uk/offices/hr/forms/chris6/), and should be sent to Dr. Katherine Abell, Department of Chemistry, Lensfield Road, Cambridge CB2 1EW (email: ka204@cam.ac.uk).

Please quote reference MA01806 on your application and in any correspondence about this vacancy.

The Department holds an Athena SWAN bronze award for women in Science, Technology, Engineering and Medicine.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

MA01806
£27,854-£36,298
30 October 2013
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Research Associate: Modelling the Effects of Bioactive Compound Mixtures Using Cheminformatics and Bioinformatics Approaches (Fixed Term)

Fixed-term: The funds for this post are available for 4 years in the first instance.

Applications are invited for a post-doctoral research associate to join the research group led by Dr Andreas Bender at the Unilever Centre for Molecular Science Informatics at the University of Cambridge on 1 February 2014 (or as soon as possible thereafter). The ERC-funded project will utilize cheminformatics and bioinformatics approaches for modelling the effect of mixtures of bioactive compounds, an area of importance both in the medical field (e.g. for combination treatments), as well as consumer safety (e.g. for toxicity modeling).

The research associate will be based at the Unilever Centre for Molecular Informatics (http://www-ucc.ch.cam.ac.uk/) in the Department of Chemistry, which is home to about 40 scientists in the cheminformatics and bioinformatics field. The research group which the successful candidate will be based in currently comprises about 15 scientists, and mixture modelling of compounds will be a future focus area of research for the group with another 3 project members to be recruited in the near future. The post-doctoral research associate to be recruited now represents an integral part of this project and will be able to (and is expected to) co-supervise other project members in the future.

Applicants should have (or be about to obtain) a relevant PhD in the fields of cheminformatics, bioinformatics, scientific data analysis, machine learning, or related fields. Expertise in the areas of scientific programming (e.g. in Python, Perl, C, Java, etc.), handling chemical and biological information in databases, and data mining and analysis packages (such as R) are essential for the post, as is a general understanding of chemical and biological information. Previous experience in the analysis of bioactivity data (such as conventional high-throughput screening data) or biological readouts (e.g. from high-content screens, or transcriptomics) would be highly advantageous, as is previous demonstrated successful experience in leading projects and working in interdisciplinary teams.

For informal enquiries, please contact Dr Andreas Bender (email: ab454@cam.ac.uk).

Applications should include a CV, publications list, contact details for three professional referees and a completed CHRIS/6 form, Parts I and III only (downloadable from http://www.admin.cam.ac.uk/offices/hr/forms/chris6/), and should be sent to Susan Begg, Department of Chemistry, Lensfield Road, Cambridge CB2 1EW (email: smb28@cam.ac.uk).

Please quote reference MA01849 on your application and in any correspondence about this vacancy.

The Department holds an Athena SWAN bronze award for women in Science, Technology, Engineering and Medicine.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

MA01849
£27,854-£36,298
8 November 2013
Click here for more information

Previously available jobs can be seen here