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Recent Publications from the Synthesis Research Interest Group

Controlled membrane translocation provides a mechanism for signal transduction and amplification
MJ Langton, F Keymeulen, M Ciaccia, NH Williams, CA Hunter
– Nature Chemistry
(2016)
9,
426
Selective C70 encapsulation by a robust octameric nanospheroid held together by 48 cooperative hydrogen bonds.
G Markiewicz, A Jenczak, M Kołodziejski, JJ Holstein, JKM Sanders, AR Stefankiewicz
– Nature Communications
(2017)
8,
15109
H-Bond Acceptor Parameters for Anions.
SJ Pike, JJ Hutchinson, CA Hunter
– Journal of the American Chemical Society
(2017)
139,
6700
H-Bond Self-Assembly: Folding versus Duplex Formation.
D Núñez-Villanueva, G Iadevaia, AE Stross, MA Jinks, JA Swain, CA Hunter
– Journal of the American Chemical Society
(2017)
139,
6654
Enhanced Chelate Cooperativity in Polar Solvents.
S Henkel, MC Misuraca, Y Ding, M Guitet, CA Hunter
– Journal of the American Chemical Society
(2017)
139,
6675
Zampanolide, a Microtubule-Stabilizing Agent, Is Active in Resistant Cancer Cells and Inhibits Cell Migration.
JJ Field, PT Northcote, I Paterson, K-H Altmann, JF Díaz, JH Miller
– International journal of molecular sciences
(2017)
18,
Recognition-Controlled Membrane Translocation for Signal Transduction across Lipid Bilayers.
MJ Langton, NH Williams, CA Hunter
– Journal of the American Chemical Society
(2017)
139,
6461
Protein modification via alkyne hydrosilylation using a substoichiometric amount of ruthenium( ii ) catalyst
TT-L Kwan, O Boutureira, EC Frye, SJ Walsh, MK Gupta, S Wallace, Y Wu, F Zhang, HF Sore, WRJD Galloway, JW Chin, M Welch, GJL Bernardes, DR Spring
– Chem. Sci.
(2017)
8,
3871
A fragment-based approach leading to the discovery of a novel binding site and the selective CK2 inhibitor CAM4066.
C De Fusco, P Brear, J Iegre, KH Georgiou, HF Sore, M Hyvönen, DR Spring
– Bioorganic & medicinal chemistry
(2016)
A possible extension to the RInChI as a means of providing machine readable process data
PM Jacob, T Lan, JM Goodman, AA Lapkin
– Journal of Cheminformatics
(2017)
9,
ARTN 23
Utilization of flow chemistry in catalysis: New avenues for the selective synthesis of Bis(indolyl)methanes
SS Mohapatra, ZE Wilson, S Roy, SV Ley
– Tetrahedron
(2017)
73,
1812
A surface site interaction point methodology for macromolecules and huge molecular databases.
A Oliver, CA Hunter, R Prohens, JL Rosselló
– Journal of Computational Chemistry
(2017)
38,
419
One-Pot Acid-Catalyzed Ring-Opening/Cyclization/Oxidation of Aziridines with N -Tosylhydrazones: Access to 1,2,4-Triazines
L Crespin, L Biancalana, T Morack, DC Blakemore, SV Ley
– Organic Letters
(2017)
19,
1084
Stereocontrolled semi-syntheses of deguelin and tephrosin
DA Russell, JJ Freudenreich, JJ Ciardiello, HF Sore, DR Spring
– Org Biomol Chem
(2017)
15,
1593
(Z)-selective Takai olefination of salicylaldehydes
SM Geddis, CE Hagerman, WRJD Galloway, HF Sore, JM Goodman, DR Spring
– Beilstein journal of organic chemistry
(2017)
13,
323
Macrocyclized Extended Peptides: Inhibiting the Substrate-Recognition Domain of Tankyrase
W Xu, YH Lau, G Fischer, YS Tan, A Chattopadhyay, M de la Roche, M Hyvönen, C Verma, DR Spring, LS Itzhaki
– Journal of the American Chemical Society
(2017)
139,
2245
Ion-Pair-Directed meta-Selective C–H Borylation of Aromatic Quaternary Ammonium Salts
MT Mihai, RJ Phipps
– Synlett
(2017)
28,
Continuous flow hydration of pyrazine-2-carbonitrile in a manganese dioxide column reactor
C Battilocchio, SH Lau, JM Hawkins, SV Ley
– Organic Syntheses
(2017)
94,
34
Rapid Asymmetric Synthesis of Disubstituted Allenes by Coupling of Flow-Generated Diazo Compounds and Propargylated Amines
J-S Poh, S Makai, T von Keutz, DN Tran, C Battilocchio, P Pasau, SV Ley
– Angewandte Chemie
(2017)
129,
1890
Rapid Asymmetric Synthesis of Disubstituted Allenes by Coupling of Flow-Generated Diazo Compounds and Propargylated Amines
J-S Poh, S Makai, T von Keutz, DN Tran, C Battilocchio, P Pasau, SV Ley
– Angewandte Chemie International Edition (English)
(2017)
56,
1864