skip to content
 

Dr Gonçalo Bernardes

Portrait of gb453

 

Our research programme is at the interfaces of Chemistry and Biology. It aims at developing novel aqueous, chemoselective methods and their use for selective protein/ligand labelling in vitro and in vivo to understand and influence human disease. For further info on our research and for oportunities please check our research group website.

 

Publications

Frontispiece: Site-Selective Modification of Proteins with Oxetanes
O Boutureira, N Martínez-Sáez, KM Brindle, AA Neves, F Corzana, GJL Bernardes
– Chemistry - A European Journal
(2017)
23,
A brain-sparing diphtheria toxin for chemical genetic ablation of peripheral cell lineages
MMA Pereira, I Mahú, E Seixas, N Martinéz-Sánchez, N Kubasova, RM Pirzgalska, P Cohen, MO Dietrich, M López, GJL Bernardes, AI Domingos
– Nature Communications
(2017)
8,
14967
Site-Selective Modification of Proteins with Oxetanes.
O Boutureira, N Martínez-Sáez, KM Brindle, AA Neves, F Corzana, GJL Bernardes
– Chemistry
(2017)
Site-selective installation of BASHY fluorescent dyes to Annexin V for targeted detection of apoptotic cells
PMSD Cal, F Sieglitz, FMF Santos, C Parente Carvalho, A Guerreiro, JB Bertoldo, U Pischel, PMP Gois, GJL Bernardes
– Chemical communications (Cambridge, England)
(2016)
53,
368
Vinyl Ether/Tetrazine Pair for the Traceless Release of Alcohols in Cells.
E Jiménez-Moreno, Z Guo, BL Oliveira, IS Albuquerque, A Kitowski, A Guerreiro, O Boutureira, T Rodrigues, G Jiménez-Osés, GJL Bernardes
– Angew Chem Int Ed Engl
(2017)
56,
243
Vinyl Ether/Tetrazine Pair for the Traceless Release of Alcohols in Cells
E Jiménez-Moreno, Z Guo, BL Oliveira, IS Albuquerque, A Kitowski, A Guerreiro, O Boutureira, T Rodrigues, G Jiménez-Osés, GJL Bernardes
– Angewandte Chemie
(2017)
129,
249
Trends in therapeutic drug conjugates for bacterial diseases: a patent review
PMSD Cal, MJ Matos, GJL Bernardes
– Expert Opin Ther Pat
(2016)
27,
1
Antibody-drug conjugates: The missing link.
T Rodrigues, GJL Bernardes
– Nature Chemistry
(2016)
8,
1088
A Minimal, Unstrained S-Allyl Handle for Pre-Targeting Diels–Alder Bioorthogonal Labeling in Live Cells
BL Oliveira, Z Guo, O Boutureira, A Guerreiro, G Jiménez-Osés, GJL Bernardes
– Angew Chem Int Ed Engl
(2016)
55,
14683
Stoichiometric and irreversible cysteine-selective protein modification using carbonylacrylic reagents
B Bernardim, PMSD Cal, MJ Matos, BL Oliveira, N Martínez-Sáez, IS Albuquerque, E Perkins, F Corzana, ACB Burtoloso, G Jiménez-Osés, GJL Bernardes
– Nature Communications
(2016)
7,
13128
  •  
  • 1 of 9
  • >

Research Group

Research Interest Groups

Telephone number

01223 336305

Email address

gb453@cam.ac.uk

College

Peterhouse