Department of Chemistry

portrait of Dr Goncalo Bernardes

Dr Goncalo Bernardes

Groups: Bernardes group website

Telephone: 01223 336305

E-mail: gb453@cam.ac.uk

 

 


General


Our research programme is at the interfaces of Chemistry and Biology. It aims at developing novel aqueous, chemoselective methods and their use for selective protein/ligand labelling in vitro and in vivo to understand and influence human disease. For further info on our research and for oportunities please check our research group website.

Research Interests


Teaching


Personal


Funding


External Links 

Publications

Synthetically defined glycoprotein vaccines: current status and future directions
R Adamo, A Nilo, B Castagner, O Boutureira, F Berti, GJL Bernardes - Chemical Science (2013) 4, 2995
(DOI: 10.1039/c3sc50862e)
Spacer length shapes drug release and therapeutic efficacy of traceless disulfide-linked ADCs targeting the tumor neovasculature
M Steiner, I Hartmann, E Perrino, G Casi, S Brighton, I Jelesarov, GJL Bernardes, D Neri - Chemical Science (2013) 4, 297
(DOI: 10.1039/C2SC21107F)
Highlights from the 48th EUCHEM conference on stereochemistry, Bürgenstock, Switzerland, May 2013
GJL Bernardes - Chemical Communications (2013) 49, 8578
(DOI: 10.1039/c3cc90259e)
Generation of carbon monoxide releasing molecules (CO-RMs) as drug candidates for the treatment of acute liver injury: Targeting of CO-RMs to the liver
AR Marques, L Kromer, DJ Gallo, N Penacho, SS Rodrigues, JD Seixas, GJL Bernardes, PM Reis, SL Otterbein, RA Ruggieri, ASG Gonçalves, AML Gonçalves, MND Matos, I Bento, LE Otterbein, WA Blättler, CC Romão - Organometallics (2012) 31, 5810
(DOI: 10.1021/om300360c)
A novel carbon monoxide-releasing molecule fully protects mice from severe malaria
AC Pena, N Penacho, L Mancio-Silva, R Neres, JD Seixas, AC Fernandes, CC Romão, MM Mota, GJL Bernardes, A Pamplona - Antimicrobial Agents and Chemotherapy (2012) 56, 1281
(DOI: 10.1128/AAC.05571-11)
Selenenylsulfide-linked homogeneous glycopeptides and glycoproteins: Synthesis of human "hepatic Se MetaboliteA"
O Boutureira, GJL Bernardes, M Fernández-González, DC Anthony, BG Davis - Angew Chem Int Ed Engl (2012) 51, 1432
(DOI: 10.1002/anie.201106658)
A traceless vascular-targeting antibody-drug conjugate for cancer therapy
GJL Bernardes, G Casi, S Trüssel, I Hartmann, K Schwager, J Scheuermann, D Neri - Angewandte Chemie - International Edition (2012) 51, 941
(DOI: 10.1002/anie.201106527)
Fucose-specific conjugation of hydrazide derivatives to a vascular-targeting monoclonal antibody in IgG format
K Zuberbühler, G Casi, GJL Bernardes, D Neri - Chemical Communications (2012) 48, 7100
Developing drug molecules for therapy with carbon monoxide
CC Romão, WA Blättler, JD Seixas, GJL Bernardes - Chemical Society Reviews (2012) 41, 3571
Direct radiolabelling of proteins at cysteine using [F-18]-fluorosugars
O Boutureira, GJL Bernardes, F D'Hooge, BG Davis - Chemical Communications (2011) 47, 10010
(DOI: 10.1039/c1cc13524d)