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Dr Gonçalo Bernardes

Portrait of gb453

 

Our research programme is at the interfaces of Chemistry and Biology. It aims at developing novel aqueous, chemoselective methods and their use for selective protein/ligand labelling in vitro and in vivo to understand and influence human disease. For further info on our research and for oportunities please check our research group website.

 

Publications

Site-selective protein-modification chemistry for basic biology and drug development
N Krall, FP da Cruz, O Boutureira, GJ Bernardes – Nature Chemistry (2016) 8, 103
Urban Endocrine Disruptors Targeting Breast Cancer Proteins
D Montes-Grajales, GJ Bernardes, J Olivero-Verbel – Chemical research in toxicology (2016) 29, 150
Construction of homogeneous antibody-drug conjugates using site-selective protein chemistry
P Akkapeddi, SA Azizi, AM Freedy, PMSD Cal, PMP Gois, GJL Bernardes – Chem. Sci. (2016) 7, 2954
Enhancing Methotrexate Tolerance with Folate Tagged Liposomes in Arthritic Mice
E Nogueira, F Lager, D Le Roux, P Nogueira, J Freitas, C Charvet, G Renault, A Loureiro, CR Almeida, A Ohradanova-Repic, C Machacek, GJ Bernardes, A Moreira, H Stockinger, M Burnet, AM Carmo, AC Gomes, A Preto, G Bismuth, A Cavaco-Paulo – Journal of Biomedical Nanotechnology (2015) 11, 2243
Sulfur-Limonene Polysulfide: A Material Synthesized Entirely from Industrial By-Products and Its Use in Removing Toxic Metals from Water and Soil
MP Crockett, AM Evans, MJ Worthington, IS Albuquerque, AD Slattery, CT Gibson, JA Campbell, DA Lewis, GJ Bernardes, JM Chalker – Angew Chem Int Ed Engl (2015) 55, 1714
Peptide Anchor for Folate-Targeted Liposomal Delivery
E Nogueira, IC Mangialavori, A Loureiro, NG Azoia, MP Sárria, P Nogueira, J Freitas, J Härmark, U Shimanovich, A Rollett, G Lacroix, GJ Bernardes, G Guebitz, H Hebert, A Moreira, AM Carmo, JP Rossi, AC Gomes, A Preto, A Cavaco-Paulo – Biomacromolecules (2015) 16, 2904
Deciphering the Non-Equivalence of Serine and Threonine O-Glycosylation Points: Implications for Molecular Recognition of the Tn Antigen by an anti-MUC1 Antibody
N Martínez-Sáez, J Castro-Lõpez, J Valero-González, D Madariaga, I Compañõn, VJ Somovilla, M Salvadõ, JL Asensio, J Jiménez-Barbero, A Avenoza, JH Busto, GJL Bernardes, JM Peregrina, R Hurtado-Guerrero, F Corzana – Angewandte Chemie - International Edition (2015) 54, 9830
Size controlled protein nanoemulsions for active targeting of folate receptor positive cells
A Loureiro, E Nogueira, NG Azoia, MP Sárria, AS Abreu, U Shimanovich, A Rollett, J Härmark, H Hebert, G Guebitz, GJ Bernardes, A Preto, AC Gomes, A Cavaco-Paulo – Colloids and surfaces. B, Biointerfaces (2015) 135, 90
Deciphering the Non-Equivalence of Serine and Threonine O-Glycosylation Points: Implications for Molecular Recognition of the Tn Antigen by an anti-MUC1 Antibody.
N Martínez-Sáez, J Castro-López, J Valero-González, D Madariaga, I Compañón, VJ Somovilla, M Salvadó, JL Asensio, J Jiménez-Barbero, A Avenoza, JH Busto, GJ Bernardes, JM Peregrina, R Hurtado-Guerrero, F Corzana – Angew Chem Int Ed Engl (2015) 54, 9830
Synthesis of fluorosugar reagents for the construction of well-defined fluoroglycoproteins
M Salvadó, B Amgarten, S Castillón, GJ Bernardes, O Boutureira – Organic Letters (2015) 17, 2836
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Research Interest Groups

Telephone number

01223 336305

Email address

gb453@cam.ac.uk

College

Peterhouse