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Dr Andrew Bond

Chemical Crystallography

Crystallographic methods provide detailed atomic-level descriptions of crystalline solids, including molecular structure and geometrical information on intermolecular interactions.

Single-crystal and powder X-ray diffraction are core analytical techniques within the chemical sciences, which support and augment a broad range of research within the Department. Modern diffraction instruments, applied at both laboratory and synchrotron sources, enable ever more complex chemical problems to be tackled using crystallographic methods: for example, characterizing and understanding the consequences of disorder in molecular crystals or monitoring chemical changes in single crystals or crystalline powders.

An area of specific interest is the pharmaceutical sciences, where there is a need to understand and control the occurrence and properties of crystalline and amorphous molecular solids during production and formulation of medicinal products.



Zn(II) mediates vancomycin polymerization and potentiates its antibiotic activity against resistant bacteria.
A Zarkan, H-R Macklyne, DY Chirgadze, AD Bond, AR Hesketh, H-J Hong
– Scientific reports
Dehydration of Nitrofurantoin Monohydrate during Melt Extrusion
D Raijada, L Arnfast, AD Bond, J Aho, J Bøtker, N Sandler, J Rantanen
– Crystal Growth & Design
Unearthing a sesterterpene biosynthetic repertoire in the Brassicaceae through genome mining reveals convergent evolution.
AC Huang, SA Kautsar, YJ Hong, MH Medema, AD Bond, DJ Tantillo, A Osbourn
– Proceedings of the National Academy of Sciences of the United States of America
Downstream Processability of Crystal Habit-Modified Active Pharmaceutical Ingredient
N Pudasaini, PP Upadhyay, CR Parker, SU Hagen, AD Bond, J Rantanen
– Organic Process Research and Development
A Modular Approach to Inorganic Phosphazane Macrocycles.
AJ Plajer, R García-Rodríguez, CGM Benson, PD Matthews, AD Bond, S Singh, LH Gade, DS Wright
– Angew Chem Int Ed Engl
A new and potentially prebiotic α-cytidine derivative
M Tsanakopoulou, J Xu, AD Bond, JD Sutherland
– Chemical communications (Cambridge, England)
A non-chiral lithium aluminate reagent for the determination of enantiomeric excess of chiral alcohols
R García-Rodríguez, S Hanf, AD Bond, DS Wright
– Chemical communications (Cambridge, England)
A Modular Approach to Inorganic Phosphazane Macrocycles
AJ Plajer, R García-Rodríguez, CGM Benson, PD Matthews, AD Bond, S Singh, LH Gade, DS Wright
– Angewandte Chemie
Multidentate 2-pyridyl-phosphine ligands - towards ligand tuning and chirality.
S Hanf, R García-Rodríguez, S Feldmann, AD Bond, E Hey-Hawkins, DS Wright
– Dalton transactions (Cambridge, England : 2003)
A versatile hard–soft N/S-ligand for metal coordination and cluster formation
CGM Benson, AJ Plajer, R García-Rodríguez, AD Bond, S Singh, LH Gade, DS Wright
– Chemical communications (Cambridge, England)
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Research Group

Telephone number

01223 336352
01223 762015

Email address