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  • Currently displaying 22001 - 22020 of 29639 publications
Author(s)
Publication title
Journal Name
Publication year
Pharmacophoric pattern matching in files of three-dimensional chemical structures: Comparison of conformational-searching algorithms for flexible searching
DE Clark, G Jones, P Willett, PW Kenny, RC Glen
Journal of Chemical Information and Computer Sciences
(2002)
34
MATCHING 2-DIMENSIONAL CHEMICAL GRAPHS USING GENETIC ALGORITHMS
RD Brown, G Jones, P Willett, RC Glen
Journal of Chemical Information and Computer Sciences
(2002)
34
The development of versions 3 and 4 of the Cambridge Structural Database System
FH Allen, JE Davies, JJ Galloy, O Johnson, O Kennard, CF Macrae, EM Mitchell, GF Mitchell, JM Smith, DG Watson
Journal of Chemical Information and Modeling
(2002)
31
Acetoacetate Decarboxylase. Identification of Lysine at the Active Site
S Warren, B Zerner, FH Westheimer
Biochemistry
(2002)
5
Anomalous pH dependence of kcat-KM in enzyme reactions. Rate constants for the association of chymotrypsin with substrates.
M Renard, AR Fersht
Biochemistry
(2002)
12
Leaving group specificity in the chymotrypsin-catalyzed hydrolysis of peptides. A stereochemical interpretation.
AR Fersht, DM Blow, J Fastrez
Biochemistry
(2002)
12
Demonstration of the acyl-enzyme mechanism for the hydrolysis of peptides and anilides by chymotrypsin.
J Fastrez, AR Fersht
Biochemistry
(2002)
12
Mechanism of chymotrypsin. Structure, reactivity, and nonproductive binding relationships.
J Fastrez, AR Fersht
Biochemistry
(2002)
12
INFLUENCE OF GLOBIN STRUCTURE ON STATE OF HEME .2. ALLOSTERIC TRANSITIONS IN METHEMOGLOBIN
MF Perutz, AR Fersht, SR Simon, GC Roberts
Biochemistry
(2002)
13
pH dependence of chymotrypsin catalysis. Appendix: substrate binding to dimeric alpha-chymotrypsin studied by x-ray diffraction and the equilibrium method.
AR Fersht, M Renard
Biochemistry
(2002)
13
Comments on the proposed rigidity of staphylococcal protease.
CM Dobson
Biochemistry
(2002)
14
Tyrosyl-tRNA synthetase from Escherichia coli. Stoichiometry of ligand binding and half-of-the-sites reactivity in aminoacylation.
R Jakes, AR Fersht
Biochemistry
(2002)
14
Ligand binding and enzymic catalysis coupled through subunits in tyrosyl-tRNA synthetase.
AR Fersht, RS Mulvey, GL Koch
Biochemistry
(2002)
14
DEMONSTRATION OF 2 ACTIVE-SITES ON A MONOMERIC AMINOACYL-TRANSFER-RNA SYNTHETASE - POSSIBLE ROLES OF NEGATIVE COOPERATIVITY AND HALF-OF-SITES REACTIVITY IN OLIGOMERIC ENZYMES
AR Fersht
Biochemistry
(2002)
14
Active site titration and aminoacyl adenylate binding stoichiometry of aminoacyl-tRNA synthetases
AR Fersht, JS Ashford, CJ Bruton, R Jakes, GL Koch, BS Hartley
Biochemistry
(2002)
14
Enzyme hyperspecificity. Rejection of threonine by the valyl-tRNA synthetase by misacylation and hydrolytic editing.
AR Fersht, MM Kaethner
Biochemistry
(2002)
15
Ligand binding stoichiometries, subunit structure, and slow transitions in aminoacyl-tRNA synthetases
RS Mulvey, AR Fersht
Biochemistry
(2002)
16
Mechanism of aminoacylation of transfer RNA. A pre-steady-state analysis of the reaction pathway catalyzed by the methionyl-tRNA synthetase of Bacillus stearothermophilus
RS Mulvey, AR Fersht
Biochemistry
(2002)
17
Interactions between the quaternary structure of the globin and the spin state of the heme in ferric mixed spin derivatives of hemoglobin
MF Perutz, JK Sanders, DH Chenery, RW Noble, RR Pennelly, LW Fung, C Ho, I Giannini, D Pörschke, H Winkler
Biochemistry
(2002)
17
Evidence for the double-sieve editing mechanism in protein synthesis. Steric exclusion of isoleucine by valyl-tRNA synthetases
AR Fersht, C Dingwall
Biochemistry
(2002)
18