Yusuf Hamied Department of Chemistry

Publications by Professor Steve Ley CBE FRS FMedSci

The application of a monolithic triphenylphosphine reagent for conducting Ramirez gem-dibromoolefination reactions in flow
KA Roper, MB Berry, SV Ley
Beilstein J Org Chem
(2013)
9
(doi: 10.3762/bjoc.9.207)
Scaling up of continuous flow processes with gases using a tube-in-tube reactor: Inline titrations and fanetizole synthesis with ammonia
JC Pastre, DL Browne, M O’Brien, SV Ley
Organic Process Research and Development
(2013)
17
(doi: 10.1021/op400152r)
The rapid generation of isothiocyanates in flow.
M Baumann, IR Baxendale
Beilstein journal of organic chemistry
(2013)
9
(doi: 10.3762/bjoc.9.184)
The synthesis of neurotensin antagonist SR 48692 for prostate cancer research
IR Baxendale, S Cheung, MO Kitching, SV Ley, JW Shearman
Bioorganic and Medicinal Chemistry
(2013)
21
(doi: 10.1016/j.bmc.2013.04.075)
A Continuous Flow Solution to Achieving Efficient Aerobic Anti-Markovnikov Wacker Oxidation
SL Bourne, SV Ley
Advanced Synthesis & Catalysis
(2013)
355
(doi: 10.1002/adsc.201300278)
Flow Synthesis and Biological Studies of an Analgesic Adamantane Derivative That Inhibits P2X7-Evoked Glutamate Release.
C Battilocchio, L Guetzoyan, C Cervetto, L Di Cesare Mannelli, D Frattaroli, IR Baxendale, G Maura, A Rossi, L Sautebin, M Biava, C Ghelardini, M Marcoli, SV Ley
ACS Medicinal Chemistry Letters
(2013)
4
(doi: 10.1021/ml400079h)
Camera-enabled techniques for organic synthesis.
SV Ley, RJ Ingham, M O'Brien, DL Browne
Beilstein journal of organic chemistry
(2013)
9
(doi: 10.3762/bjoc.9.118)
Flow chemistry approaches directed at improving chemical synthesis
IR Baxendale, L Brocken, CJ Mallia
Green Processing and Synthesis
(2013)
2
(doi: 10.1515/gps-2013-0029)
Studies of a diastereoselective electrophilic fluorination reaction employing a cryo-flow reactor
S Ley, K Nakayama, D Browne, I Baxendale
Synlett
(2013)
24
(doi: 10.1055/s-0033-1338455)
A Machine‐Assisted Flow Synthesis of SR48692: A Probe for the Investigation of Neurotensin Receptor‐1
C Battilocchio, BJ Deadman, N Nikbin, MO Kitching, IR Baxendale, SV Ley
Chemistry – A European Journal
(2013)
19
(doi: 10.1002/chem.201300696)
A mild and efficient flow procedure for the transfer hydrogenation of ketones and aldehydes using hydrous zirconia
C Battilocchio, JM Hawkins, SV Ley
Organic Letters
(2013)
15
(doi: 10.1021/ol400856g)
Continuous Cold without Cryogenic Consumables: Development of a Convenient Laboratory Tool for Low‐Temperature Flow Processes
DL Browne, BH Harji, SV Ley
Chemical Engineering & Technology
(2013)
36
(doi: 10.1002/ceat.201200581)
Synthesis of spongistatin 2 employing a new route to the EF fragment
H Kraus, A Français, M O'Brien, J Frost, A Diéguez-Vázquez, A Polara, N Baricordi, R Horan, D-S Hsu, T Tsunoda, SV Ley
Chemical Science
(2013)
4
(doi: 10.1039/c3sc50304f)
The integration of flow reactors into synthetic organic chemistry
IR Baxendale
Journal of Chemical Technology & Biotechnology
(2013)
88
(doi: 10.1002/jctb.4012)
Synthesis of (-)-hennoxazole A: Integrating batch and flow chemistry methods
A Fernández, ZG Levine, M Baumann, S Sulzer-Mossé, C Sparr, S Schläger, A Metzger, IR Baxendale, SV Ley
Synlett
(2013)
24
(doi: 10.1055/s-0032-1318109)
A prototype device for evaporation in batch and flow chemical processes
BJ Deadman, C Battilocchio, E Sliwinski, SV Ley
Green Chemistry
(2013)
15
(doi: 10.1039/c3gc40967h)
Flow chemistry synthesis of zolpidem, alpidem and other GABAAagonists and their biological evaluation through the use of in-line frontal affinity chromatography
L Guetzoyan, N Nikbin, IR Baxendale, SV Ley
Chem. Sci.
(2013)
4
(doi: 10.1039/c2sc21850j)
A Continuous Flow Solution to Achieving Efficient Aerobic Anti-Markovnikov Wacker Oxidation
SL Bourne, SV Ley
Advanced Synthesis and Catalysis
(2013)
342
Flow Chemistry Syntheses of Styrenes, Unsymmetrical Stilbenes and Branched Aldehydes
SL Bourne, M O'Brien, S Kasinathan, P Koos, P Tolstoy, DX Hu, RW Bates, B Martin, B Schenkel, SV Ley
Chemcatchem
(2012)
5
(doi: 10.1002/cctc.201200778)
The synthesis of Bcr-Abl inhibiting anticancer pharmaceutical agents imatinib, nilotinib and dasatinib
BJ Deadman, MD Hopkin, IR Baxendale, SV Ley
Organic & Biomolecular Chemistry
(2012)
11
(doi: 10.1039/c2ob27003j)
Yusuf Hamied Department of Chemistry
Lensfield Road
Cambridge
CB2 1EW
T: +44 (0) 1223 336300
enquiries@ch.cam.ac.uk
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