Yusuf Hamied Department of Chemistry

Publications by Professor Steve Ley CBE FRS FMedSci

The synthesis of neurotensin antagonist SR 48692 for prostate cancer research
IR Baxendale, S Cheung, MO Kitching, SV Ley, JW Shearman
Bioorganic and Medicinal Chemistry
(2013)
21
(doi: 10.1016/j.bmc.2013.04.075)
A Continuous Flow Solution to Achieving Efficient Aerobic Anti‐Markovnikov Wacker Oxidation
SL Bourne, SV Ley
Advanced Synthesis & Catalysis
(2013)
355
(doi: 10.1002/adsc.201300278)
Flow synthesis and biological studies of an analgesic adamantane derivative that inhibits P2X7-evoked glutamate release
C Battilocchio, L Guetzoyan, C Cervetto, L Di Cesare Mannelli, D Frattaroli, IR Baxendale, G Maura, A Rossi, L Sautebin, M Biava, C Ghelardini, M Marcoli, SV Ley
ACS Medicinal Chemistry Letters
(2013)
4
(doi: 10.1021/ml400079h)
Camera-enabled techniques for organic synthesis
SV Ley, RJ Ingham, M O'Brien, DL Browne
Beilstein Journal of Organic Chemistry
(2013)
9
(doi: 10.3762/bjoc.9.118)
Flow chemistry approaches directed at improving chemical synthesis
IR Baxendale, L Brocken, CJ Mallia
gps
(2013)
2
(doi: 10.1515/gps-2013-0029)
Studies of a Diastereoselective Electrophilic Fluorination Reaction Employing a Cryo-Flow Reactor
S Ley, K Nakayama, D Browne, I Baxendale
Synlett
(2013)
24
(doi: 10.1055/s-0033-1338455)
A mild and efficient flow procedure for the transfer hydrogenation of ketones and aldehydes using hydrous zirconia
C Battilocchio, JM Hawkins, SV Ley
Organic Letters
(2013)
15
(doi: 10.1021/ol400856g)
A Machine-Assisted Flow Synthesis of SR48692: A Probe for the Investigation of Neurotensin Receptor-1
C Battilocchio, BJ Deadman, N Nikbin, MO Kitching, IR Baxendale, SV Ley
Chemistry – A European Journal
(2013)
19
(doi: 10.1002/chem.201300696)
Continuous Cold without Cryogenic Consumables: Development of a Convenient Laboratory Tool for Low-Temperature Flow Processes
DL Browne, BH Harji, SV Ley
Chemical Engineering & Technology
(2013)
36
(doi: 10.1002/ceat.201200581)
Synthesis of spongistatin 2 employing a new route to the EF fragment
H Kraus, A Français, M O'Brien, J Frost, A Diéguez-Vázquez, A Polara, N Baricordi, R Horan, D-S Hsu, T Tsunoda, SV Ley
Chemical Science
(2013)
4
(doi: 10.1039/c3sc50304f)
The integration of flow reactors into synthetic organic chemistry
IR Baxendale
Journal of Chemical Technology and Biotechnology
(2013)
88
(doi: 10.1002/jctb.4012)
Synthesis of (-)-hennoxazole A: Integrating batch and flow chemistry methods
A Fernández, ZG Levine, M Baumann, S Sulzer-Mossé, C Sparr, S Schläger, A Metzger, IR Baxendale, SV Ley
Synlett
(2013)
24
(doi: 10.1055/s-0032-1318109)
A Continuous Flow Solution to Achieving Efficient Aerobic Anti-Markovnikov Wacker Oxidation
SL Bourne, SV Ley
Advanced Synthesis and Catalysis
(2013)
342
Flow chemistry synthesis of zolpidem, alpidem and other GABAA agonists and their biological evaluation through the use of in-line frontal affinity chromatography
L Guetzoyan, N Nikbin, IR Baxendale, SV Ley
Chem. Sci.
(2013)
4
(doi: 10.1039/c2sc21850j)
A prototype device for evaporation in batch and flow chemical processes
BJ Deadman, C Battilocchio, E Sliwinski, SV Ley
Green Chemistry
(2013)
15
(doi: 10.1039/c3gc40967h)
Flow Chemistry Syntheses of Styrenes, Unsymmetrical Stilbenes and Branched Aldehydes
SL Bourne, M O'Brien, S Kasinathan, P Koos, P Tolstoy, DX Hu, RW Bates, B Martin, B Schenkel, SV Ley
ChemCatChem
(2012)
5
(doi: 10.1002/cctc.201200778)
The synthesis of Bcr-Abl inhibiting anticancer pharmaceutical agents imatinib, nilotinib and dasatinib.
BJ Deadman, MD Hopkin, IR Baxendale, SV Ley
Organic & Biomolecular Chemistry
(2012)
11
(doi: 10.1039/c2ob27003j)
An expeditious synthesis of imatinib and analogues utilising flow chemistry methods.
MD Hopkin, IR Baxendale, SV Ley
Organic & Biomolecular Chemistry
(2012)
11
(doi: 10.1039/c2ob27002a)
Synthesis and use of a trifluoromethylated azomethine ylide precursor
G Tran, R Meier, L Harris, DL Browne, SV Ley
Journal of Organic Chemistry
(2012)
77
(doi: 10.1021/jo302052m)
Flow microwave technology and microreactors in synthesis
IR Baxendale, C Hornung, SV Ley, J de Mata Muñoz Molina, A Wikström
Australian Journal of Chemistry
(2012)
66
(doi: 10.1071/ch12365)
Yusuf Hamied Department of Chemistry
Lensfield Road
Cambridge
CB2 1EW
T: +44 (0) 1223 336300
enquiries@ch.cam.ac.uk
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