Yusuf Hamied Department of Chemistry

Publications by Professor Steve Ley CBE FRS FMedSci

Efficient batch and continuous flow Suzuki cross-coupling reactions under mild conditions, catalysed by polyurea-encapsulated palladium (II) acetate and tetra-n-butylammonium salts
CKY Lee, AB Holmes, SV Ley, IF McConvey, B Al-Duri, GA Leeke, RCD Santos, JPK Seville
Chemical Communications
(2005)
(doi: 10.1039/b418669a)
Stereoselective synthesis of (2S,7S)-7-(4-phenoxymethyl)2-(1-N-hydroxyureidyl-3-butyn-4-yl)oxepane: a potential anti-asthmatic drug candidate
MK Gurjar, BV Rao, LM Krishna, MS Chorghade, SV Ley
Tetrahedron: Asymmetry
(2005)
16
(doi: 10.1016/j.tetasy.2005.01.024)
A homo-proline tetrazole as an improved organocatalyst for the asymmetric Michael addition of carbonyl compounds to nitro-olefins
SV Ley, CE Mitchell, AJ Cobb
Synlett
(2005)
(doi: 10.1055/s-2005-862392)
Highly diastereoselective desymmetrisation of cyclic meso-anhydrides and derivatisation to mono-protected 1,4-diols
SV Ley, AC Evans, DA Longbottom, M Matsuoka
Synlett
(2005)
(doi: 10.1055/s-2005-862393)
A highly automated, polymer-assisted strategy for the preparation of 2-alkylthiobenzimidazoles and N,N′-dialkylbenzimidazolin-2-ones
E Vickerstaffe, BH Warrington, M Ladlow, SV Ley
Journal of Combinatorial Chemistry
(2005)
7
(doi: 10.1021/cc049832+)
Synthesis of a Ceramide Sphingolipid as a Potential Sex Pheromone of the Hair CrabErimacrus isenbeckiiUsing Butane-2,3-diacetal Desymmetrised Glycolic Acid Building Blocks
SV Ley, DJ Dixon, S Lohmann, TD Sheppard
Synlett
(2005)
(doi: 10.1055/s-2005-862361)
The total synthesis of the annonaceous acetogenin 10-hydroxyasimicin
GL Nattrass, E Díez, MM McLachlan, DJ Dixon, SV Ley
Angewandte Chemie (International ed. in English)
(2005)
44
(doi: 10.1002/anie.200462264)
Supported Reagents and Scavengers in Multi-step Organic Synthesis
IR Baxendale, SV Ley
(2005)
Total synthesis of the Fusarium toxin equisetin
LT Burke, DJ Dixon, SV Ley, F Rodríguez
Organic and Biomolecular Chemistry
(2004)
3
(doi: 10.1039/b411350k)
Organocatalysis with proline derivatives: improved catalysts for the asymmetric Mannich, nitro-Michael and aldol reactions
AJA Cobb, DM Shaw, DA Longbottom, JB Gold, SV Ley
Org Biomol Chem
(2004)
3
(doi: 10.1039/b414742a)
Preparation of enantiopure butane-2,3-diacetals of glycolic acid and alkylation reactions leading to alpha-hydroxyacid and amide derivatives
SV Ley, E Diez, DJ Dixon, RT Guy, P Michel, GL Nattrass, TD Sheppard
Org. Biomol. Chem.
(2004)
2
(doi: 10.1039/b412788a)
Studies on the generation of enolate anions from butane-2,3-diacetal protected glycolic acid derivatives and subsequent highly diastereoselective coupling reactions with aldehydes and acid chlorides.
SV Ley, DJ Dixon, RT Guy, MA Palomero, A Polara, F Rodriguez, TD Sheppard
Org Biomol Chem
(2004)
2
(doi: 10.1029/b412790k)
The first Lewis acid-catalyzed allylboronate additions to aldehydes
DEA Brittain, SV Ley
Chemtracts
(2004)
17
Enantioselective organocatalytic cyclopropanation via ammonium ylides
CD Papageorgiou, MA Cubillo de Dios, SV Ley, MJ Gaunt
Angew Chem Int Ed Engl
(2004)
43
(doi: 10.1002/anie.200460234)
The preparation and alkylation of a butanedione-derived chiral glycine equivalent and its use for the synthesis of α-amino acids and α,α-disubstituted amino acids
CI Harding, DJ Dixon, SV Ley
Tetrahedron
(2004)
60
(doi: 10.1016/j.tet.2004.06.063)
Synthesis of the C-1/C-15 spiroketal fragment (AB) of spongistatin 1.
P Orsini, SV Ley, AS Jessiman, MJ Gaunt
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY
(2004)
228
A concise total synthesis of (+)-okaramine C
PR Hewitt, E Cleator, SV Ley
Organic & Biomolecular Chemistry
(2004)
2
(doi: 10.1039/b410180d)
5-Pyrrolidin-2-yltetrazole as an asymmetric organocatalyst for the addition of ketones to nitro-olefins.
AJA Cobb, DA Longbottom, DM Shaw, SV Ley
Chemical communications (Cambridge, England)
(2004)
10
(doi: 10.1039/b409646k)
Synthesis of the thapsigargins
SV Ley, A Antonello, EP Balskus, DT Booth, SB Christensen, E Cleator, H Gold, K Högenauer, U Hünger, RM Myers, SF Oliver, O Simic, MD Smith, H Søhoel, AJA Woolford
Proceedings of the National Academy of Sciences
(2004)
101
(doi: 10.1073/pnas.0403300101)
Multi-step application of immobilized reagents and scavengers: a total synthesis of epothilone C.
RI Storer, T Takemoto, PS Jackson, DS Brown, IR Baxendale, SV Ley
Chemistry
(2004)
10
(doi: 10.1002/chem.200305669)
Yusuf Hamied Department of Chemistry
Lensfield Road
Cambridge
CB2 1EW
T: +44 (0) 1223 336300
enquiries@ch.cam.ac.uk
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