Yusuf Hamied Department of Chemistry

Publications by Professor Steve Ley CBE FRS FMedSci

Diastereoselective aldol reactions with butane-2,3-diacetal protected glyceraldehyde derivatives.
KR Knudsen, AF Stepan, P Michel, SV Ley
Organic & Biomolecular Chemistry
(2006)
4
(doi: 10.1039/b601888b)
Double Conjugate Addition of Dithiols to Propargylic Carbonyl Systems To Generate Protected 1,3-Dicarbonyl Compounds
HF Sneddon, A van den Heuvel, AKH Hirsch, RA Booth, DM Shaw, MJ Gaunt, SV Ley
Journal of Organic Chemistry
(2006)
71
(doi: 10.1021/jo052514s)
Preparation of the neolignan natural product grossamide by a continuous-flow process
S Ley, I Baxendale, C Griffiths-Jones, G Tranmer
Synlett
(2006)
2006
(doi: 10.1055/s-2006-926244)
A New Strategy for Oligosaccharide Assembly Exploiting Cyclohexane‐1,2‐diacetal Methodology: An Efficient Synthesis of a High Mannose Type Nonasaccharide
P Grice, SV Ley, J Pietruszka, HMI Osborn, HWM Priepke, SL Warriner
Chemistry - A European Journal
(2006)
3
(doi: 10.1002/chem.19970030315)
Sexual development of malaria parasites is inhibited in vitro by the Neem extract Azadirachtin, and its semi-synthetic analogues
IW Jones, AA Denholm, SV Ley, H Lovell, A Wood, RE Sinden
FEMS Microbiology Letters
(2006)
120
(doi: 10.1111/j.1574-6968.1994.tb07044.x)
Diastereoselective aldol reactions with butane-2,3-diacetal protected glyceraldehyde derivatives (vol 4, pg 1471, 2006)
KR Knudsen, AF Stepan, P Michel, SV Ley
ORG BIOMOL CHEM
(2006)
4
Asymmetric organocatalytic conjugate addition of malonates to enones using a proline tetrazole catalyst.
KR Knudsen, CET Mitchell, SV Ley
Chemical communications (Cambridge, England)
(2005)
(doi: 10.1039/b514636d)
Defects in signal transduction caused by a T cell receptor β chain substitution
TA Reno, S Ley, E Sugiyama, A Cantagrel, R Blumberg, J Bonventre, C Terhorst, ET Yeh
European journal of immunology
(2005)
20
(doi: 10.1002/eji.1830200702)
Michael, Michael-aldol and Michael-Michael reactions of enolate equivalents of butane-2,3-diacetal protected glycolic acid derivatives.
SV Ley, DJ Dixon, RT Guy, F Rodríguez, TD Sheppard
Organic & Biomolecular Chemistry
(2005)
3
(doi: 10.1039/b512410g)
Evolution or Revolution: The Challenge to the Modern Medicinal Chemist
IR Baxendale, SV Ley
(2005)
Total synthesis of two novel subpicomolar sarco/endoplasmatic reticulum Ca2+-ATPase inhibitors designed by an analysis of the binding site of thapsigargin.
H Søhoel, T Liljefors, SV Ley, SF Oliver, A Antonello, MD Smith, CE Olsen, JT Isaacs, SB Christensen
J Med Chem
(2005)
48
(doi: 10.1021/jm058036v)
Synthesis of Alkaloid Natural Products Using Solid-Supported Reagents and Scavengers
I Baxendale, S Ley
Current Organic Chemistry
(2005)
9
(doi: 10.2174/138527205774370513)
A versatile organocatalyst for the asymmetric conjugate addition of nitroalkanes to enones
CET Mitchell, SE Brenner, SV Ley
Chemical Communications
(2005)
(doi: 10.1039/b511441a)
Foreword
P Nolan
(2005)
(doi: 10.1002/3527606858)
A highly selective, organocatalytic route to chiral dihydro-1,2-oxazines.
S Kumarn, DM Shaw, DA Longbottom, SV Ley
Organic letters
(2005)
7
(doi: 10.1021/ol051577u)
Total Synthesis of Spongistatin 1: A Synthetic Strategy Exploiting Its Latent Pseudo‐Symmetry
M Ball, MJ Gaunt, DF Hook, AS Jessiman, S Kawahara, P Orsini, A Scolaro, AC Talbot, HR Tanner, S Yamanoi, SV Ley
Angewandte Chemie International Edition
(2005)
44
(doi: 10.1002/anie.200502008)
Synthesis of the EF fragment of spongistatin 1
SV Ley, S Kawahara, MJ Gaunt, A Scolaro, S Yamanoi
Synlett
(2005)
(doi: 10.1055/s-2005-871960)
Non-metal-catalysed intramolecular alkyne cyclotrimerization reactions promoted by focussed microwave heating in batch and flow modes
S Saaby, IR Baxendale, SV Ley
Organic & Biomolecular Chemistry
(2005)
3
(doi: 10.1039/b509540a)
A phase-switch purification approach for the expedient removal of tagged reagents and scavengers following their application in organic synthesis.
J Siu, IR Baxendale, RA Lewthwaite, SV Ley
Organic & biomolecular chemistry
(2005)
3
(doi: 10.1039/b503778f)
Azadirachtin disrupts formation of organised microtubule arrays during microgametogenesis of Plasmodium berghei.
O Billker, MK Shaw, IW Jones, SV Ley, AJ Mordue, RE Sinden
J Eukaryot Microbiol
(2005)
49
(doi: 10.1111/j.1550-7408.2002.tb00234.x)
Yusuf Hamied Department of Chemistry
Lensfield Road
Cambridge
CB2 1EW
T: +44 (0) 1223 336300
enquiries@ch.cam.ac.uk
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