Publications by Professor Steve Ley CBE FRS FMedSci

Fully automated continuous flow synthesis of 4,5-disubstituted oxazoles

M Baumann, IR Baxendale, SV Ley, CD Smith, GK Tranmer

Organic Letters

(2006)

5231

(doi: 10.1021/ol061975c)

Stereocontrolled total synthesis of bengazole a: a marine bisoxazole natural product displaying potent antifungal properties.

JA Bull, EP Balskus, RAJ Horan, M Langner, SV Ley

Angew Chem Int Ed Engl

(2006)

6714

(doi: 10.1002/anie.200602050)

An enantioselective organocatalytic route to chiral 3,6-dihydropyridazines from aldehydes

S Ley, A Oelke, S Kumarn, D Longbottom

Synlett

(2006)

2006

2548

(doi: 10.1055/s-2006-951486)

ORGN 141-Asymmetric organocatalytic conjugate addition of malonates to enones using a proline tetrazole catalyst

KR Knudsen, CET Mitchell, S Brenner, SV Ley

ABSTR PAP AM CHEM S

(2006)

232

Enantioselective catalytic intramolecular cyclopropanation using modified cinchona alkaloid organocatalysts.

CCC Johansson, N Bremeyer, SV Ley, DR Owen, SC Smith, MJ Gaunt

Angewandte Chemie International Edition

(2006)

6024

(doi: 10.1002/anie.200602129)

8,9,10,10a-Tetrahydro-6H-tetrazolo[1,5-a]pyrrolo[2,1-c]pyrazines: New Heterocyclic Frameworks Generated by an Ugi-Type Multicomponent Reaction

S Ley, V Franckevičius, D Longbottom, R Turner

Synthesis

(2006)

2006

3215

(doi: 10.1055/s-2006-950219)

Hydrogenation of aromatic ketones, aldehydes, and epoxides with hydrogen and Pd(0)EnCat™ 30NP

SV Ley, AJP Stewart-Liddon, D Pears, RH Perni, K Treacher

Beilstein J Org Chem

(2006)

(doi: 10.1186/1860-5397-2-15)

A highly selective, organocatalytic route to chiral 1,2-oxazines from ketones.

S Kumarn, DM Shaw, SV Ley

Chemical Communications

(2006)

3211

(doi: 10.1039/b606338a)

Natural Products as an Inspiration for the Discovery of New High-Throughput Chemical Synthesis Tools

SV Ley, IR Baxendale, DA Longbottom, RM Myers

(2006)

(doi: 10.1002/9780470085226.ch2)

Microwave-assisted Suzuki coupling reactions with an encapsulated palladium catalyst for batch and continuous-flow transformations

IR Baxendale, CM Griffiths-Jones, SV Ley, GK Tranmer

Chemistry (Weinheim an der Bergstrasse, Germany)

(2006)

4407

(doi: 10.1002/chem.200501400)

The Use of Polymer Supported Reagents and Scavengers in the Synthesis of Natural Products

SV Ley, IR Baxendale, RM Myers

(2006)

131

(doi: 10.1201/9781420009279)

Effect of azadirachtin‐derived decalin (perhydronaphthalene) and dihydrofuranacetal (furo[2, 3‐fo]pyran) fragments on the feeding behaviour of Spodoptera littoralis

WM Blaney, MSJ Simmonds, SV Ley, JC Anderson, SC Smith, A Wood

Pest Management Science

(2006)

169

(doi: 10.1002/ps.2780400212)

Microwave flow chemistry: the next evolutionary step in synthetic chemistry?

IR Baxendale, MR Pitts

Chimica Oggi

(2006)

Progress towards avermectins and milbemycins

SV Ley

Pest Management Science

(2006)

153

(doi: 10.1002/ps.2780180210)

Targeting C-reactive protein for the treatment of cardiovascular disease

MB Pepys, GM Hirschfield, GA Tennent, JR Gallimore, MC Kahan, V Bellotti, PN Hawkins, RM Myers, MD Smith, A Polara, AJA Cobb, SV Ley, JA Aquilina, CV Robinson, I Sharif, GA Gray, CA Sabin, MC Jenvey, SE Kolstoe, D Thompson, SP Wood

Nature

(2006)

440

1217

(doi: 10.1038/nature04672)

Chemical variation of natural product-like scaffolds: design and synthesis of spiroketal derivatives.

G Zinzalla, L-G Milroy, SV Ley

Organic & biomolecular chemistry

(2006)

1977

(doi: 10.1039/b603015g)