Yusuf Hamied Department of Chemistry

Publications by Professor Steve Ley CBE FRS FMedSci

Flow chemistry for natural product synthesis: Towards the syntheses of spiragiens A and B
CF Carter, H Lange, S Newton, SV Ley
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY
(2010)
240
‘The changing face of organic synthesis’
SV Ley
Tetrahedron
(2010)
66
(doi: 10.1016/j.tet.2010.05.049)
Total synthesis of chloptosin.
AJ Oelke, DJ France, T Hofmann, G Wuitschik, SV Ley
Angew Chem Int Ed Engl
(2010)
49
(doi: 10.1002/anie.201002880)
KMnO4-Mediated Oxidation as a Continuous Flow Process
J Sedelmeier, SV Ley, IR Baxendale, M Baumann
Organic Letters
(2010)
12
(doi: 10.1021/ol101345z)
A palladium wall coated microcapillary reactor for use in continuous flow transfer hydrogenation
CH Hornung, B Hallmark, MR Mackley, IR Baxendale, SV Ley
Advanced Synthesis and Catalysis
(2010)
352
(doi: 10.1002/adsc.201000139)
Enzymatic Oxidative Cyclisation Reactions Leading to Dibenzoazocanes
F Tozzi, S Ley, M Kitching, I Baxendale
Synlett
(2010)
2010
(doi: 10.1055/s-0030-1258486)
The application of flow microreactors to the preparation of a family of casein kinase I inhibitors.
F Venturoni, N Nikbin, SV Ley, IR Baxendale
Organic & Biomolecular Chemistry
(2010)
8
(doi: 10.1039/b925327k)
Multiple microcapillary reactor for organic synthesis
CH Hornung, B Hallmark, M Baumann, IR Baxendale, SV Ley, P Hester, P Clayton, MR Mackley
Industrial & Engineering Chemistry Research
(2010)
49
(doi: 10.1021/ie901674h)
Novel palindromic ligands cementing the native quaternary structure of transthyretin
PP Mangione, V Bellotti, S Deroo, GW Taylor, MG McCammon, CV Robinson, GA Tennent, MD Smith, AJ Morrison, AJA Cobb, A Coyne, SV Ley, SW Wood, MB Pepys
AMYLOID-JOURNAL OF PROTEIN FOLDING DISORDERS
(2010)
17
Targeting transthyretin - X-ray crystallography and rational drug design
S Kolstoe, AJ Morrison, AJA Cobb, A Coyne, R Gill, MD Smith, SV Ley, SP Wood, MB Pepys
AMYLOID-JOURNAL OF PROTEIN FOLDING DISORDERS
(2010)
17
Green Chemistry in the Pharmaceutical Industry
G Whittington
(2010)
(doi: 10.1002/9783527629688)
Flow ozonolysis using a semipermeable Teflon AF-2400 membrane to effect gas - Liquid contact
M O'Brien, IR Baxendale, SV Ley
Organic letters
(2010)
12
(doi: 10.1021/ol100322t)
A flow-based synthesis of Imatinib: the API of Gleevec
MD Hopkin, IR Baxendale, SV Ley
Chem Commun (Camb)
(2010)
46
(doi: 10.1039/c001550d)
SYNTHESIS OF HIGHLY SUBSTITUTED NITROPYRROLIDINES, NITROPYRROLIZINES AND NITROPYRROLES VIA MULTICOMPONENT-MULTISTEP SEQUENCES WITHIN A FLOW REACTOR
S V. Ley, M Baumann, I R. Baxendale, A Kirschning, J Wegner
Heterocycles
(2010)
82
(doi: 10.3987/com-10-s(e)77)
The continuous flow synthesis of butane-2,3-diacetal protected building blocks using microreactors.
CF Carter, IR Baxendale, JBJ Pavey, SV Ley
Organic and Biomolecular Chemistry
(2010)
8
(doi: 10.1039/b924309g)
A Flow Process Using Microreactors for the Preparation of a Quinolone Derivative as a Potent 5HT1B Antagonist
S Ley, Z Qian, I Baxendale
Synlett
(2010)
2010
(doi: 10.1055/s-0029-1219358)
ReactIR Flow Cell: A New Analytical Tool for Continuous Flow Chemical Processing
CF Carter, H Lange, SV Ley, IR Baxendale, B Wittkamp, JG Goode, NL Gaunt
Organic Process Research and Development
(2010)
14
(doi: 10.1021/op900305v)
Synthesis of 3-Nitropyrrolidines via Dipolar Cycloaddition Reactions Using a Modular Flow Reactor
S Ley, M Baumann, I Baxendale
Synlett
(2010)
2010
(doi: 10.1055/s-0029-1219344)
Multi-Step Synthesis by Using Modular Flow Reactors: The Preparation of Yne-Ones and Their Use in Heterocycle Synthesis
IR Baxendale, SC Schou, J Sedelmeier, SV Ley
Chemistry - A European Journal
(2009)
16
(doi: 10.1002/chem.200902906)
An asymmetric tandem conjugative addition-intramolecular cyclisation process to provide functionalised 3,6-dihydropyrans and 4,5- epoxytetrahydropyrans
S Catalán‐Muñoz, CA Müller, SV Ley
European Journal of Organic Chemistry
(2009)
2010
(doi: 10.1002/ejoc.200901145)
Yusuf Hamied Department of Chemistry
Lensfield Road
Cambridge
CB2 1EW
T: +44 (0) 1223 336300
enquiries@ch.cam.ac.uk
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