Yusuf Hamied Department of Chemistry

Publications by Professor Steve Ley CBE FRS FMedSci

Synthesis of a Drug-Like Focused Library of Trisubstituted Pyrrolidines Using Integrated Flow Chemistry and Batch Methods
M Baumann, IR Baxendale, C Kuratli, SV Ley, RE Martin, J Schneider
ACS Comb Sci
(2011)
13
(doi: 10.1021/co2000357)
Retinoic acid receptor signaling regulates choroid fissure closure through independent mechanisms in the ventral optic cup and periocular mesenchyme.
G Lupo, G Gestri, M O'Brien, RM Denton, RAS Chandraratna, SV Ley, WA Harris, SW Wilson
Proc Natl Acad Sci U S A
(2011)
108
(doi: 10.1073/pnas.1103802108)
A breakthrough method for the accurate addition of reagents in multi-step segmented flow processing
H Lange, CF Carter, MD Hopkin, A Burke, JG Goode, IR Baxendale, SV Ley
Chemical Science
(2011)
2
(doi: 10.1039/c0sc00603c)
An overview of the key routes to the best selling 5-membered ring heterocyclic pharmaceuticals.
M Baumann, IR Baxendale, SV Ley, N Nikbin
Beilstein Journal of Organic Chemistry
(2011)
7
(doi: 10.3762/bjoc.7.57)
Azadirachtin: structural requirements for reducing growth and increasing mortality in lepidopterous larvae
MSJ Simmonds, WM Blaney, SV Ley, JC Anderson, PL Toogood
Entomologia Experimentalis et Applicata
(2011)
55
(doi: 10.1111/j.1570-7458.1990.tb01360.x)
Insect antifeedants: a behavioural and electrophysiological investigation of natural and synthetically derived clerodane diterpenoids
WM Blaney, MSJ Simmonds, SV Ley, PS Jones
Entomologia Experimentalis Et Applicata
(2011)
46
(doi: 10.1111/j.1570-7458.1988.tb01121.x)
Lesser-known enabling technologies for organic synthesis
M O'Brien, R Denton, SV Ley
Synthesis
(2011)
(doi: 10.1055/s-0030-1259979)
In-line monitoring for the accurate control of segmented flow processes
CF Carter, SV Ley
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY
(2011)
241
Oxidation reactions in segmented and continuous flow chemical processing using an N -(tert -Butyl)phenylsulfinimidoyl chloride monolith
H Lange, MJ Capener, AX Jones, CJ Smith, N Nikbin, IR Baxendale, SV Ley
Synlett
(2011)
(doi: 10.1055/s-0030-1259923)
Total synthesis of chloptosin: a dimeric cyclohexapeptide.
AJ Oelke, F Antonietti, L Bertone, PB Cranwell, DJ France, RJM Goss, T Hofmann, S Knauer, SJ Moss, PC Skelton, RM Turner, G Wuitschik, SV Ley
Chemistry – A European Journal
(2011)
17
(doi: 10.1002/chem.201003216)
Continuous flow processing of slurries: Evaluation of an agitated cell reactor
DL Browne, BJ Deadman, R Ashe, IR Baxendale, SV Ley
Organic Process Research & Development
(2011)
15
(doi: 10.1021/op2000223)
Diastereoselective Chain-Elongation Reactions Using Microreactors for Applications in Complex Molecule Assembly
CF Carter, H Lange, D Sakai, IR Baxendale, SV Ley
Chemistry – A European Journal
(2011)
17
(doi: 10.1002/chem.201003148)
Allosteric Modulation of Hormone Release from Thyroxine and Corticosteroid-binding Globulins
X Qi, F Loiseau, WL Chan, Y Yan, Z Wei, L-G Milroy, RM Myers, SV Ley, RJ Read, RW Carrell, A Zhou
J Biol Chem
(2011)
286
(doi: 10.1074/jbc.m110.171082)
The continuous-flow synthesis of carboxylic acids using CO2 in a tube-in-tube gas permeable membrane reactor.
A Polyzos, M O'Brien, TP Petersen, IR Baxendale, SV Ley
Angew Chem Int Ed Engl
(2011)
50
(doi: 10.1002/anie.201006618)
A fully automated, multistep flow synthesis of 5-amino-4-cyano-1,2,3-triazoles.
CJ Smith, N Nikbin, SV Ley, H Lange, IR Baxendale
Organic & biomolecular chemistry
(2011)
9
(doi: 10.1039/c0ob00815j)
Flow synthesis of organic azides and the multistep synthesis of imines and amines using a new monolithic triphenylphosphine reagent
CJ Smith, CD Smith, N Nikbin, SV Ley, IR Baxendale
Organic & Biomolecular Chemistry
(2011)
9
(doi: 10.1039/c0ob00813c)
An integrated flow and batch-based approach for the synthesis of O -methyl siphonazole
M Baumann, IR Baxendale, M Brasholz, JJ Hayward, SV Ley, N Nikbin
Synlett
(2011)
(doi: 10.1055/s-0030-1260573)
New Synthetic Technologies in Medicinal Chemistry Foreword
SV Ley
(2011)
11
(doi: 10.1039/9781849733052-FP005)
10.1007/BF00364198
CrossRef Listing of Deleted DOIs
(2011)
(doi: 10.1007/bf00364198)
Topics in Current Chemistry: Foreword
SV Ley
(2011)
301
(doi: 10.1007/978-3-642-20914-7)
Yusuf Hamied Department of Chemistry
Lensfield Road
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CB2 1EW
T: +44 (0) 1223 336300
enquiries@ch.cam.ac.uk
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