Yusuf Hamied Department of Chemistry

Publications by Professor Steve Ley CBE FRS FMedSci

The Lab of the Future. the importance of remote monitoring and control
MD Hopkin, IR Baxendale, SV Ley
Chimica Oggi Chemistry Today
(2012)
30
Increased endothelial cell selectivity of triazole-bridged dihalogenated A-ring analogues of combretastatin A-1
TM Beale, PJ Bond, JD Brenton, DS Charnock-Jones, SV Ley, RM Myers
Bioorganic and Medicinal Chemistry
(2012)
20
(doi: 10.1016/j.bmc.2012.01.010)
The molecular basis for selective inhibition of unconventional mRNA splicing by an IRE1-binding small molecule
BCS Cross, PJ Bond, PG Sadowski, BK Jha, J Zak, JM Goodman, RH Silverman, TA Neubert, IR Baxendale, D Ron, HP Harding
Proc Natl Acad Sci U S A
(2012)
109
(doi: 10.1073/pnas.1115623109)
Scale-up of flow-assisted synthesis of C 2-symmetric chiral PyBox ligands
C Battilocchio, M Baumann, IR Baxendale, M Biava, MO Kitching, SV Ley, RE Martin, SA Ohnmacht, NDC Tappin
Synthesis
(2012)
44
(doi: 10.1055/s-0031-1289676)
A-Ring Dihalogenation Increases the Cellular Activity of Combretastatin-Templated Tetrazoles
TM Beale, DM Allwood, A Bender, PJ Bond, JD Brenton, DS Charnock-Jones, SV Ley, RM Myers, JW Shearman, J Temple, J Unger, CA Watts, J Xian
ACS Medicinal Chemistry Letters
(2012)
3
(doi: 10.1021/ml200149g)
A total synthesis of millingtonine a
J Wegner, SV Ley, A Kirschning, A-L Hansen, JM Garcia, IR Baxendale
Org Lett
(2012)
14
(doi: 10.1021/ol203158p)
Twenty five years of azadirachtins
HE Hummel, DF Hein, W Kraus, SV Ley, ED Morgan, H Schmutterer
MITTEILUNGEN DER DEUTSCHEN GESELLSCHAFT FUR ALLGEMEINE UND ANGEWANDTE ENTOMOLOGIE, BD 18
(2012)
18
Discovery, design and synthesis of a novel series of non-peptidomimetic inhibitors of XIAP-caspase 9 interactions
DM Allwood, RM Myers, F Richards, A Bender, C Watts, SV Ley
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY
(2012)
243
Continuous stream processing: A prototype magnetic field induced flow mixer
P Koos, DL Browne, SV Ley
gps
(2012)
1
(doi: 10.1515/greenps-2011-0501)
Piecing together the puzzle: understanding a mild, metal free reduction method for the large scale synthesis of hydrazines
DL Browne, IR Baxendale, SV Ley
Tetrahedron
(2011)
67
(doi: 10.1016/j.tet.2011.09.146)
The application of a monolithic triphenylphosphine reagent for conducting Appel reactions in flow microreactors
KA Roper, H Lange, A Polyzos, MB Berry, IR Baxendale, SV Ley
Beilstein Journal of Organic Chemistry
(2011)
7
(doi: 10.3762/bjoc.7.194)
Continuous Preparation of Arylmagnesium Reagents in Flow with Inline IR Monitoring
T Brodmann, P Koos, A Metzger, P Knochel, SV Ley
Organic Process Research & Development
(2011)
16
(doi: 10.1021/op200275d)
Syngas-Mediated C-C Bond Formation in Flow: Selective Rhodium-Catalysed Hydroformylation of Styrenes
S Ley, S Kasinathan, S Bourne, P Tolstoy, P Koos, M O’Brien, R Bates, I Baxendale
Synlett
(2011)
2011
(doi: 10.1055/s-0031-1289292)
The Continuous-Flow Synthesis of Styrenes Using Ethylene in a Palladium-Catalysed Heck Cross-Coupling Reaction
S Ley, S Bourne, P Koos, M O’Brien, B Martin, B Schenkel, I Baxendale
Synlett
(2011)
2011
(doi: 10.1055/s-0031-1289291)
The oxygen-mediated synthesis of 1,3-butadiynes in continuous flow: Using teflon AF-2400 to effect gas/liquid contact
TP Petersen, A Polyzos, M O'Brien, T Ulven, IR Baxendale, SV Ley
ChemSusChem
(2011)
5
(doi: 10.1002/cssc.201100339)
Teflon AF-2400 mediated gas-liquid contact in continuous flow methoxycarbonylations and in-line FTIR measurement of CO concentration.
P Koos, U Gross, A Polyzos, M O'Brien, I Baxendale, SV Ley
Organic & biomolecular chemistry
(2011)
9
(doi: 10.1039/c1ob06017a)
The flow synthesis of heterocycles for natural product and medicinal chemistry applications
M Baumann, IR Baxendale, SV Ley
Molecular Diversity
(2011)
15
(doi: 10.1007/s11030-010-9282-1)
Practical Synthetic Organic Chemistry
SV Ley
Practical Synthetic Organic Chemistry Reactions Principles and Techniques
(2011)
(doi: 10.1002/9781118093559)
Piperazic acid-containing natural products: Isolation, biological relevance and total synthesis
AJ Oelke, DJ France, T Hofmann, G Wuitschik, SV Ley
Natural product reports
(2011)
28
(doi: 10.1039/c1np00041a)
Hydrogenation in flow: Homogeneous and heterogeneous catalysis using Teflon AF-2400 to effect gas-liquid contact at elevated pressure
M O'Brien, N Taylor, A Polyzos, IR Baxendale, SV Ley
Chemical Science
(2011)
2
(doi: 10.1039/c1sc00055a)
Yusuf Hamied Department of Chemistry
Lensfield Road
Cambridge
CB2 1EW
T: +44 (0) 1223 336300
enquiries@ch.cam.ac.uk
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