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Yusuf Hamied Department of Chemistry

 

Publications by Professor Ian Paterson FRSE FRS

Large-scale synthesis of the anti-cancer marine natural product (+)-discodermolide. Part 4: Preparation of fragment C7-24
SJ Mickel, GH Sedelmeier, D Niederer, F Schuerch, M Seger, K Schreiner, R Daeffler, A Osmani, D Bixel, O Loiseleur, J Cercus, H Stettler, K Schaer, R Gamboni, A Bach, GP Chen, WC Chen, P Geng, GT Lee, E Loeser, J McKenna, FR Kinder, K Konigsberger, K Prasad, TM Ramsey, N Reel, O Repic, L Rogers, WC Shieh, RM Wang, L Waykole, S Xue, G Florence, I Paterson
– Organic Process Research & Development
(2003)
8,
113
(DOI: 10.1021/op034133r)
Synthesis of novel discodermolide analogues with modified hydrogen-bonding donor/acceptor sites
I Paterson, O Delgado
– Tetrahedron Letters
(2003)
44,
8877
(DOI: 10.1016/j.tetlet.2003.09.172)
Stereocontrolled Total Synthesis of (−)-Callipeltoside A
I Paterson, RDM Davies, AC Heimann, R Marquez, A Meyer
– Organic letters
(2003)
5,
4477
(DOI: 10.1021/ol0357853)
A fully stereocontrolled total synthesis of (+)-leucascandrolide A
I Paterson, M Tudge
– Tetrahedron
(2003)
59,
6833
(DOI: 10.1016/S0040-4020(03)00814-7)
The Development of a Practical Total Synthesis of Discodermolide, a Promising Microtubule‐Stabilizing Anticancer Agent
I Paterson, GJ Florence
– European Journal of Organic Chemistry
(2003)
2003,
2193
(DOI: 10.1002/ejoc.200300061)
Toward the total synthesis of phorboxazole A: synthesis of an advanced C4–C32 subunit using the Jacobsen hetero Diels–Alder reaction
I Paterson, CA Luckhurst
– Tetrahedron Letters
(2003)
44,
3749
(DOI: 10.1016/s0040-4039(03)00754-8)
Toward the synthesis of reidispongiolide a: stereocontrolled synthesis of the C17-C22 and C23-C35 degradation fragments.
I Paterson, K Ashton, R Britton, H Knust
– Org Lett
(2003)
5,
1963
(DOI: 10.1021/ol034558y)
Discodermolide interferes with the binding of tau protein to microtubules
S Kar, GJ Florence, I Paterson, LA Amos
– FEBS Letters
(2003)
539,
34
(DOI: 10.1016/s0014-5793(03)00181-9)
A highly enantioselective catalyst for the asymmetric Nozaki-Hiyama-Kishi reaction of allylic and vinylic halides
A Berkessel, D Menche, CA Sklorz, M Schröder, I Paterson
– Angewandte Chemie (International ed. in English)
(2003)
42,
1032
(DOI: 10.1002/anie.200390265)
Studies toward the total synthesis of the callipeltosides.
A Meyer, RDM Davies, A Heimann, R Marquez, I Paterson
– ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY
(2003)
225,
U417
Toward the synthesis of peloruside a: fragment synthesis and coupling studies.
I Paterson, ME Di Francesco, T Kühn
– Organic Letters
(2003)
5,
599
(DOI: 10.1021/ol034035q)
Synthesis and biological evaluation of spongistatin/altohyrtin analogues: E-ring dehydration and C46 side-chain truncationElectronic supplementary information (ESI) available: spectroscopic data for compounds 2 and 3. See http://www.rsc.org/suppdata/cc/b2/b212651f/
I Paterson, JL Aceña, J Bach, DYK Chen, MJ Coster
– Chemical communications (Cambridge, England)
(2003)
462
(DOI: 10.1039/b212651f)
Stereocontrolled Total Synthesis of (+)‐Leucascandrolide A
I Paterson, M Tudge
– Angew Chem Int Ed Engl
(2003)
42,
343
(DOI: 10.1002/anie.200390112)
Actin-Binding Marine Macrolides: Total Synthesis and Biological Importance
K-S Yeung, I Paterson
– Angewandte Chemie International Edition
(2002)
41,
4632
(DOI: 10.1002/anie.200290057)
1,6-Asymmetric Induction in Boron-Mediated Aldol Reactions: Application to a Practical Total Synthesis of (+)-Discodermolide
I Paterson, O Delgado, GJ Florence, I Lyothier, JP Scott, N Sereinig
– Organic Letters
(2002)
5,
35
(DOI: 10.1021/ol0270780)
Studies in marine macrolide synthesis: stereocontrolled synthesis of a C21–C34 subunit of the aplyronines
I Paterson, SB Blakey, CJ Cowden
– Tetrahedron Letters
(2002)
43,
6005
(DOI: 10.1016/s0040-4039(02)01217-0)
Synthesis and antitumor activity of analogs of the novel microtubule stabilizing agent discodermolide.
FR Kinder, KW Bair, WC Chen, G Florence, C Francavilla, P Geng, S Gunasekera, PT Lassota, RE Longley, MG Palermo, I Paterson, S Pomponi, TM Ramsey, L Rogers, M Sabio, N Sereinig, E Sorensen, RM Wang, A Wright, Q Guo
– ABSTR PAP AM CHEM S
(2002)
224,
U47
Synthesis of spongistatin 1 (aplyronine A) and structural analogs.
I Paterson
– ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY
(2002)
224,
U48
Toward the Combinatorial Synthesis of Polyketide Libraries:  Asymmetric Aldol Reactions with α-Chiral Aldehydes on Solid Support
I Paterson, T Temal-Laïb
– Organic letters
(2002)
4,
2473
(DOI: 10.1021/ol026046+)
HIGH PI-FACE SELECTIVITY IN ANTI-ALDOL REACTIONS OF E-ENOL BORINATES FROM CHIRAL ALKOXYMETHYL KETONES - STEREOCONTROLLED SYNTHESIS OF A C24-C32 POLYOL SUBUNIT OF RAPAMYCIN
I PATERSON, RD TILLYER
– The Journal of Organic Chemistry
(2002)
58,
4182
(DOI: 10.1021/jo00068a002)

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