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Yusuf Hamied Department of Chemistry

 
The stereocontrolled total synthesis of altohyrtin A/spongistatin 1: The CD-spiroacetal segment
I Paterson, MJ Coster, DY-K Chen, KR Gibson, DJ Wallace
– Organic & Biomolecular Chemistry
(2005)
3,
2410
The stereocontrolled total synthesis of altohyrtin A/spongistatin 1: fragment couplings, completion of the synthesis, analogue generation and biological evaluation
I Paterson, DY-K Chen, MJ Coster, JL Aceña, J Bach, DJ Wallace
– Organic & biomolecular chemistry
(2005)
3,
2431
The stereocontrolled total synthesis of altohyrtin A /spongistatin 1: the southern hemisphere EF segment
I Paterson, MJ Coster, DY-K Chen, JL Aceña, J Bach, LE Keown, T Trieselmann
– Organic & Biomolecular Chemistry
(2005)
3,
2420
Conformational studies and solution structure of laulimalide and simplified analogues using NMR spectroscopy and molecular modelling
I Paterson, D Menche, R Britton, AE Hakansson, MA Silva-Martinez
– Tetrahedron Letters
(2005)
46,
3677
Design, synthesis and biological evaluation of novel, simplified analogues of laulimalide: modification of the side chain
I Paterson, D Menche, AE Håkansson, A Longstaff, D Wong, I Barasoain, RM Buey, JF Díaz
– Bioorganic & medicinal chemistry letters
(2005)
15,
2243
Studies towards a total synthesis of spirastrellolide A.
EA Anderson, SM Dalby, O Loiseleur, I Paterson
– ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY
(2005)
229,
U378
Studies towards the total synthesis of neolaulimalide, laulimalide and biologically active analogues
I Paterson, A Longstaff, D Menche, DJ Wong
– ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY
(2005)
229,
U519
Studies towards the total synthesis of peloruside A
SJ Atkinson, I Paterson, ME Di Francesco, T Kuhn, M Lochner, K Lorenz
– ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY
(2005)
229,
U521
Stereocontrolled Total Synthesis of (−)‐Aurisides A and B
I Paterson, GJ Florence, AC Heimann, AC Mackay
– Angewandte Chemie International Edition
(2005)
44,
1130
A Second-Generation Total Synthesis of (+)-Discodermolide:  The Development of a Practical Route Using Solely Substrate-Based Stereocontrol
I Paterson, O Delgado, GJ Florence, I Lyothier, M O'Brien, JP Scott, N Sereinig
– The Journal of Organic Chemistry
(2004)
70,
150
Total synthesis of (+)-discodermolide: an improved endgame exploiting a Still-Gennari-type olefination with a C1-C8 beta-ketophosphonate fragment.
I Paterson, I Lyothier
– Org Lett
(2004)
6,
4933
Total Synthesis and Configurational Assignment of (−)‐Dictyostatin, a Microtubule‐Stabilizing Macrolide of Marine Sponge Origin
I Paterson, R Britton, O Delgado, A Meyer, KG Poullennec
– Angew Chem Int Ed Engl
(2004)
43,
4629
Studies Towards the Synthesis of Superstolide A: An Aldol-Based Construction of an Advanced C1-C5/C20-C26 Segment
I Paterson, AC Mackay
– Synlett
(2004)
1359
Synthesis of antimicrofilament marine macrolides: Synthesis and configurational assignment of a C5–C16 degradation fragment of reidispongiolide A
I Paterson, R Britton, K Ashton, H Knust, J Stafford
– Proceedings of the National Academy of Sciences
(2004)
101,
11986
A quantitative evaluation of the effects of inhibitors of tubulin assembly on polymerization induced by discodermolide, epothilone B, and paclitaxel.
DA Dabydeen, GJ Florence, I Paterson, E Hamel
– Cancer chemotherapy and pharmacology
(2004)
53,
397
Stereochemical determination of dictyostatin, a novel microtubule-stabilising macrolide from the marine sponge Corallistidae sp.Electronic supplementary information (ESI) available: copies of 1D and 2D NMR spectra, tables of spectral data and calculated torsion angles. See http://www.rsc.org/suppdata/cc/b3/b316390c/
I Paterson, R Britton, O Delgado, AE Wright
– Chemical communications (Cambridge, England)
(2004)
632
Synthesis of Novel 11-Desmethyl Analogues of Laulimalide by Nozaki−Kishi Coupling
I Paterson, H Bergmann, D Menche, A Berkessel
– Organic letters
(2004)
6,
1293
Phorboxazole B synthetic studies: construction of C(1-32) and C(33-46) subtargets
I Paterson, A Steven, CA Luckhurst
– Org Biomol Chem
(2004)
2,
3026
Total synthesis of spongistatin 1 (altohyrtin A): a tale of ten aldols
I Paterson, MJ Coster
(2004)
8
Large-scale synthesis of the anti-cancer marine natural product (+)-discodermolide. Part 4: Preparation of fragment C7-24
SJ Mickel, GH Sedelmeier, D Niederer, F Schuerch, M Seger, K Schreiner, R Daeffler, A Osmani, D Bixel, O Loiseleur, J Cercus, H Stettler, K Schaer, R Gamboni, A Bach, GP Chen, WC Chen, P Geng, GT Lee, E Loeser, J McKenna, FR Kinder, K Konigsberger, K Prasad, TM Ramsey, N Reel, O Repic, L Rogers, WC Shieh, RM Wang, L Waykole, S Xue, G Florence, I Paterson
– Organic Process Research & Development
(2003)
8,
113