Total synthesis of (-)-reidispongiolide A, an actin-targeting marine macrolide.
Angewandte Chemie International Edition
(2007)
46
6167
(doi: 10.1002/anie.200702178)
Total synthesis and stereochemical reassignment of (+)-dolastatin 19, a cytotoxic marine macrolide isolated from Dolabella auricularia
Tetrahedron
(2007)
63
5806
(doi: 10.1016/j.tet.2007.01.048)
Synthesis and biological evaluation of novel analogues of dictyostatin
Bioorganic & Medicinal Chemistry Letters
(2007)
17
2443
(doi: 10.1016/j.bmcl.2007.02.031)
Synthesis of two diastereomeric C1–C22fragments of spirastrellolide A
Chemical Communications
(2007)
1852
(doi: 10.1039/b700827a)
Design, synthesis and biological evaluation of a macrocyclic discodermolide/dictyostatin hybrid
Chemical communications (Cambridge, England)
(2007)
49
(doi: 10.1039/b615122a)
The tubulin-bound conformation of discodermolide derived by NMR studies in solution supports a common pharmacophore model for epothilone and discodermolide.
Angewandte Chemie International Edition
(2006)
45
7388
(doi: 10.1002/anie.200602793)
Synthesis of the DEF-bis-spiroacetal of spirastrellolide A exploiting a double asymmetric dihydroxylation/spiroacetalisation strategy.
Chem Commun (Camb)
(2006)
4186
(doi: 10.1039/b612697a)
Synergistic effects of peloruside A and laulimalide with taxoid site drugs, but not with each other, on tubulin assembly
Molecular pharmacology
(2006)
70
1555
(doi: 10.1124/mol.106.027847)
Preparation of tritium‐labelled meta‐aminolevamisole of high specific radioactivity by catalytic dehalogenation
Journal of Labelled Compounds and Radiopharmaceuticals
(2006)
21
945
(doi: 10.1002/jlcr.2580211009)
Total Synthesis and Stereochemical Reassignment of (+)-Dolastatin 19
Organic letters
(2006)
8
2131
(doi: 10.1021/ol060609q)
Synthesis of novel 11-desmethyl analogues of laulimalide by Nozaki-Kishi coupling (vol 15, pg 2243, 2005)
Organic Letters
(2006)
8
1511
(doi: 10.1021/ol060252q)
Synthesis of the C1-C21 southern hemisphere of the originally proposed structure of spirastrellolide a
Synthesis
(2005)
3225
(doi: 10.1055/S-2005-918449)
Microtubule interactions with chemically diverse stabilizing agents: Thermodynamics of binding to the paclitaxel site predicts cytotoxicity
Chem Biol
(2005)
12
1269
The Renaissance of Natural Products as Drug Candidates
Science
(2005)
310
451
(doi: 10.1126/science.1116364)
Advances in the Total Synthesis of Biologically Important Marine Macrolides †
Chem Rev
(2005)
105
4237
(doi: 10.1021/cr040614c)
Toward the Synthesis of Spirastrellolide A: Construction of Two C1−C25 Diastereomers Containing the BC−Spiroacetal
Organic Letters
(2005)
7
4125
(doi: 10.1021/ol051405x)
Toward the Synthesis of Spirastrellolide A: Construction of a Tetracyclic C26−C40 Subunit Containing the DEF-Bis-Spiroacetal
Org Lett
(2005)
7
4121
(doi: 10.1021/ol051403c)
Towards the combinatorial synthesis of spongistatin fragment libraries by using asymmetric aldol reactions on solid support.
Chemical communications (Cambridge, England)
(2005)
3568
(doi: 10.1039/b505746a)
Development of a third-generation total synthesis of (+)-discodermolide: An expedient Still-Gennari-type fragment coupling utilizing an advanced beta-ketophosphonate
JOURNAL OF ORGANIC CHEMISTRY
(2005)
70
5494
(doi: 10.1021/jo0505481a)
The stereocontrolled total synthesis of altohyrtin A/spongistatin 1: The CD-spiroacetal segment
Organic & Biomolecular Chemistry
(2005)
3
2410
(doi: 10.1039/b504148a)