Total synthesis of (-)-reidispongiolide A, an actin-targeting marine macrolide.
I Paterson, K Ashton, R Britton, G Cecere, G Chouraqui, GJ Florence, J Stafford
Angewandte Chemie International Edition
(2007)
46
Total synthesis and stereochemical reassignment of (+)-dolastatin 19, a cytotoxic marine macrolide isolated from Dolabella auricularia
I Paterson, AD Findlay, GJ Florence
Tetrahedron
(2007)
63
Synthesis and biological evaluation of novel analogues of dictyostatin
I Paterson, NM Gardner, KG Poullennec, AE Wright
Bioorganic & Medicinal Chemistry Letters
(2007)
17
Synthesis of two diastereomeric C1–C22fragments of spirastrellolide A
I Paterson, EA Anderson, SM Dalby, J Genovino, JH Lim, C Moessner
Chemical Communications
(2007)
Design, synthesis and biological evaluation of a macrocyclic discodermolide/dictyostatin hybrid
I Paterson, NM Gardner
Chemical communications (Cambridge, England)
(2007)
The tubulin-bound conformation of discodermolide derived by NMR studies in solution supports a common pharmacophore model for epothilone and discodermolide.
VM Sánchez-Pedregal, K Kubicek, J Meiler, I Lyothier, I Paterson, T Carlomagno
Angewandte Chemie International Edition
(2006)
45
Synthesis of the DEF-bis-spiroacetal of spirastrellolide A exploiting a double asymmetric dihydroxylation/spiroacetalisation strategy.
I Paterson, EA Anderson, SM Dalby, JH Lim, P Maltas, C Moessner
Chem Commun (Camb)
(2006)
Synergistic effects of peloruside A and laulimalide with taxoid site drugs, but not with each other, on tubulin assembly
E Hamel, BW Day, JH Miller, MK Jung, PT Northcote, AK Ghosh, DP Curran, M Cushman, KC Nicolaou, I Paterson, EJ Sorensen
Molecular pharmacology
(2006)
70
Preparation of tritium‐labelled meta‐aminolevamisole of high specific radioactivity by catalytic dehalogenation
JA LEWIS, I PATERSON
Journal of Labelled Compounds and Radiopharmaceuticals
(2006)
21
Total Synthesis and Stereochemical Reassignment of (+)-Dolastatin 19
I Paterson, AD Findlay, GJ Florence
Organic letters
(2006)
8
Synthesis of novel 11-desmethyl analogues of laulimalide by Nozaki-Kishi coupling (vol 15, pg 2243, 2005)
I Paterson, H Bergmann, D Menche, A Berkessel
Organic Letters
(2006)
8
Synthesis of the C1-C21 southern hemisphere of the originally proposed structure of spirastrellolide a
I Paterson, EA Anderson, SM Dalby
Synthesis
(2005)
Microtubule interactions with chemically diverse stabilizing agents: Thermodynamics of binding to the paclitaxel site predicts cytotoxicity
RM Buey, I Barasoain, E Jackson, A Meyer, P Giannakakou, I Paterson, S Mooberry, JM Andreu, JF Díaz
Chem Biol
(2005)
12
The Renaissance of Natural Products as Drug Candidates
I Paterson, EA Anderson
Science
(2005)
310
Advances in the Total Synthesis of Biologically Important Marine Macrolides †
K-S Yeung, I Paterson
Chem Rev
(2005)
105
Toward the Synthesis of Spirastrellolide A:  Construction of Two C1−C25 Diastereomers Containing the BC−Spiroacetal
I Paterson, EA Anderson, SM Dalby, O Loiseleur
Organic Letters
(2005)
7
Toward the Synthesis of Spirastrellolide A:  Construction of a Tetracyclic C26−C40 Subunit Containing the DEF-Bis-Spiroacetal
I Paterson, EA Anderson, SM Dalby, O Loiseleur
Org Lett
(2005)
7
Towards the combinatorial synthesis of spongistatin fragment libraries by using asymmetric aldol reactions on solid support.
I Paterson, D Gottschling, D Menche
Chemical communications (Cambridge, England)
(2005)
Development of a third-generation total synthesis of (+)-discodermolide: An expedient Still-Gennari-type fragment coupling utilizing an advanced beta-ketophosphonate
I Paterson, I Lyothier
JOURNAL OF ORGANIC CHEMISTRY
(2005)
70
The stereocontrolled total synthesis of altohyrtin A/spongistatin 1: The CD-spiroacetal segment
I Paterson, MJ Coster, DY-K Chen, KR Gibson, DJ Wallace
Organic & Biomolecular Chemistry
(2005)
3