Studies toward a scalable second-generation total synthesis of the aplyronines as novel payloads for antibody-drug conjugates
– ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY
(2017)
253,
Towards the total synthesis and structural determination of patellazole B
– ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY
(2017)
253,
An Expedient Total Synthesis of Chivosazole F: an Actin-Binding Antimitotic Macrolide from the Myxobacterium $\textit{Sorangium Cellulosum}$
– Angew Chem Int Ed Engl
(2017)
56,
645
(DOI: 10.1002/anie.201610636)
Structural Determinants of the Dictyostatin Chemotype for Tubulin Binding Affinity and Antitumor Activity Against Taxane- and Epothilone-Resistant Cancer Cells.
– ACS omega
(2016)
1,
1192
(DOI: 10.1021/acsomega.6b00317)
Strategy Evolution in the Total Synthesis of (−)-Leiodermatolide
– Israel Journal of Chemistry
(2016)
57,
192
(DOI: 10.1002/ijch.201600084)
Evaluation of the brain-penetrant microtubule-stabilizing agent, dictyostatin, in the PS19 tau transgenic mouse model of tauopathy.
– Acta neuropathologica communications
(2016)
4,
106
(DOI: 10.1186/s40478-016-0378-4)
Toward the stereochemical assignment and synthesis of hemicalide: DP4f GIAO-NMR analysis and synthesis of a reassigned C16-C28 subunit
– Chemical communications (Cambridge, England)
(2016)
52,
4632
(DOI: 10.1039/c6cc01074a)
New substituted dictyostatin derivatives, useful for treating Alzheimer's disease, Parkinson's disease, Parkinson's disease with dementia, dementia with Lewy bodies, amyotrophic lateral sclerosis, and Huntington's disease in patient
(2015)
1,5-Antiselective aldol reactions for the total synthesis of the brasilinolides
– ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY
(2015)
250,
1,5-Anti selective aldol reactions for the total synthesis of the brasilinolides
– ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY
(2015)
249,
Total synthesis of leiodermatolide
– ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY
(2015)
249,
Synthetic studies toward the brasilinolides: controlled assembly of a protected C1-C38 polyol based on fragment union by complex aldol reactions.
– Organic & biomolecular chemistry
(2015)
13,
5716
(DOI: 10.1039/c5ob00498e)
Structural and Biochemical Studies of Actin in Complex with Synthetic Macrolide Tail Analogues
– ChemMedChem
(2014)
9,
2286
(DOI: 10.1002/cmdc.201402150)
Total synthesis of jiadifenolide
– Angew Chem Int Ed Engl
(2014)
53,
7286
(DOI: 10.1002/anie.201404224)
Molecular recognition of epothilones by microtubules and tubulin dimers revealed by biochemical and NMR approaches.
– ACS Chem Biol
(2014)
9,
1033
(DOI: 10.1021/cb400673h)
Total synthesis of the antimitotic marine macrolide (-)-leiodermatolide
– Angewandte Chemie (International ed. in English)
(2014)
53,
2692
(DOI: 10.1002/anie.201310164)
MT-stabilizer, dictyostatin, exhibits prolonged brain retention and activity: Potential therapeutic implications
– ACS Medicinal Chemistry Letters
(2013)
4,
886
(DOI: 10.1021/ml400233e)
The impact of the Mukaiyama aldol reaction in total synthesis.
– Angew Chem Int Ed Engl
(2013)
52,
9097
(DOI: 10.1002/anie.201303914)
Total synthesis of (+)-spirastrellolide A methyl ester: Challenges and discoveries
– Pure and Applied Chemistry
(2013)
85,
1133
(DOI: 10.1351/pac-con-13-01-01)