Studies toward a scalable second-generation total synthesis of the aplyronines as novel payloads for antibody-drug conjugates
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY
(2017)
253
Towards the total synthesis and structural determination of patellazole B
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY
(2017)
253
An Expedient Total Synthesis of Chivosazole F: an Actin-Binding Antimitotic Macrolide from the Myxobacterium $\textit{Sorangium Cellulosum}$
Angewandte Chemie (International ed. in English)
(2017)
56
645
(doi: 10.1002/anie.201610636)
Structural Determinants of the Dictyostatin Chemotype for Tubulin Binding Affinity and Antitumor Activity Against Taxane- and Epothilone-Resistant Cancer Cells.
ACS omega
(2016)
1
1192
(doi: 10.1021/acsomega.6b00317)
Strategy Evolution in the Total Synthesis of (−)‐Leiodermatolide
Israel Journal of Chemistry
(2016)
57
192
(doi: 10.1002/ijch.201600084)
Evaluation of the brain-penetrant microtubule-stabilizing agent, dictyostatin, in the PS19 tau transgenic mouse model of tauopathy.
Acta neuropathologica communications
(2016)
4
106
(doi: 10.1186/s40478-016-0378-4)
Toward the stereochemical assignment and synthesis of hemicalide: DP4f GIAO-NMR analysis and synthesis of a reassigned C16-C28 subunit.
Chemical communications (Cambridge, England)
(2016)
52
4632
(doi: 10.1039/c6cc01074a)
New substituted dictyostatin derivatives, useful for treating Alzheimer's disease, Parkinson's disease, Parkinson's disease with dementia, dementia with Lewy bodies, amyotrophic lateral sclerosis, and Huntington's disease in patient
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1,5-Antiselective aldol reactions for the total synthesis of the brasilinolides
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY
(2015)
250
1,5-Anti selective aldol reactions for the total synthesis of the brasilinolides
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY
(2015)
249
Total synthesis of leiodermatolide
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY
(2015)
249
Synthetic studies toward the brasilinolides: controlled assembly of a protected C1-C38 polyol based on fragment union by complex aldol reactions.
Organic & biomolecular chemistry
(2015)
13
5716
(doi: 10.1039/c5ob00498e)
Structural and Biochemical Studies of Actin in Complex with Synthetic Macrolide Tail Analogues
ChemMedChem
(2014)
9
2286
(doi: 10.1002/cmdc.201402150)
Molecular recognition of epothilones by microtubules and tubulin dimers revealed by biochemical and NMR approaches.
ACS Chem Biol
(2014)
9
1033
(doi: 10.1021/cb400673h)
Total synthesis of the antimitotic marine macrolide (-)-leiodermatolide
Angewandte Chemie (International ed. in English)
(2014)
53
2692
(doi: 10.1002/anie.201310164)
MT-stabilizer, dictyostatin, exhibits prolonged brain retention and activity: Potential therapeutic implications
ACS Medicinal Chemistry Letters
(2013)
4
886
(doi: 10.1021/ml400233e)
The impact of the Mukaiyama aldol reaction in total synthesis.
Angew Chem Int Ed Engl
(2013)
52
9097
(doi: 10.1002/anie.201303914)
Total synthesis of (+)-spirastrellolide A methyl ester: Challenges and discoveries
Pure and Applied Chemistry
(2013)
85
1133
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