Direct measurement of lipid membrane disruption connects kinetics and toxicity of A beta 42 aggregation
P Flagmeier, S De, TCT Michaels, X Yang, AJ Dear, C Emanuelsson, M Vendruscolo, S Linse, D Klenerman, TPJ Knowles, CM Dobson
– Nature structural & molecular biology
(2020)
27,
Phase Transition and Crystallization Kinetics of a Supramolecular System in a Microfluidic Platform
D Cohen-Gerassi, ZA Arnon, T Guterman, A Levin, M Ghosh, M Aviv, D Levy, TPJ Knowles, Y Shacham-Diamand, L Adler-Abramovich
– Chemistry of Materials
(2020)
32,
Continuous Flow Reactors from Microfluidic Compartmentalization of Enzymes within Inorganic Microparticles.
TA Hakala, F Bialas, Z Toprakcioglu, B Bräuer, KN Baumann, A Levin, GJL Bernardes, CFW Becker, TPJ Knowles
– ACS Appl Mater Interfaces
(2020)
12,
Half a century of amyloids: past, present and future.
PC Ke, R Zhou, LC Serpell, R Riek, TPJ Knowles, HA Lashuel, E Gazit, IW Hamley, TP Davis, M Fändrich, DE Otzen, MR Chapman, CM Dobson, DS Eisenberg, R Mezzenga
– Chemical Society Reviews
(2020)
49,
Multidimensional protein characterisation using microfluidic post-column analysis.
T Scheidt, T Kartanas, Q Peter, MM Schneider, KL Saar, T Müller, PK Challa, A Levin, S Devenish, TPJ Knowles
– Lab on A Chip
(2020)
20,
Infrared Nanospectroscopy Reveals the Molecular Interaction Fingerprint of an Aggregation Inhibitor with Single Aβ42 Oligomers
FS Ruggeri, J Habchi, S Chia, M Vendruscolo, T Knowles
(2020)
Templating S100A9 amyloids on Aβ fibrillar surfaces revealed by charge detection mass spectrometry, microscopy, kinetic and microfluidic analyses.
J Pansieri, IA Iashchishyn, H Fakhouri, L Ostojić, M Malisauskas, G Musteikyte, V Smirnovas, MM Schneider, T Scheidt, CK Xu, G Meisl, TPJ Knowles, E Gazit, R Antoine, LA Morozova-Roche
– Chemical science
(2020)
11,
Rational design of a conformation-specific antibody for the quantification of Aβ oligomers
FA Aprile, P Sormanni, M Podpolny, S Chhangur, L-M Needham, FS Ruggeri, M Perni, R Limbocker, GT Heller, T Sneideris, T Scheidt, B Mannini, J Habchi, SF Lee, PC Salinas, TPJ Knowles, CM Dobson, M Vendruscolo
– Proceedings of the National Academy of Sciences of the United States of America
(2020)
117,
Microfluidic Templating of Spatially Inhomogeneous Protein Microgels.
Y Xu, RPB Jacquat, Y Shen, D Vigolo, D Morse, S Zhang, TPJ Knowles
– Small (Weinheim an der Bergstrasse, Germany)
(2020)
16,
Single molecule secondary structure determination of proteins through infrared absorption nanospectroscopy.
FS Ruggeri, B Mannini, R Schmid, M Vendruscolo, TPJ Knowles
– Nature Communications
(2020)
11,
