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Yusuf Hamied Department of Chemistry

 

Research Associate

Publications

A library‐derived peptide inhibitor of the BZLF1 transcription factor
SK Madden, A Brennan, JM Mason
– J Pept Sci
(2023)
30,
e3557
DNA G‑Quadruplex Recognition In Vitro and in Live Cells by a Structure-Specific Nanobody
S Galli, L Melidis, SM Flynn, D Varshney, A Simeone, J Spiegel, SK Madden, D Tannahill, S Balasubramanian
– J Am Chem Soc
(2022)
144,
23096
Exploring the binding of rationally engineered tandem-repeat proteins to E3 ubiquitin ligase Keap1.
SK Madden, LS Itzhaki
– Protein Engineering, Design and Selection
(2021)
34,
gzab027
Taking the Myc out of cancer: toward therapeutic strategies to directly inhibit c-Myc.
SK Madden, AD de Araujo, M Gerhardt, DP Fairlie, JM Mason
– Molecular Cancer
(2021)
20,
3
Peptide library screening as a tool to derive potent therapeutics: current approaches and future strategies.
S K Madden
– Future medicinal chemistry
(2020)
13,
95
Structural and mechanistic insights into the Keap1-Nrf2 system as a route to drug discovery.
SK Madden, LS Itzhaki
– Biochimica et biophysica acta. Proteins and proteomics
(2020)
1868,
140405
Exploring new strategies for grafting binding peptides onto protein loops using a consensus‐designed tetratricopeptide repeat scaffold
SK Madden, A Perez-Riba, LS Itzhaki
– Protein Science
(2019)
28,
738
Highly selective inhibition of histone demethylases by de novo macrocyclic peptides
A Kawamura, M Münzel, T Kojima, C Yapp, B Bhushan, Y Goto, A Tumber, T Katoh, ONF King, T Passioura, LJ Walport, SB Hatch, S Madden, S Müller, PE Brennan, R Chowdhury, RJ Hopkinson, H Suga, CJ Schofield
– Nature Communications
(2017)
8,
14773
Studies on the catalytic domains of multiple JmjC oxygenases using peptide substrates.
ST Williams, LJ Walport, RJ Hopkinson, SK Madden, R Chowdhury, CJ Schofield, A Kawamura
– Epigenetics
(2015)
9,
1596
Human UTY(KDM6C) Is a Male-specific Nϵ-Methyl Lysyl Demethylase
LJ Walport, RJ Hopkinson, M Vollmar, SK Madden, C Gileadi, U Oppermann, CJ Schofield, C Johansson
– The Journal of biological chemistry
(2014)
289,
18302

Research Group

Telephone number

01223 762933 (shared)

Email address

skm53@cam.ac.uk