Research Associate

Publications

G-quadruplex DNA structure is a positive regulator of MYC transcription.
I Esain-Garcia, A Kirchner, L Melidis, RDCA Tavares, S Dhir, A Simeone, Z Yu, SK Madden, R Hermann, D Tannahill, S Balasubramanian
Proceedings of the National Academy of Sciences
(2024)
121
A library-derived peptide inhibitor of the BZLF1 transcription factor.
SK Madden, A Brennan, JM Mason
Journal of Peptide Science
(2023)
30
DNA G-Quadruplex Recognition In Vitro and in Live Cells by a Structure-Specific Nanobody.
S Galli, L Melidis, SM Flynn, D Varshney, A Simeone, J Spiegel, SK Madden, D Tannahill, S Balasubramanian
J Am Chem Soc
(2022)
144
Exploring the binding of rationally engineered tandem-repeat proteins to E3 ubiquitin ligase Keap1
SK Madden, LS Itzhaki
Protein Engineering, Design and Selection
(2021)
34
Taking the Myc out of cancer: toward therapeutic strategies to directly inhibit c-Myc
SK Madden, AD de Araujo, M Gerhardt, DP Fairlie, JM Mason
Molecular cancer
(2021)
20
Peptide library screening as a tool to derive potent therapeutics: current approaches and future strategies
S K Madden
Future Medicinal Chemistry
(2020)
13
Structural and mechanistic insights into the Keap1-Nrf2 system as a route to drug discovery.
SK Madden, LS Itzhaki
Biochim Biophys Acta Proteins Proteom
(2020)
1868
Exploring new strategies for grafting binding peptides onto protein loops using a consensus‐designed tetratricopeptide repeat scaffold
SK Madden, A Perez-Riba, LS Itzhaki
Protein science : a publication of the Protein Society
(2019)
28
Highly selective inhibition of histone demethylases by de novo macrocyclic peptides.
A Kawamura, M Münzel, T Kojima, C Yapp, B Bhushan, Y Goto, A Tumber, T Katoh, ONF King, T Passioura, LJ Walport, SB Hatch, S Madden, S Müller, PE Brennan, R Chowdhury, RJ Hopkinson, H Suga, CJ Schofield
Nat Commun
(2017)
8
Studies on the catalytic domains of multiple JmjC oxygenases using peptide substrates
ST Williams, LJ Walport, RJ Hopkinson, SK Madden, R Chowdhury, CJ Schofield, A Kawamura
Epigenetics
(2015)
9

Research Group

Telephone number

01223 762933 (shared)

Email address