In vivo translation rates can substantially delay the cotranslational folding of the Escherichia coli cytosolic proteome
P Ciryam, RI Morimoto, M Vendruscolo, CM Dobson, EP O'Brien
– Proc Natl Acad Sci U S A
(2012)
110,
A rationally designed six-residue swap generates comparability in the aggregation behavior of α-synuclein and β-synuclein
C Roodveldt, A Andersson, EJ De Genst, A Labrador-Garrido, AK Buell, CM Dobson, GG Tartaglia, M Vendruscolo
– Biochemistry
(2012)
51,
Twisting Transition between Crystalline and Fibrillar Phases of Aggregated Peptides
TPJ Knowles, A De Simone, AW Fitzpatrick, A Baldwin, S Meehan, L Rajah, M Vendruscolo, ME Welland, CM Dobson, EM Terentjev
– Physical review letters
(2012)
109,
JL Markley, H Akutsu, T Asakura, M Baldus, R Boelens, A Bonvin, R Kaptein, A Bax, I Bezsonova, MR Gryk, JC Hoch, DM Korzhnev, MW Maciejewski, D Case, WJ Chazin, TA Cross, S Dames, H Kessler, O Lange, T Madl, B Reif, M Sattler, D Eliezer, A Fersht, J Forman-Kay, LE Kay, J Fraser, J Gross, T Kortemme, A Sali, T Fujiwara, K Gardner, X Luo, J Rizo-Rey, M Rosen, RR Gil, C Ho, G Rule, AM Gronenborn, R Ishima, J Klein-Seetharaman, P Tang, P van der Wel, Y Xu, S Grzesiek, S Hiller, J Seelig, ED Laue, H Mott, D Nietlispach, I Barsukov, L-Y Lian, D Middleton, T Blumenschein, G Moore, I Campbell, J Schnell, IJ Vakonakis, A Watts, MR Conte, J Mason, M Pfuhl, MR Sanderson, J Craven, M Williamson, C Dominguez, G Roberts, U Günther, M Overduin, J Werner, P Williamson, C Blindauer, M Crump, P Driscoll, T Frenkiel, A Golovanov, S Matthews, J Parkinson, D Uhrin, M Williams, D Neuhaus, H Oschkinat, A Ramos, DE Shaw, C Steinbeck, M Vendruscolo, GW Vuister, KJ Walters, H Weinstein, K Wüthrich, S Yokoyama
– Nature Structural & Molecular Biology
(2012)
19,
From macroscopic measurements to microscopic mechanisms of protein aggregation
SIA Cohen, M Vendruscolo, CM Dobson, TPJ Knowles
– Journal of Molecular Biology
(2012)
421,
Sequence-based prediction of protein solubility
F Agostini, M Vendruscolo, GG Tartaglia
– Journal of Molecular Biology
(2012)
421,
ADP ribosylation adapts an ER chaperone response to short-term fluctuations in unfolded protein load
JE Chambers, K Petrova, G Tomba, M Vendruscolo, D Ron
– The Journal of cell biology
(2012)
198,
Determination of structural fluctuations of proteins from structure-based calculations of residual dipolar couplings
RW Montalvao, A De Simone, M Vendruscolo
– Journal of Biomolecular NMR
(2012)
53,
Determination of structural fluctuations of proteins from structure-based calculations of residual dipolar couplings
RW Montalvao, A De Simone, M Vendruscolo
– Journal of biomolecular NMR
(2012)
53,
Trigger factor slows Co-translational folding through kinetic trapping while sterically protecting the nascent chain from aberrant cytosolic interactions
EP O'Brien, J Christodoulou, M Vendruscolo, CM Dobson
– J Am Chem Soc
(2012)
134,