skip to content
Home

Yusuf Hamied Department of Chemistry

 

Dr Joe Beckwith

Assistant Research Professor

Publications

Large-scale visualization of α-synuclein oligomers in Parkinson's disease brain tissue.
R Andrews, B Fu, CE Toomey, JC Breiter, J Lachica, JS Beckwith, R Tian, EE Brock, L-M Needham, GJ Chant, C Loiseau, A Deconfin, K Baspin, R Popovic, J Evans, Y Goh, B Kurt, L Senicar, M Edmonds, T Bartels, N Bengoa-Vergniory, PJ Magill, Z Jaunmuktane, OJ Freeman, BJM Taylor, J Hardy, T Lashley, M Ryten, M Vendruscolo, NW Wood, LE Weiss, S Gandhi, SF Lee
– Nature biomedical engineering
(2025)
1
(doi: 10.1038/s41551-025-01496-4)
Neurodegeneration emerges at a cellular tipping point between aggregate accumulation and removal
MW Cotton, S Venkatesan, JS Beckwith, D Böken, CK Xu, JC Breiter, LE Berkowicz, LS Salazar, A Von Schulze, EA Andrzejewska, EE Brock, HL Han, MM Schneider, DD Sahtoe, D Baker, JB Rowe, A Goriely, WA McEwan, TPJ Knowles, SF Lee, R Halfmann, D Klenerman, G Meisl
(2025)
(doi: 10.1101/2025.09.08.674880)
Microglial activation and alpha-synuclein oligomers drive the early inflammatory phase of Parkinson’s disease
J Evans, M Grant-Peters, J Beckwith, C Toomey, R Popovic, J Breiter, J Brenton, A Fairbrother-Browne, S Strohbuecker, J Lachica, M Rodriguez-Lopez, E Brock, B Fu, L Nahidiazar, P Lopez-Garcia, R Ferguson, R Saleeb, H Lucas-Clarke, A Penverne, K D’Sa, CW Pang, M Horrocks, M Vendruscolo, N Wood, S Lee, M Ryten, S Gandhi
(2025)
(doi: 10.1101/2025.08.25.671921)
α-Synuclein driven cell susceptibility in Parkinson’s disease
J Breiter, J Beckwith, E Brock, J Lachica, C Toomey, B Fu, M Ryten, L Weiss, N Wood, S Gandhi, M Vendruscolo, S Lee
(2025)
(doi: 10.1101/2025.08.19.670819)
Volumetric single-molecule tracking inside subcellular structures
S Daly, J Chambers, C Jones, B Fu, J Manton, J Beckwith, S Marciniak, D Gershlick, S Lee
(2025)
(doi: 10.1101/2025.06.09.658280)
RASP: Optimal Single Puncta Detection in Complex Cellular Backgrounds.
B Fu, E Brock, R Andrews, J Breiter, R Tian, C Toomey, J Lachica, T Lashley, M Ryten, N Wood, M Vendruscolo, S Gandhi, L Weiss, J Beckwith, S Lee
– Journal of Physical Chemistry B
(2024)
128,
3585
(doi: 10.1021/acs.jpcb.4c00174)
High-density volumetric super-resolution microscopy.
S Daly, J Ferreira Fernandes, E Bruggeman, A Handa, R Peters, S Benaissa, B Zhang, JS Beckwith, EW Sanders, RR Sims, D Klenerman, SJ Davis, K O'Holleran, SF Lee
– Nature communications
(2024)
15,
1940
(doi: 10.1038/s41467-024-45828-5)
High-density volumetric super-resolution microscopy
S Daly, J Ferreira Fernandes, E Bruggeman, A Handa, R Peters, S Benaissa, B Zhang, JS Beckwith, EW Sanders, RR Sims, D Klenerman, SJ Davis, K O’Holleran, SF Lee
– Nature Communications
(2024)
15,
1940
(doi: 10.1038/s41467-024-45828-5)
Large-scale visualisation of α-synuclein oligomers in Parkinson's disease brain tissue
R Andrews, B Fu, C Toomey, J Breiter, J Lachica, R Tian, J Beckwith, L-M Needham, G Chant, C Loiseau, A Deconfin, K Baspin, P Magill, Z Jaunmuktane, O Freeman, BJM Taylor, J Hardy, T Lashley, M Ryten, M Vendruscolo, N Wood, L Weiss, S Gandhi, S Lee
(2024)
(doi: 10.1101/2024.02.17.580698)
RASP: Optimal single fluorescent puncta detection in complex cellular backgrounds
B Fu, E Brock, R Andrews, J Breiter, R Tian, C Toomey, J Lachica, T Lashley, M Ryten, N Wood, M Vendruscolo, S Gandhi, L Weiss, J Beckwith, S Lee
(2023)
(doi: 10.1101/2023.12.18.572148)
  • 1 of 3
  • >

Research Group

Email address

jsb92@cam.ac.uk

College

Sidney Sussex College

    Study at Cambridge

    About the University

    Research at Cambridge