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  • Currently displaying 81 - 100 of 229 publications
Poly(ADP-Ribose) Links the DNA Damage Response and Biomineralization
K Mueller
– Cell reports
(2019)
27,
3124
(doi: 10.1016/j.celrep.2019.05.038)
Different soluble aggregates of Aβ42 can give rise to cellular toxicity through different mechanisms
S De, DC Wirthensohn, P Flagmeier, C Hughes, FA Aprile, FS Ruggeri, DR Whiten, D Emin, Z Xia, JA Varela, P Sormanni, F Kundel, TPJ Knowles, CM Dobson, C Bryant, M Vendruscolo, D Klenerman
– Nat Commun
(2019)
10,
1541
(doi: 10.1038/s41467-019-09477-3)
Modular actin nano-architecture enables podosome protrusion and mechanosensing
K van den Dries, L Nahidiazar, JA Slotman, MBM Meddens, E Pandzic, B Joosten, M Ansems, J Schouwstra, A Meijer, R Steen, M Wijers, J Fransen, AB Houtsmuller, PW Wiseman, K Jalink, A cambi
(2019)
(doi: 10.1101/583492)
Spectrally-Resolved Photodynamics Of Individual Emitters In Large-Area Monolayers Of Hexagonal-Boron Nitride.
HL Stern, R Wang, Y Fan, R Mizuta, JC Stewart, L-M Needham, TD Roberts, R Wai, NS Ginsberg, D Klenerman, S Hofmann, SF Lee
– ACS Nano
(2019)
13,
4538
(doi: 10.1021/acsnano.9b00274)
Spectrally-Resolved Photodynamics of Individual Emitters in Large-Area Monolayers of Hexagonal-Boron Nitride
HL Stern, R Wang, Y Fan, R Mizuta, JC Stewart, L-M Needham, TD Roberts, R Wai, NS Ginsberg, D Klenerman, S Hofmann, SF Lee
(2019)
(doi: 10.48550/arxiv.1901.02793)
Mapping Surface Hydrophobicity of α‑Synuclein Oligomers at the Nanoscale
J-E Lee, JC Sang, M Rodrigues, AR Carr, MH Horrocks, S De, MN Bongiovanni, P Flagmeier, CM Dobson, DJ Wales, SF Lee, D Klenerman
– Nano Lett
(2018)
18,
7494
(doi: 10.1021/acs.nanolett.8b02916)
Machine Learning for Analysis of Time-Resolved Luminescence Data
N Dordević, JS Beckwith, M Yarema, O Yarema, A Rosspeintner, N Yazdani, J Leuthold, E Vauthey, V Wood
– ACS Photonics
(2018)
5,
4888
(doi: 10.1021/acsphotonics.8b01047)
Mechanisms of integrin αVβ5 clustering in flat clathrin lattices.
A Zuidema, W Wang, M Kreft, L Te Molder, L Hoekman, OB Bleijerveld, L Nahidiazar, H Janssen, A Sonnenberg
– Journal of Cell Science
(2018)
131,
jcs221317
(doi: 10.1242/jcs.221317)
Sensitive light-sheet microscopy in multiwell plates using an AFM cantilever
A Ponjavic, Y Ye, E Laue, SF Lee, D Klenerman
– Biomed Opt Express
(2018)
9,
5863
(doi: 10.1364/BOE.9.005863)
Profilin binding couples chloride intracellular channel protein CLIC4 to RhoA–mDia2 signaling and filopodium formation
E Argenzio, J Klarenbeek, KM Kedziora, L Nahidiazar, T Isogai, A Perrakis, K Jalink, WH Moolenaar, M Innocenti
– J Biol Chem
(2018)
293,
19161
(doi: 10.1074/jbc.ra118.002779)
Nanoscopic characterization of individual endogenous protein aggregates in human neuronal cells
DR Whiten, Y Zuo, L Calo, M-L Choi, S De, P Flagmeier, DC Wirthensohn, F Kundel, RT Ranasinghe, SE Sanchez, D Athauda, SF Lee, CM Dobson, S Gandhi, M-G Spillantini, D Klenerman, MH Horrocks
– Chembiochem : a European journal of chemical biology
(2018)
19,
2033
(doi: 10.1002/cbic.201800209)
Extrinsic Amyloid-Binding Dyes for Detection of Individual Protein Aggregates in Solution.
D Klenerman
– Analytical chemistry
(2018)
90,
10385
(doi: 10.1021/acs.analchem.8b02226)
Fabrication of scaffold-based 3D magnetic nanowires for domain wall applications
D Sanz-Hernández, RF Hamans, J Osterrieth, J-W Liao, L Skoric, JD Fowlkes, PD Rack, A Lippert, SF Lee, R Lavrijsen, A Fernández-Pacheco
– Nanomaterials (Basel)
(2018)
8,
483
(doi: 10.3390/nano8070483)
Analysis of nanobody paratopes reveals greater diversity than classical antibodies.
LS Mitchell, LJ Colwell
– Protein Engineering Design and Selection
(2018)
31,
267
(doi: 10.1093/protein/gzy017)
FRET-enhanced photostability allows improved single-molecule tracking of proteins and protein complexes in live mammalian cells
S Basu, L-M Needham, D Lando, EJR Taylor, KJ Wohlfahrt, D Shah, W Boucher, YL Tan, LE Bates, O Tkachenko, J Cramard, BC Lagerholm, C Eggeling, B Hendrich, D Klenerman, SF Lee, ED Laue
– Nature Communications
(2018)
9,
2520
(doi: 10.1038/s41467-018-04486-0)
Single-Molecule Characterization of the Interactions between Extracellular Chaperones and Toxic α-Synuclein Oligomers.
DR Whiten, D Cox, MH Horrocks, CG Taylor, S De, P Flagmeier, L Tosatto, JR Kumita, H Ecroyd, CM Dobson, D Klenerman, MR Wilson
– Cell Reports
(2018)
23,
3492
(doi: 10.1016/j.celrep.2018.05.074)
α-synuclein oligomers interact with ATP synthase and open the permeability transition pore in Parkinson’s disease
MHR Ludtmann, PR Angelova, MH Horrocks, ML Choi, M Rodrigues, AY Baev, AV Berezhnov, Z Yao, D Little, B Banushi, AS Al-Menhali, RT Ranasinghe, DR Whiten, R Yapom, KS Dolt, MJ Devine, P Gissen, T Kunath, M Jaganjac, EV Pavlov, D Klenerman, AY Abramov, S Gandhi
– Nature communications
(2018)
9,
2293
(doi: 10.1038/s41467-018-04422-2)
A sticky situation: Aberrant protein-protein interactions in Parkinson's disease.
J Brown, MH Horrocks
– Semin Cell Dev Biol
(2018)
99,
65
(doi: 10.1016/j.semcdb.2018.05.006)
Single-Molecule Light-Sheet Imaging of Suspended T Cells.
A Ponjavic, J McColl, AR Carr, AM Santos, K Kulenkampff, A Lippert, SJ Davis, D Klenerman, SF Lee
– Biophysical Journal
(2018)
114,
2200
(doi: 10.1016/j.bpj.2018.02.044)
Phase Separation of FUS is Modulated by Methylation State of Cation-π Interactions and Interaction with TNPO1
PH St George-Hyslop, S Qamar, G Wang, SJ Randle, FS Ruggeri, J Varela, CF Kaminski, GS Kaminski, M Vendruscolo, TPJ Knowles, D Klenerman, CE Holt, Q Lin, W meadows
– Cell
(2018)
(doi: 10.1016/j.cell.2018.03.056)

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