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Method development

We like to build microscopes, take them apart and use them in a way they weren’t intended to. Then we measure the properties of individual fluorescent molecules.

By looking at cells one at a time, we can determine where they are in a space to a high degree. However, there is more information contained within that light that we try to use to tell us more about the environment the probe is in. This process is called multi-dimensional super-resolution imaging.

These new instruments help us understand questions like:

  • how does your body deal with new infection
  • why you get cancer
  • where in your brain Parkinson’s disease resides

Our method development work spans three key topics:

  1. 3D super-resolution microscopy
  2. New dye development
  3. Multi-dimensional super-resolution microscopy

You can read more about these research areas using the panel on the right-hand side.