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  • Currently displaying 1 - 20 of 229 publications
The Origin of Single-Molecule Sensitivity in Label-Free Solution-Phase Optical Microcavity Detection
CA Saavedra Salazar, D Sole-Barber, S Wan, JK Rasch, M Reitz, B Cullinane, N Asgari, L-M Needham, J Yuen-Zhou, RH Goldsmith
– ACS Nano
(2025)
19,
6342
(doi: 10.1021/acsnano.4c16276)
3D Super-Resolution Imaging of PSD95 Reveals an Abundance of Diffuse Protein Supercomplexes in the Mouse Brain
S Daly, E Bulovaite, A Handa, K Morris, L Muresan, C Adams, T Kaizuka, A Kitching, A Spark, G Chant, K O Holleran, SGN Grant, MH Horrocks, SF Lee
– ACS chemical neuroscience
(2024)
16,
40
(doi: 10.1021/acschemneuro.4c00684)
Vortex light field microscopy: 3D spectral single-molecule imaging with a twist
B Zhang, S Daly, C Zhu, MO Lenz, LE Weiss, LM Needham, R Peters, SF Lee, K O’Holleran
– Optica
(2024)
11,
1519
(doi: 10.1364/optica.534148)
3D super-resolution imaging of PSD95 reveals an abundance of diffuse protein supercomplexes in the mouse brain
S Daly, E Bulovaite, A Handa, K Morris, L Muresan, C Adams, T Kaizuka, A Kitching, A Spark, G Chant, K O’Holleran, S Grant, M Horrocks, S Lee
(2024)
(doi: 10.1101/2024.10.14.617231)
POLCAM: Instant molecular orientation microscopy for the life sciences
E Bruggeman, O Zhang, L-M Needham, M Körbel, S Daly, M Cheetham, R Peters, T Wu, AS Klymchenko, SJ Davis, EK Paluch, D Klenerman, MD Lew, K O'Holleran, SF Lee
– Nat Methods
(2024)
21,
1873
(doi: 10.1038/s41592-024-02382-8)
Single-Molecule Sensitivity in Hot Microcavities in the Unstable Regime
CA Saavedra Salazar, D Sole-Barber, N Asgari, B Cullinane, L-M Needham, J Rasch, M Reitz, S Wan, J Yuen-Zhou, R Goldsmith
(2024)
(doi: 10.26434/chemrxiv-2024-xgtxg)
Single-molecule digital sizing of proteins in solution.
G Krainer, RPB Jacquat, MM Schneider, TJ Welsh, J Fan, QAE Peter, EA Andrzejewska, G Šneiderienė, MA Czekalska, H Ausserwoeger, L Chai, WE Arter, KL Saar, TW Herling, TM Franzmann, V Kosmoliaptsis, S Alberti, FU Hartl, SF Lee, TPJ Knowles
– Nat Commun
(2024)
15,
7740
(doi: 10.1038/s41467-024-50825-9)
Vortex light field microscopy: 3D spectral single-molecule imaging with a twist
B Zhang, S Daly, C Zhu, MO Lenz, LE Weiss, L-M Needham, R Peters, SF Lee, K O’Holleran
(2024)
(doi: 10.1101/2024.07.18.604091)
Advances in volumetric super-resolution microscopy and single-particle tracking
S Daly
(2024)
(doi: 10.17863/CAM.113698)
Single-Molecule Stoichiometry of Supramolecular Complexes.
A McLean, RL Sala, BW Longbottom, AR Carr, JA McCune, SF Lee, OA Scherman
– J Am Chem Soc
(2024)
146,
12877
(doi: 10.1021/jacs.4c00611)
dSTORM of actin in fixed HeLa cells v1
E Bruggeman, R peters
(2024)
(doi: 10.17504/protocols.io.q26g714j8gwz/v1)
Live-cell imaging of the plasma membrane of Jurkat T cells v1
E Bruggeman, M Körbel
(2024)
(doi: 10.17504/protocols.io.kxygxyzxzl8j/v1)
Preparation and imaging of lipid bilayer-coated silica microspheres v1
E Bruggeman
(2024)
(doi: 10.17504/protocols.io.rm7vzjy2rlx1/v1)
Label-free detection and profiling of individual solution-phase molecules.
L-M Needham, C Saavedra, JK Rasch, D Sole-Barber, BS Schweitzer, AJ Fairhall, CH Vollbrecht, S Wan, Y Podorova, AJ Bergsten, B Mehlenbacher, Z Zhang, L Tenbrake, J Saimi, LC Kneely, JS Kirkwood, H Pfeifer, ER Chapman, RH Goldsmith
– Nature
(2024)
629,
1062
(doi: 10.1038/s41586-024-07370-8)
RASP: Optimal Single Puncta Detection in Complex Cellular Backgrounds
B Fu, E Brock, R Andrews, J Breiter, R Tian, C Toomey, J Lachica, T Lashley, M Ryten, N Wood, M Vendruscolo, S Gandhi, L Weiss, J Beckwith, S Lee
– The journal of physical chemistry. B
(2024)
128,
3585
(doi: 10.1021/acs.jpcb.4c00174)
Development of Novel Labelling Strategies for Imaging in Nanoscale Topography
E Sanders
(2024)
(doi: 10.17863/CAM.111799)
Single-molecule orientation estimation using a polarisation camera
E Bruggeman
(2024)
(doi: 10.17863/CAM.112690)
High-density volumetric super-resolution microscopy
S Daly, J Ferreira Fernandes, E Bruggeman, A Handa, R Peters, S Benaissa, B Zhang, JS Beckwith, EW Sanders, RR Sims, D Klenerman, SJ Davis, K O'Holleran, SF Lee
– Nat Commun
(2024)
15,
1940
(doi: 10.1038/s41467-024-45828-5)
High-density volumetric super-resolution microscopy
S Daly, J Ferreira Fernandes, E Bruggeman, A Handa, R Peters, S Benaissa, B Zhang, JS Beckwith, EW Sanders, RR Sims, D Klenerman, SJ Davis, K O’Holleran, SF Lee
– Nature Communications
(2024)
15,
1940
(doi: 10.1038/s41467-024-45828-5)
Large-scale visualisation of α-synuclein oligomers in Parkinson's disease brain tissue
R Andrews, B Fu, C Toomey, J Breiter, J Lachica, R Tian, J Beckwith, L-M Needham, G Chant, C Loiseau, A Deconfin, K Baspin, P Magill, Z Jaunmuktane, O Freeman, BJM Taylor, J Hardy, T Lashley, M Ryten, M Vendruscolo, N Wood, L Weiss, S Gandhi, S Lee
(2024)
(doi: 10.1101/2024.02.17.580698)

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