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  • Currently displaying 21 - 40 of 199 publications
ThX: a next generation probe for the early detection of amyloid aggregates
L-M Needham, J Weber, JA Varela, JWB Fyfe, DT Do, CK Xu, D Klenerman, CM Dobson, CA Hunter, SE Bohndiek, TN Snaddon, SF Lee
– Biophysical Journal
(2022)
121,
19a
(doi: 10.1016/j.bpj.2021.11.2608)
Imaging T-cell activation: topography and features of early T-cell contacts
M Korbel, E Jenkins, JT McColl, C O'Brien-Ball, AH Lippert, AM Santos, SF Lee, SJ Davis, D Klenerman
– Biophysical Journal
(2022)
121,
150A
(doi: 10.1016/j.bpj.2021.11.1976)
(link to publication)
Room-temperature optically detected magnetic resonance of single defects in hexagonal boron nitride.
HL Stern, J Jarman, Q Gu, SE Barker, N Mendelson, D Chugh, S Schott, HH Tan, H Sirringhaus, I Aharonovich, M Atatüre
– Nature Communications
(2022)
13,
618
(doi: 10.1038/s41467-022-28169-z)
A Comparative Study of High-Contrast Fluorescence Lifetime Probes for Imaging Amyloid in Tissue
F Gorka, CM Pearson, E Bulovaite, YP Zhang, A Handa, SGN Grant, TN Snaddon, LM Needham, SF Lee
– The Journal of Physical Chemistry B: Biophysical Chemistry, Biomaterials, Liquids, and Soft Matter
(2021)
(doi: 10.1021/acs.jpcb.1c07762)
The excited-state dynamics of the radical anions of cyanoanthracenes
JS Beckwith, A Aster, E Vauthey
– Physical chemistry chemical physics : PCCP
(2021)
24,
568
(doi: 10.1039/d1cp04014f)
A Comparative Study of High-Contrast Fluorescence Lifetime Probes for Imaging Amyloid in Tissue
F Gorka, S Daly, CM Pearson, E Bulovaite, YP Zhang, A Handa, SGN Grant, TN Snaddon, L-M Needham, SF Lee
– Journal of Physical Chemistry B
(2021)
125,
13710
(doi: 10.1021/acs.jpcb.1c07762)
Sub-millisecond Translational and Orientational Dynamics of a Freely Moving Single Nanoprobe
JS Beckwith, H Yang
– Journal of Physical Chemistry B
(2021)
125,
13436
(doi: 10.1021/acs.jpcb.1c08917)
Leveraging lifetime information to perform real-time 3D single-particle tracking in noisy environments
T Zhao, JS Beckwith, MJ Amin, M Pálmai, PT Snee, M Tien, H Yang
– The Journal of chemical physics
(2021)
155,
164201
(doi: 10.1063/5.0063634)
Information bounds in determining the 3D orientation of a single emitter or scatterer using point-detector-based division-of-amplitude polarimetry.
JS Beckwith, H Yang
– The Journal of Chemical Physics
(2021)
155,
144110
(doi: 10.1063/5.0065034)
Excited-state Dynamics of Radical Ions in Liquids
J Grilj, JS Beckwith, E Vauthey
– Chimia
(2021)
75,
856
(doi: 10.2533/chimia.2021.856)
Quantum Emitter Localization in Layer-Engineered Hexagonal Boron Nitride
JC Stewart, Y Fan, JSH Danial, A Goetz, AS Prasad, OJ Burton, JA Alexander-Webber, SF Lee, SM Skoff, V Babenko, S Hofmann
– ACS Nano
(2021)
15,
13591
(doi: 10.1021/acsnano.1c04467)
Wild-type sTREM2 blocks Aβ aggregation and neurotoxicity, but the Alzheimer’s R47H mutant increases Aβ aggregation
A Vilalta, Y Zhou, J Sevalle, JK Griffin, K Satoh, DH Allendorf, S De, M Puigdellívol, A Bruzas, MA Burguillos, RB Dodd, F Chen, Y Zhang, P Flagmeier, L-M Needham, M Enomoto, S Qamar, J Henderson, J Walter, PE Fraser, D Klenerman, SF Lee, P St George-Hyslop, GC Brown
– Journal of Biological Chemistry
(2021)
296,
100631
(doi: 10.1016/j.jbc.2021.100631)
Two RuII Linkage Isomers with Distinctly Different Charge Transfer Photophysics.
J Tisaun, B Laramée-Milette, JS Beckwith, J Bierwagen, GS Hanan, C Reber, A Hauser, C Moucheron
– Inorganic Chemistry
(2021)
60,
3677
(doi: 10.1021/acs.inorgchem.0c03371)
Multicolor Localization-Based Super Resolution Microscopy.
L Nahidiazar, R Harkes
(2021)
2350,
69
(doi: 10.1007/978-1-0716-1593-5_5)
Single-molecule fluorescence detection of a tricyclic nucleoside analogue.
GN Samaan, MK Wyllie, JM Cizmic, L-M Needham, D Nobis, K Ngo, S Andersen, SW Magennis, SF Lee, BW Purse
– Chemical science
(2020)
12,
2623
(doi: 10.1039/d0sc03903a)
Wild-type sTREM2 blocks Aβ aggregation and neurotoxicity, while the Alzheimer’s R47H mutant does the opposite
A Vilalta, Y Zhou, J Sevalle, JK Griffin, K Satoh, DH Allendorf, S De, M Puigdellívol, A Bruzas, MA Burguillos, RB Dodd, F Chen, Y Zhang, P Flagmeier, L-M Needham, M Enomoto, S Qamar, J Henderson, J Walter, PE Fraser, D Klenerman, SF Lee, P St George-Hyslop, GC Brown
(2020)
(doi: 10.1101/2020.12.03.409995)
vLUME: 3D virtual reality for single-molecule localization microscopy
A Spark, A Kitching, D Esteban-Ferrer, A Handa, AR Carr, L-M Needham, A Ponjavic, AM Santos, J McColl, C Leterrier, SJ Davis, R Henriques, SF Lee
– Nature Methods
(2020)
17,
1097
(doi: 10.1038/s41592-020-0962-1)
A Comparative Photophysical Study of Structural Modifications of Thioflavin T-Inspired Fluorophores
L-M Needham, J Weber, CM Pearson, DT Do, F Gorka, G Lyu, SE Bohndiek, TN Snaddon, SF Lee
– The journal of physical chemistry letters
(2020)
11,
8406
(doi: 10.1021/acs.jpclett.0c01549)
Single Molecule Light Field Microscopy
RR Sims, SA Rehman, MO Lenz, SI Benaissa, E Bruggeman, A Clark, EW Sanders, A Ponjavic, L Muresan, SF Lee, K O’Holleran
– Optica
(2020)
7,
1065
(doi: 10.1364/optica.397172)
Single-molecule visualization of DNA G-quadruplex formation in live cells
M Di Antonio, A Ponjavic, A Radzevičius, RT Ranasinghe, M Catalano, X Zhang, J Shen, L-M Needham, SF Lee, D Klenerman, S Balasubramanian
– Nature Chemistry
(2020)
12,
832
(doi: 10.1038/s41557-020-0506-4)

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