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  • Currently displaying 41 - 60 of 201 publications
Single molecule light field microscopy
RR Sims, SA Rehman, MO Lenz, SI Benaissa, E Bruggeman, A Clark, EW Sanders, A Ponjavic, L Muresan, SF Lee, K O’Holleran
– Optica
(2020)
7,
1065
(doi: 10.1364/OPTICA.397172)
Single-molecule visualisation of DNA G-quadruplex formation in live cells.
M Di Antonio, A Ponjavic, A Radzevičius, RT Ranasinghe, M Catalano, X Zhang, J Shen, L-M Needham, SF Lee, D Klenerman, S Balasubramanian
– Nature chemistry
(2020)
12,
832
(doi: 10.1038/s41557-020-0506-4)
Rational design of a conformation-specific antibody for the quantification of Aβ oligomers
FA Aprile, P Sormanni, M Podpolny, S Chhangur, L-M Needham, FS Ruggeri, M Perni, R Limbocker, GT Heller, T Sneideris, T Scheidt, B Mannini, J Habchi, SF Lee, PC Salinas, TPJ Knowles, CM Dobson, M Vendruscolo
– Proc Natl Acad Sci U S A
(2020)
117,
13509
(doi: 10.1073/pnas.1919464117)
Data analysis in transient electronic spectroscopy – an experimentalist's view
JS Beckwith, CA Rumble, E Vauthey
– International Reviews in Physical Chemistry
(2020)
39,
135
(doi: 10.1080/0144235x.2020.1757942)
Single Molecule Light Field Microscopy
R Sims, S Abdul Rehman, M Lenz, A Clark, E Sanders, A Ponjavic, L Muresan, S Lee, K O’Holleran
(2020)
2020.05.20.104802
(doi: 10.1101/2020.05.20.104802)
ThX-a next-generation probe for the early detection of amyloid aggregates
L-M Needham, J Weber, JA Varela, JWB Fyfe, DT Do, CK Xu, L Tutton, R Cliffe, B Keenlyside, D Klenerman, CM Dobson, CA Hunter, KH Müller, K O'Holleran, SE Bohndiek, TN Snaddon, SF Lee
– Chem Sci
(2020)
11,
4578
(doi: 10.1039/c9sc04730a)
Live-cell 3D single-molecule tracking reveals how NuRD modulates enhancer dynamics
S Basu, O Shukron, D Hall, D Hall, P Parruto, A Ponjavic, D Shah, W Boucher, D Lando, W Zhang, N Reynolds, L Sober, A Jartseva, R Ragheb, X Ma, J Cramard, R Floyd, G Brown, J Balmer, T Drury, A Carr, L-M Needham, A Aubert, G Communie, K Gor, M Steindel, L Morey, E Blanco, T Bartke, L Di Croce, I Berger, C Schaffitzel, S Lee, T Stevens, D Klenerman, B Hendrich, D Holcman, E Laue
– BioRxiv
(2020)
2020.04.03.003178
(doi: 10.1101/2020.04.03.003178)
The Costs of Close Contacts: Visualizing the Energy Landscape of Cell Contacts at the Nanoscale
K Kulenkampff, AH Lippert, J McColl, AM Santos, A Ponjavic, E Jenkins, J Humphrey, A Winkel, K Franze, SF Lee, SJ Davis, D Klenerman
– Biophys J
(2020)
118,
1261
(doi: 10.1016/j.bpj.2020.01.019)
vLUME: 3D Virtual Reality for Single-molecule Localization Microscopy
A Spark, A Kitching, D Esteban-Ferrer, A Handa, A Carr, L-M Needham, A Ponjavic, MDC Santos, J McColl, C Leterrier, S Davis, R Henriques, S Lee
(2020)
2020.01.20.912733
(doi: 10.1101/2020.01.20.912733)
Hemidesmosomes modulate force generation via focal adhesions.
W Wang, A Zuidema, L Te Molder, L Nahidiazar, L Hoekman, T Schmidt, S Coppola, A Sonnenberg
– Journal of Cell Biology
(2020)
219,
e201904137
(doi: 10.1083/jcb.201904137)
Modular actin nano-architecture enables podosome protrusion and mechanosensing
K van den Dries, L Nahidiazar, JA Slotman, MBM Meddens, E Pandzic, B Joosten, M Ansems, J Schouwstra, A Meijer, R Steen, M Wijers, J Fransen, AB Houtsmuller, PW Wiseman, K Jalink, A Cambi
– Nat Commun
(2019)
10,
5171
(doi: 10.1038/s41467-019-13123-3)
ThX: a next generation probe for the early detection of amyloid aggregates
L-M Needham, J Weber, JA Varela, JWB Fyfe, DT Do, CK Xu, D Klenerman, CM Dobson, CA Hunter, SE Bohndiek, TN Snaddon, SF Lee
– BIOPHYSICAL JOURNAL
(2019)
121,
713594
(doi: 10.1101/713594)
A cell topography-based mechanism for ligand discrimination by the T cell receptor.
RA Fernandes, KA Ganzinger, JC Tzou, P Jönsson, SF Lee, M Palayret, AM Santos, AR Carr, A Ponjavic, VT Chang, C Macleod, BC Lagerholm, AE Lindsay, O Dushek, A Tilevik, SJ Davis, D Klenerman
– Proceedings of the National Academy of Sciences
(2019)
116,
14002
(doi: 10.1073/pnas.1817255116)
Ion-Pair Dynamics upon Photoinduced Electron Transfer Monitored by Pump-Pump-Probe Spectroscopy.
JS Beckwith, B Lang, J Grilj, E Vauthey
– The Journal of Physical Chemistry Letters
(2019)
10,
3688
(doi: 10.1021/acs.jpclett.9b01431)
Poly(ADP-Ribose) Links the DNA Damage Response and Biomineralization.
K Mueller
– Cell Rep
(2019)
27,
3124
(doi: 10.1016/j.celrep.2019.05.038)
Different soluble aggregates of Aβ42 can give rise to cellular toxicity through different mechanisms.
S De, DC Wirthensohn, P Flagmeier, C Hughes, FA Aprile, FS Ruggeri, DR Whiten, D Emin, Z Xia, JA Varela, P Sormanni, F Kundel, TPJ Knowles, CM Dobson, C Bryant, M Vendruscolo, D Klenerman
– Nature Communications
(2019)
10,
1541
(doi: 10.1038/s41467-019-09477-3)
Spectrally-Resolved Photodynamics Of Individual Emitters In Large-Area Monolayers Of Hexagonal-Boron Nitride.
HL Stern, R Wang, Y Fan, R Mizuta, JC Stewart, L-M Needham, TD Roberts, R Wai, NS Ginsberg, D Klenerman, S Hofmann, SF Lee
– ACS nano
(2019)
13,
4538
(doi: 10.1021/acsnano.9b00274)
Spectrally-Resolved Photodynamics of Individual Emitters in Large-Area Monolayers of Hexagonal-Boron Nitride
HL Stern, R Wang, Y Fan, R Mizuta, JC Stewart, L-M Needham, TD Roberts, R Wai, NS Ginsberg, D Klenerman, S Hofmann, SF Lee
(2019)
(doi: 10.48550/arxiv.1901.02793)
Mapping Surface Hydrophobicity of α‑Synuclein Oligomers at the Nanoscale
J-E Lee, JC Sang, M Rodrigues, AR Carr, MH Horrocks, S De, MN Bongiovanni, P Flagmeier, CM Dobson, DJ Wales, SF Lee, D Klenerman
– Nano Letters
(2018)
18,
7494
(doi: 10.1021/acs.nanolett.8b02916)
Machine Learning for Analysis of Time-Resolved Luminescence Data
N Dordević, JS Beckwith, M Yarema, O Yarema, A Rosspeintner, N Yazdani, J Leuthold, E Vauthey, V Wood
– ACS Photonics
(2018)
5,
4888
(doi: 10.1021/acsphotonics.8b01047)

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