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  • Currently displaying 101 - 120 of 229 publications
Weighing one protein with light.
SF Lee, D Klenerman
– Science
(2018)
360,
378
(doi: 10.1126/science.aat5851)
Combining fluorescence imaging with Hi-C to study 3D genome architecture of the same single cell.
D Lando, S Basu, TJ Stevens, A Riddell, KJ Wohlfahrt, Y Cao, W Boucher, M Leeb, LP Atkinson, SF Lee, B Hendrich, D Klenerman, ED Laue
– Nature protocols
(2018)
13,
1034
(doi: 10.1038/nprot.2018.017)
FUS Phase Separation Is Modulated by a Molecular Chaperone and Methylation of Arginine Cation-π Interactions.
S Qamar, G Wang, SJ Randle, FS Ruggeri, JA Varela, JQ Lin, EC Phillips, A Miyashita, D Williams, F Ströhl, W Meadows, R Ferry, VJ Dardov, GG Tartaglia, LA Farrer, GS Kaminski Schierle, CF Kaminski, CE Holt, PE Fraser, G Schmitt-Ulms, D Klenerman, T Knowles, M Vendruscolo, P St George-Hyslop
– Cell
(2018)
173,
720
(doi: 10.1016/j.cell.2018.03.056)
Comparative analysis of nanobody sequence and structure data
LS Mitchell, LJ Colwell
– Proteins
(2018)
86,
697
(doi: 10.1002/prot.25497)
Elucidation of Excitation Energy Dependent Correlated Triplet Pair Formation Pathways in an Endothermic Singlet Fission System.
A Thampi, H Stern, A Cheminal, J Petty II, J Anthony, A Rao
– Journal of the American Chemical Society
(2018)
140,
4613
(doi: 10.1021/jacs.7b06274)
Correction to 'Bifunctional fluorescent probes for detection of amyloid aggregates and reactive oxygen species'.
L-M Needham, J Weber, JWB Fyfe, OM Kabia, DT Do, E Klimont, Y Zhang, M Rodrigues, CM Dobson, S Gandhi, SE Bohndiek, TN Snaddon, SF Lee
– R Soc Open Sci
(2018)
5,
180308
(doi: 10.1098/rsos.180308)
The small heat shock protein Hsp27 binds -synuclein fibrils, preventing elongation and cytotoxicity
D Cox, DR Whiten, JWP Brown, MH Horrocks, R San Gil, CM Dobson, D Klenerman, AM van Oijen, H Ecroyd
– J Biol Chem
(2018)
293,
4486
(doi: 10.1074/jbc.m117.813865)
Optical Structural Analysis of Individual α‐Synuclein Oligomers
JA Varela, M Rodrigues, S De, P Flagmeier, S Gandhi, CM Dobson, D Klenerman, SF Lee
– Angewandte Chemie
(2018)
130,
4980
(doi: 10.1002/ange.201710779)
Hsp70 Inhibits the Nucleation and Elongation of Tau and Sequesters Tau Aggregates with High Affinity
F Kundel, S De, P Flagmeier, MH Horrocks, M Kjaergaard, SL Shammas, SE Jackson, CM Dobson, D Klenerman
– ACS Chemical Biology
(2018)
13,
636
(doi: 10.1021/acschembio.7b01039)
Shedding light on aberrant interactions - a review of modern tools for studying protein aggregates.
F Kundel, L Tosatto, DR Whiten, DC Wirthensohn, MH Horrocks, D Klenerman
– FEBS Journal
(2018)
285,
3604
(doi: 10.1111/febs.14409)
Capturing resting T cells: the perils of PLL.
AM Santos, A Ponjavic, M Fritzsche, RA Fernandes, JB de la Serna, MJ Wilcock, F Schneider, I Urbančič, J McColl, C Anzilotti, KA Ganzinger, M Aßmann, D Depoil, RJ Cornall, ML Dustin, D Klenerman, SJ Davis, C Eggeling, SF Lee
– Nature immunology
(2018)
19,
203
(doi: 10.1038/s41590-018-0048-8)
Maximizing the field of view and accuracy in 3D Single Molecule Localization Microscopy
SA Rehman, AR Carr, MO Lenz, SF Lee, K O'Holleran
– Opt Express
(2018)
26,
4631
(doi: 10.1364/OE.26.004631)
Detecting RNA base methylations in single cells by in situ hybridization
RT Ranasinghe, MR Challand, KA Ganzinger, BW Lewis, C Softley, WH Schmied, MH Horrocks, N Shivji, JW Chin, J Spencer, D Klenerman
– Nature Communications
(2018)
9,
655
(doi: 10.1038/s41467-017-02714-7)
CLIC4 is regulated by RhoA-mDia2 signaling through Profilin-1 binding to modulate filopodium length
E Argenzio, KM Kedziora, L Nahidiazar, T Isogai, A Perrakis, K Jalink, WH Moolenaar, M Innocenti
(2018)
(doi: 10.1101/259259)
Bifunctional fluorescent probes for detection of amyloid aggregates and reactive oxygen species.
L-M Needham, J Weber, JWB Fyfe, OM Kabia, DT Do, E Klimont, Y Zhang, M Rodrigues, CM Dobson, S Ghandi, SE Bohndiek, TN Snaddon, SF Lee
– Royal Society open science
(2018)
5,
171399
(doi: 10.1098/rsos.171399)
Optical Structural Analysis of Individual α‐Synuclein Oligomers
JA Varela, M Rodrigues, S De, P Flagmeier, S Gandhi, CM Dobson, D Klenerman, SF Lee
– Angewandte Chemie (International ed. in English)
(2018)
57,
4886
(doi: 10.1002/anie.201710779)
Energy transfer and charge separation dynamics in photoexcited pyrene-bodipy molecular dyads.
M Fakis, JS Beckwith, K Seintis, E Martinou, C Nançoz, N Karakostas, I Petsalakis, G Pistolis, E Vauthey
– Physical chemistry chemical physics : PCCP
(2018)
20,
837
(doi: 10.1039/c7cp06914f)
Detecting order and lateral pressure at biomimetic interfaces using a mechanosensitive second-harmonic-generation probe.
G Licari, JS Beckwith, S Soleimanpour, S Matile, E Vauthey
– Phys Chem Chem Phys
(2018)
20,
9328
(doi: 10.1039/c8cp00773j)
Influence of the hydrogen-bond interactions on the excited-state dynamics of a push-pull azobenzene dye: the case of Methyl Orange.
C Nançoz, G Licari, JS Beckwith, M Soederberg, B Dereka, A Rosspeintner, O Yushchenko, R Letrun, S Richert, B Lang, E Vauthey
– Phys Chem Chem Phys
(2018)
20,
7254
(doi: 10.1039/c7cp08390d)
Single-molecule imaging of Wnt3A protein diffusion on living cell membranes
SF Lee, ND Evans, A Lippert, A Janeczek, A Fürstenberg, A Ponjavic, WE Moerner, R Nusse, J Helms
– Biophys J
(2017)
113,
2762
(doi: 10.1016/j.bpj.2017.08.060)

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