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  • Currently displaying 101 - 120 of 202 publications
Nanobodies raised against monomeric α-synuclein inhibit fibril formation and destabilize toxic oligomeric species
D Klenerman, M Iljina, L Hong, MH Horrocks, MH Ludtmann, ML Choi, CD Hughes, FS Ruggeri, T Guilliams, AK Buell, J-E Lee, S Gandhi, SF Lee, CE Bryant, M Vendruscolo, TPJ Knowles, CM Dobson, E De Genst, D Klenerman
– BMC Biol
(2017)
15,
57
(doi: 10.1186/s12915-017-0390-6)
Ultrasensitive Measurement of Ca(2+) Influx into Lipid Vesicles Induced by Protein Aggregates.
P Flagmeier, S De, DC Wirthensohn, SF Lee, C Vincke, S Muyldermans, TPJ Knowles, S Gandhi, CM Dobson, D Klenerman
– Angewandte Chemie (International ed. in English)
(2017)
56,
7750
(doi: 10.1002/anie.201700966)
Ultrasensitive Measurement of Ca2+ Influx into Lipid Vesicles Induced by Protein Aggregates
P Flagmeier, S De, DC Wirthensohn, SF Lee, C Vincke, S Muyldermans, TPJ Knowles, S Gandhi, CM Dobson, D Klenerman
– Angewandte Chemie
(2017)
129,
7858
(doi: 10.1002/ange.201700966)
Three-Dimensional Super-Resolution in Eukaryotic Cells Using the Double-Helix Point Spread Function.
AR Carr, A Ponjavic, S Basu, J McColl, AM Santos, S Davis, ED Laue, D Klenerman, SF Lee
– Biophysical journal
(2017)
112,
1444
(doi: 10.1016/j.bpj.2017.02.023)
PEGylated Liposomes Associate With Wnt3A Protein and Expand Putative Stem Cells in Human Bone Marrow Populations
AA Janeczek, E Scarpa, MH Horrocks, RS Tare, CA Rowland, D Jenner, TA Newman, RO Oreffo, SF Lee, ND Evans
– Nanomedicine
(2017)
12,
845
(doi: 10.2217/nnm-2016-0386)
3D structures of individual mammalian genomes studied by single-cell Hi-C.
TJ Stevens, D Lando, S Basu, LP Atkinson, Y Cao, SF Lee, M Leeb, KJ Wohlfahrt, W Boucher, A O’Shaughnessy-Kirwan, J Cramard, AJ Faure, M Ralser, E Blanco, L Morey, M Sanso, MGS Palayret, B Lehner, L Di Croce, A Wutz, B Hendrich, D Klenerman, ED Laue
– Nature
(2017)
544,
59
(doi: 10.1038/nature21429)
Configurations of the Re‐scan Confocal Microscope (RCM) for biomedical applications
GMR DE Luca, E Desclos, RMP Breedijk, L Dolz-Edo, GJ Smits, L Nahidiazar, P Bielefeld, L Picavet, CP Fitzsimons, R Hoebe, EMM Manders
– Journal of Microscopy
(2017)
266,
166
(doi: 10.1111/jmi.12526)
Rate of Asparagine Deamidation in a Monoclonal Antibody Correlating with Hydrogen Exchange Rate at Adjacent Downstream Residues.
JJ Phillips, A Buchanan, J Andrews, M Chodorge, S Sridharan, L Mitchell, N Burmeister, AD Kippen, TJ Vaughan, DR Higazi, D Lowe
– Analytical chemistry
(2017)
89,
2361
(doi: 10.1021/acs.analchem.6b04158)
Coaggregation of κ-Casein and β-Lactoglobulin Produces Morphologically Distinct Amyloid Fibrils
JK Raynes, L Day, P Crepin, MH Horrocks, JA Carver
– Small (Weinheim an der Bergstrasse, Germany)
(2017)
13,
1603591
(doi: 10.1002/smll.201603591)
Size dependent structure and effects of amyloid beta42
D Wirthensohn, F Kundel, S De, C Hughes, MH Horrocks, P Flagmeier, D Klenerman
– EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
(2017)
46,
S242
(link to publication)
DNA PAINTing amyloid aggregates
MH Horrocks, D Whiten, Y Zuo, L Calo, MG Spillantini, S Gandhi, D Klenerman
– EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
(2017)
46,
S236
(link to publication)
Non-perturbative single-molecule imaging of tau aggregates by genetic code expansion
F Kundel, MH Horrocks, Y Ye, D Klenerman
– EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
(2017)
46,
S240
(link to publication)
DNA PAINTing amyloid aggregates
MH Horrocks, D Whiten, Y Zuo, L Calo, MG Spillantini, S Gandhi, D Klenerman
– EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
(2017)
46,
S68
(link to publication)
Limits for Recombination in a Low Energy Loss Organic Heterojunction.
SM Menke, A Sadhanala, M Nikolka, NA Ran, MK Ravva, S Abdel-Azeim, HL Stern, M Wang, H Sirringhaus, T-Q Nguyen, J-L Brédas, GC Bazan, RH Friend
– ACS Nano
(2016)
10,
10736
(doi: 10.1021/acsnano.6b06211)
Multi-dimensional super-resolution imaging enables surface hydrophobicity mapping
MN Bongiovanni, J Godet, MH Horrocks, L Tosatto, AR Carr, DC Wirthensohn, RT Ranasinghe, JV Fritz, CM Dobson, D Klenerman, SF Lee
– Nature Communications
(2016)
7,
13544
(doi: 10.1038/ncomms13544)
A randomized control trial evaluating fluorescent ink $\textit{versus}$ dark ink tattoos for breast radiotherapy
SJ Landeg, AM Kirby, SF Lee, F Bartlett, K Titmarsh, E Donovan, CL Griffin, L Gothard, I Locke, HA McNair
– Br J Radiol
(2016)
89,
20160288
(doi: 10.1259/bjr.20160288)
Single-nanotube tracking reveals the nanoscale organization of the extracellular space in the live brain.
AG Godin, JA Varela, Z Gao, N Danné, JP Dupuis, B Lounis, L Groc, L Cognet
– Nature nanotechnology
(2016)
12,
238
(doi: 10.1038/nnano.2016.248)
Spatial and Structural Metrics for Living Cells Inspired by Statistical Mechanics.
C Åberg, JA Varela, LW Fitzpatrick, KA Dawson
– Sci Rep
(2016)
6,
34457
(doi: 10.1038/srep34457)
Nanoscopic Cellular Imaging: Confinement Broadens Understanding.
SA Lee, A Ponjavic, C Siv, SF Lee, JS Biteen
– ACS Nano
(2016)
10,
8143
(doi: 10.1021/acsnano.6b02863)
A microfluidic platform for trapping, releasing and super-resolution imaging of single cells
Y Zhou, S Basu, KJ Wohlfahrt, SF Lee, D Klenerman, ED Laue, AA Seshia
– Sens Actuators B Chem
(2016)
232,
680
(doi: 10.1016/j.snb.2016.03.131)

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