skip to content
Home

TheLeeLab

Dr Lisa-Maria Needham

Project: Developing new fluorophores for super-resolution and single-molecule fluorescence Imaging.

Publications

ThX – a next-generation probe for the early detection of amyloid aggregates
L-M Needham, J Weber, JA Varela, JWB Fyfe, DT Do, CK Xu, L Tutton, R Cliffe, B Keenlyside, D Klenerman, CM Dobson, CA Hunter, KH Müller, K O'Holleran, SE Bohndiek, TN Snaddon, SF Lee
– Chemical science
(2020)
11,
4578
(doi: 10.1039/c9sc04730a)
Live-cell 3D single-molecule tracking reveals how NuRD modulates enhancer dynamics
S Basu, O Shukron, D Hall, P Parutto, A Ponjavic, D Shah, W Boucher, D Lando, W Zhang, N Reynolds, LH Sober, A Jartseva, R Ragheb, X Ma, J Cramard, R Floyd, G Brown, J Balmer, TA Drury, AR Carr, L-M Needham, A Aubert, G Communie, K Gor, M Steindel, L Morey, E Blanco, T Bartke, L Di Croce, I Berger, C Schaffitzel, SF Lee, TJ Stevens, D Klenerman, BD Hendrich, D Holcman, ED Laue
– BioRxiv
(2020)
2020.04.03.003178
(doi: 10.1101/2020.04.03.003178)
vLUME: 3D Virtual Reality for Single-molecule Localization Microscopy
A Spark, A Kitching, D Esteban-Ferrer, A Handa, A Carr, L-M Needham, A Ponjavic, MDC Santos, J McColl, C Leterrier, S Davis, R Henriques, S Lee
(2020)
2020.01.20.912733
(doi: 10.1101/2020.01.20.912733)
ThX – A next-generation probe for the early detection of amyloid aggregates
L-M Needham, J Weber, JA Varela, JWB Fyfe, DT Do, CK Xu, D Klenerman, CM Dobson, CA Hunter, SE Bohndiek, TN Snaddon, SF Lee
– BIOPHYSICAL JOURNAL
(2019)
121,
19
(doi: 10.1101/713594)
Poly(ADP-Ribose) Links the DNA Damage Response and Biomineralization.
K Mueller
– Cell reports
(2019)
27,
3124
(doi: 10.1016/j.celrep.2019.05.038)
Spectrally-Resolved Photodynamics Of Individual Emitters In Large-Area Monolayers Of Hexagonal-Boron Nitride.
HL Stern, R Wang, Y Fan, R Mizuta, JC Stewart, L-M Needham, TD Roberts, R Wai, NS Ginsberg, D Klenerman, S Hofmann, SF Lee
– ACS Nano
(2019)
13,
4538
(doi: 10.1021/acsnano.9b00274)
Spectrally-Resolved Photodynamics of Individual Emitters in Large-Area Monolayers of Hexagonal-Boron Nitride
HL Stern, R Wang, Y Fan, R Mizuta, JC Stewart, L-M Needham, TD Roberts, R Wai, NS Ginsberg, D Klenerman, S Hofmann, SF Lee
(2019)
(doi: 10.48550/arxiv.1901.02793)
FRET-enhanced photostability allows improved single-molecule tracking of proteins and protein complexes in live mammalian cells
S Basu, L-M Needham, D Lando, EJR Taylor, KJ Wohlfahrt, D Shah, W Boucher, YL Tan, LE Bates, O Tkachenko, J Cramard, BC Lagerholm, C Eggeling, B Hendrich, D Klenerman, SF Lee, ED Laue
– Nat Commun
(2018)
9,
2520
(doi: 10.1038/s41467-018-04486-0)
Correction to 'Bifunctional fluorescent probes for detection of amyloid aggregates and reactive oxygen species'.
L-M Needham, J Weber, JWB Fyfe, OM Kabia, DT Do, E Klimont, Y Zhang, M Rodrigues, CM Dobson, S Gandhi, SE Bohndiek, TN Snaddon, SF Lee
– Royal Society open science
(2018)
5,
180308
(doi: 10.1098/rsos.180308)
Bifunctional fluorescent probes for detection of amyloid aggregates and reactive oxygen species.
L-M Needham, J Weber, JWB Fyfe, OM Kabia, DT Do, E Klimont, Y Zhang, M Rodrigues, CM Dobson, S Ghandi, SE Bohndiek, TN Snaddon, SF Lee
– Royal Society open science
(2018)
5,
171399
(doi: 10.1098/rsos.171399)
  • <
  • 3 of 4
  • >

Visitor

Telephone number

01223 336410 (shared)

Email address

College

Girton College

    Study at Cambridge

    About the University

    Research at Cambridge