Research Background: PhD and initial post-doctoral research on the use of NMR to study biological molecules and their interactions. Subsequent diverse experience in the pharmaceutical industry (GSK) applying solid state and liquid state NMR and MRI to drug polymorphism, drug receptor characterization, and drug action in biological models of disease.
Research Interests
Current interests focus on solid state NMR to characterize biomaterial structure using cell culture methods and isotope labelling, but also including drug product and timber product characterization.
Teaching
Supporting undergraduate and postgraduate research projects.
Publications
NMR Spectroscopy of Native and in Vitro Tissues Implicates PolyADP Ribose in Biomineralization
– Science (New York, N.Y.)
(2014)
344,
742
(doi: 10.1126/science.1248167)
Citrate bridges between mineral platelets in bone.
– Proceedings of the National Academy of Sciences
(2014)
111,
E1354
(doi: 10.1073/pnas.1315080111)
A new glycation product 'norpronyl-lysine,' and direct characterization of cross linking and other glycation adducts: NMR of model compounds and collagen.
– Bioscience reports
(2014)
34,
e00096
(doi: 10.1042/bsr20130135)
A new glycation product 'norpronyl-lysine' and direct characterization of cross linking and other glycation adducts: NMR of model compounds and collagen.
– Bioscience reports
(2014)
34,
83
(doi: 10.1042/BSR20130135)
Novel “3-D spacer” all fibre piezoelectric textiles for energy harvesting applications
– Energy & Environmental Science
(2014)
7,
1670
(doi: 10.1039/c3ee43987a)
Alternative synthetic methodology for amide formation in the post-synthetic modification of Ti-MIL125-NH 2
– CrystEngComm
(2013)
15,
9368
(doi: 10.1039/c3ce41332b)
The curious case of (caffeine)•(benzoic acid): how heteronuclear seeding allowed the formation of an elusive cocrystal
– Chemical Science
(2013)
4,
4417
(doi: 10.1039/c3sc51419f)
Analysis of commercial proanthocyanidins. Part 4: solid state (13)C NMR as a tool for in situ analysis of proanthocyanidin tannins, in heartwood and bark of quebracho and acacia, and related species.
– Phytochemistry
(2013)
94,
243
Citrate occurs widely in healthy and pathological apatitic biomineral: Mineralized articular cartilage, and intimal atherosclerotic plaque and apatitic kidney stones
– Calcif Tissue Int
(2013)
93,
1
(doi: 10.1007/s00223-013-9751-5)
Analysis of commercial proanthocyanidins. Part 4: Solid state 13C NMR as a tool for in situ analysis of proanthocyanidin tannins, in heartwood and bark of quebracho and acacia, and related species
– Phytochemistry
(2013)
94,
243
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