
Research Background: PhD and initial post-doctoral research on the use of NMR to study biological molecules and their interactions. Subsequent diverse experience in the pharmaceutical industry (GSK) applying solid state and liquid state NMR and MRI to drug polymorphism, drug receptor characterization, and drug action in biological models of disease.
Research Interests
Current interests focus on solid state NMR to characterize biomaterial structure using cell culture methods and isotope labelling, but also including drug product and timber product characterization.
Teaching
Supporting undergraduate and postgraduate research projects.
Publications
Solid state NMR of isotope labelled murine fur: a powerful tool to study atomic level keratin structure and treatment effects.
– J Biomol NMR
(2016)
66,
93
(doi: 10.1007/s10858-016-0056-7)
Rationalization of the Color Properties of Fluorescein in the Solid State: A Combined Computational and Experimental Study
– Chemistry – A European Journal
(2016)
22,
10065
(doi: 10.1002/chem.201601340)
Tuning hardness in calcite by incorporation of amino acids.
– Nature Materials
(2016)
15,
903
(doi: 10.1038/nmat4631)
Connecting defects and amorphization in UiO-66 and MIL-140 metal–organic frameworks: a combined experimental and computational study.
– Phys Chem Chem Phys
(2016)
18,
2192
(doi: 10.1039/c5cp06798g)
Connecting defects and amorphization in UiO-66 and MIL-140 metal–organic frameworks: a combined experimental and computational study
– Phys Chem Chem Phys
(2016)
18,
2192
(doi: 10.1039/c5cp06798g)
Nuclear magnetic resonance spectroscopy fingerprinting of tissues allows detailed analysis of glycation reactions
– INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY
(2016)
97,
A7
Preparation of highly and generally enriched mammalian tissues for solid state NMR
– Journal of Biomolecular NMR
(2015)
63,
119
(doi: 10.1007/s10858-015-9977-9)
Hydroxyproline Ring Pucker Causes Frustration of Helix Parameters in the Collagen Triple Helix
– Scientific Reports
(2015)
5,
12556
(doi: 10.1038/srep12556)
Clinical MRI studies of drug efficacy and safety
– eMagRes
(2015)
4,
345
Collagen labelling with an azide-proline chemical reporter in live cells
– Chemical communications (Cambridge, England)
(2015)
51,
5250
(doi: 10.1039/c4cc07974d)
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