Dr David Reid

Research Background: PhD and initial post-doctoral research on the use of NMR to study biological molecules and their interactions. Subsequent diverse experience in the pharmaceutical industry (GSK) applying solid state and liquid state NMR and MRI to drug polymorphism, drug receptor characterization, and drug action in biological models of disease.

Research Interests

Current interests focus on solid state NMR to characterize biomaterial structure using cell culture methods and isotope labelling, but also including drug product and timber product characterization.

Teaching

Supporting undergraduate and postgraduate research projects.

Publications

Mechanical adaptation of brachiopod shells via hydration-induced structural changes.

J Ihli, AS Schenk, S Rosenfeldt, K Wakonig, M Holler, G Falini, L Pasquini, E Delacou, J Buckman, TS Glen, T Kress, EHR Tsai, DG Reid, MJ Duer, M Cusack, F Nudelman

– Nat Commun

(2021)

12,

5383

(doi: 10.1038/s41467-021-25613-4)

Glycation changes molecular organization and charge distribution in type I collagen fibrils.

S Bansode, U Bashtanova, R Li, J Clark, KH Müller, A Puszkarska, I Goldberga, HH Chetwood, DG Reid, LJ Colwell, JN Skepper, CM Shanahan, G Schitter, P Mesquida, MJ Duer

– Scientific Reports

(2020)

10,

3397

(doi: 10.1038/s41598-020-60250-9)

Detection of nucleic acids and other low abundance components in native bone and osteosarcoma extracellular matrix by isotope enrichment and DNP-enhanced NMR.

I Goldberga, R Li, WY Chow, DG Reid, U Bashtanova, R Rajan, A Puszkarska, H Oschkinat, MJ Duer

– RSC advances

(2019)

26686

(doi: 10.1039/c9ra03198g)

Poly(ADP-ribose) links the DNA damage response to biomineralization

K Mueller

– Cell Rep

(2019)

27,

3124

(doi: 10.1016/j.celrep.2019.05.038)

Synthesis and encapsulation of V(IV,V) compounds in silica nanoparticles targeting development of antioxidant and antiradical nanomaterials.

E Halevas, CM Nday, D Eleftheriadou, G Jackson, V Psycharis, CP Raptopoulou, DG Reid, K Ypsilantis, G Litsardakis, A Salifoglou

– Journal of inorganic biochemistry

(2019)

194,

180

(doi: 10.1016/j.jinorgbio.2018.12.005)

Proline provides site-specific flexibility for in vivo collagen.

WY Chow, CJ Forman, D Bihan, AM Puszkarska, R Rajan, DG Reid, DA Slatter, LJ Colwell, DJ Wales, RW Farndale, MJ Duer

– Scientific reports

(2018)

13809

(doi: 10.1038/s41598-018-31937-x)

Solid state NMR - An indispensable tool in organic-inorganic biocomposite characterization; refining the structure of octacalcium phosphate composites with the linear metabolic di-acids succinate and adipate.

Y Li, DG Reid, MJ Duer, JCC Chan

– Solid State Nucl Magn Reson

(2018)

95,

(doi: 10.1016/j.ssnmr.2018.08.004)