Our research interests originate from a desire to understand and exploit biological systems using organic synthesis primarily. Listed below are areas of research that we are exploring; for more detailed information visit the Spring Group web pages.
• Diversity-Oriented Synthesis
• Synthetic Methodology: Medium Ring Synthesis and Natural Product Synthesis
• Quorum Sensing
• New Antibiotic Discovery
• Modulation of Protein-Protein Interactions
• Molecular Therapeutics: Chemistry-Driven Drug Discovery
We collaborate with many chemical companies and academic groups around the world. The scientific education of group members in organic synthesis is given a high priority; however, they are encouraged also to learn and perform new techniques relating to their projects with our industrial and academic collaborators. Every effort is made so that group members achieve their career ambitions, usually jobs in academia or the chemical industries.
We are extremely fortunate, and grateful, that this research is funded by research councils (A*Star, BBSRC, DAAD, EPSRC, ERC, EU, MRC), charities (CRUK, Cambridge Trusts, Frances and Augustus Newman Foundation, Isaac Newton Trust, Wellcome Trust) and industry (AZ, Bayer Schering, GSK, Lilly, Pfizer, Syngenta, UCB).