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Yusuf Hamied Department of Chemistry

 

Dr Damian Padin Santos

Research Associate

Biography

I was born in a small, but charming, town in the northwest of Spain (Cambados, region of Galicia) and I received my BSc (2013) and MSc (2014) in Chemistry from the University of Santiago de Compostela. In 2019, I obtained my PhD in Organic Chemistry from the same university under the supervision of Prof. Carlos Saá and Prof. Jesús A. Varela working on the development of new chemical transformations based on the catalytic generation of ruthenium vinyl carbenes. In 2017, I was awarded with a Barrié Foundation fellowship to  perform a short stay in the group of Prof. Amir H. Hoveyda (Boston College, USA), where I could learn the basics of  copper-catalysed enantioselective conjugate additions. In April 2020, I joined the group of Prof. Ben L. Feringa at the University of Groningen as a Marie Curie COFUND fellow (within the oLife programme). For 3.5 years at Prof. Feringa group, I could explore many aspects related to chirality, including non-linear effects, spontaneous fractionation of enantiomers, self-induced diastereomeric anisochronism, and their application in asymmetric organocatalysis and organometallic catalysis. Since November 2023, I am research associate at Mateo Sanchez lab (mateosanchezlab.com) at the University of Cambridge, where I will develop new biocatalytic transformations.

Publications

Asymmetric Synthesis of Chiral‐at‐P Alkenylphosphonamidates through Nickel‐Catalyzed C−P Coupling of Phosphoramidites and Alkenyl Halides
X-B Chen, D Padín, CN Stindt, BL Feringa
– Angewandte Chemie International Edition
(2023)
62,
e202307450
(doi: 10.1002/anie.202307450)
Asymmetric Synthesis of Chiral‐at‐P Alkenylphosphonamidates through Nickel‐Catalyzed C−P Coupling of Phosphoramidites and Alkenyl Halides
X Chen, D Padín, CN Stindt, BL Feringa
– Angewandte Chemie
(2023)
135,
(doi: 10.1002/ange.202307450)
Turning Enantiomeric Relationships into Diastereomeric Ones: Self-Resolving α‑Ureidophosphonates and Their Organocatalytic Enantioselective Synthesis
V Dašková, D Padín, BL Feringa
– Journal of the American Chemical Society
(2022)
144,
23603
(doi: 10.1021/jacs.2c10911)
Nonplanar Tub-Shaped Benzocyclooctatetraenes via Halogen-Radical Ring Opening of Dihydrobiphenylenes.
J Bello-García, D Padín, JA Varela, C Saá
– Org Lett
(2021)
23,
5539
(doi: 10.1021/acs.orglett.1c01881)
Cp*RuCl-Vinyl Carbenes: Two Faces and the Bifunctional Role in Catalytic Processes
D Padín, JA Varela, C Saá
– Chemistry – A European Journal
(2020)
26,
7470
(doi: 10.1002/chem.202000391)
Recent Advances in Ruthenium-Catalyzed Carbene/Alkyne Metathesis (CAM) Transformations
D Padín, JA Varela, C Saá
– Synlett
(2020)
31,
1147
(doi: 10.1055/s-0039-1690861)
Ruthenium-Catalyzed Tandem Carbene/Alkyne Metathesis/N-H Insertion: Synthesis of Benzofused Six-Membered Azaheterocycles.
D Padín, JA Varela, C Saá
– Organic letters
(2020)
22,
2621
(doi: 10.1021/acs.orglett.0c00596)
Catalytic Enantioselective Conjugate Addition of Stereodefined Di- and Trisubstituted Alkenylaluminum Compounds to Acyclic Enones
KP McGrath, AK Hubbell, Y Zhou, DP Santos, S Torker, F Romiti, AH Hoveyda
– Advanced Synthesis and Catalysis
(2019)
362,
370
(doi: 10.1002/adsc.201901435)
Vinyl Ruthenium Carbenes: Valuable Intermediates in Catalysis
D Padín, JA Varela, C Saá
(2017)
89
(doi: 10.1007/978-981-10-3421-3_7)
Cycloaddition of Catalytic Ruthenium Vinyl Carbenes: A Stereoselective Controlled Access to (Z)- and (E)-Vinyl Epoxypyrrolidines
D Padín, F Cambeiro, M Fananás-Mastral, JA Varela, C Saá
– ACS Catalysis
(2016)
7,
992
(doi: 10.1021/acscatal.6b02929)

Telephone number

01223 767797 (shared)

Email address

dp721@cam.ac.uk

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