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Mass Spectrometry Services

Structural insights into the EthR-DNA interaction using native mass spectrometry.
Daniel Shiu-Hin Chan, Wei-Guang Seetoh, Brendan N McConnell, Dijana Matak-Vinković, Sherine E Thomas, Vitor Mendes, Michal Blaszczyk, Anthony G Coyne, Tom L Blundell, Chris Abell – Chem Commun (Camb) (2017)
Crystal structure of the N-terminal domain of human Timeless and its interaction with Tipin
Sandro Holzer, Gianluca Degliesposti, Mairi L Kilkenny, Sarah L Maslen, Dijana Matak-Vinkovíc, Mark Skehel, Luca Pellegrini – Nucleic Acids Res (2017)
Mining 2:2 Complexes from 1:1 Stoichiometry: Formation of Cucurbit[8]uril–Diarylviologen Quaternary Complexes Favored by Electron-Donating Substituents
Guanglu Wu, Magdalena Olesińska, Yuchao Wu, Dijana Matak-Vinkovic, and Oren A. Scherman – J. Am. Chem. Soc. (2017) 139 (8), 3202–3208
Insight into Protein Conformation and Subcharging by DMSO from Native Ion Mobility Mass Spectrometry
Daniel Shiu-Hin Chan, Dr Dijana Matak-Vinković, Dr Anthony G. Coyne, Prof Chris Abell – Chemistry Select (2016) 1, 5686–5690
Ctf4 Is a Hub in the Eukaryotic Replisome that Links Multiple CIP-Box Proteins to the CMG Helicase
Fabrizio Villa, Aline C. Simon, Maria Angeles Ortiz Bazan, Mairi L. Kilkenny, David Wirthensohn, Mel Wightman, Dijana Matak-Vinkovíc, Luca Pellegrini,∗ and Karim Labib,∗∗ – Molecular Cell (2016) 63(3), 385–396
Structural characterization of CYP144A1 - a cytochrome P450 enzyme expressed from alternative transcripts in Mycobacterium tuberculosis.
Jude Chenge, Madeline E Kavanagh, Max D Driscoll, Kirsty J McLean, Douglas B Young, Teresa Cortes, Dijana Matak-Vinkovic, Colin W Levy, Stephen E J Rigby, David Leys, Chris Abell, Andrew W Munro – Scientific Reports (2016) 6:26628
Mass Spectrometry Reveals Protein Kinase CK2 High-Order Oligomerization via the Circular and Linear Assembly
Wei-Guang Seetoh, Daniel Shiu-Hin Chan, Dijana Matak-Vinkovic, and Chris Abell – ACS Chem. Biol. (2016)
Structure of a Single-Chain Fv Bound to the 17 N-Terminal Residues of Huntingtin Provides Insights into Pathogenic Amyloid Formation and Suppression
Erwin De Genst, Dimitri Y. Chirgadze, Fabrice A.C. Klein, David C. Butler, Dijana Matak-Vinković, Yvon Trottier, James S. Huston, Anne Messer, Christopher M. Dobson – Journal of Molecular Biology (2015) 427, 2166–2178
An artificial CO-releasing metalloprotein built by histidine-selective metallation
Inês S. Albuquerque, Hélia F. Jeremias, Miguel Chaves-Ferreira, Dijana Matak-Vinkovic, Omar Boutureira, Carlos C. Roma and Gonçalo J. L. Bernardes – Chemical Communications (2015) 51, 3993-3996
Spontaneous CO Release from RuII(CO)2–Protein Complexes in Aqueous Solution, Cells, and Mice†
Dr. Miguel Chaves-Ferreira, Inês S. Albuquerque, Dr. Dijana Matak-Vinkovic, Dr. Ana C. Coelho, Dr. Sandra M. Carvalho, Dr. Lígia M. Saraiva, Prof. Carlos C. Romão and Dr. Gonçalo J. L. Bernardes – Angewandte Chemie (2014)
Suppression of the ​FOXM1 transcriptional programme via novel small molecule inhibition
Michael V. Gormally, Thomas S. Dexheimer, Giovanni Marsico, Deborah A. Sanders, Christopher Lowe, Dijana Matak-Vinković, Sam Michael, Ajit Jadhav, Ganesha Rai, David J. Maloney, Anton Simeonov & Shankar Balasubramanian – Nature Communications (2014) 5
eIF2B is a decameric guanine nucleotide exchange factor with a γ2ε2 tetrameric core
Yuliya Gordiyenko, Carla Schmidt, Martin D. Jennings, Dijana Matak-Vinkovic, Graham D. Pavitt, Carol V. Robinson – Nature Communications (2014) 5, 3902
A Ctf4 trimer couples the CMG helicase to DNA polymerase α in the eukaryotic replisome
Aline C. Simon, Jin C. Zhou, Rajika L. Perera, Frederick van Deursen, Cecile Evrin, Marina E. Ivanova, Mairi L. Kilkenny, Ludovic Renault, Svend Kjaer, Dijana Matak-Vinković, Karim Labib, Alessandro Costa, Luca Pellegrini – Nature (2014) 510, 293-297
Binding Interactions between Long Noncoding RNA HOTAIR and PRC2 Proteins
Liang Wu, Pierre Murat, Dijana Matak-Vinkovic, Adele Murrell, Shankar Balasubramanian – Biochemistry (2013) 52, 9519-9527
Multimeric Complexes among Ankyrin-Repeat and SOCS-box Protein 9 (ASB9), ElonginBC, and Cullin 5: Insights into the Structure and Assembly of ECS-type Cullin-RING E3 Ubiquitin Ligases
Jemima C. Thomas, Dijana Matak-Vinkovic, Inge Van Molle, Alessio Ciulli – Biochemistry (2013) 52, 31
Nanoelectrospray Ionization Mass Spectrometric Study of Mycobacterium tuberculosis CYP121–Ligand Interactions
Katie M. Duffell, Sean A. Hudson, Kirsty J. McLean, Andrew W. Munro, Chris Abell, Dijana Matak-Vinkovic – Analytical Chemistry (2013) 85, 5707-5714
Structure of a Blinkin-BUBR1 Complex Reveals an Interaction Crucial for Kinetochore-Mitotic Checkpoint Regulation via an Unanticipated Binding Site
Victor Martin Bolanos-Garcia, Dimitri Y Chirgadze, E Cota, Tiziana Lischetti, Dijana Matak-Vinković, Jakob Nilsson, Carol V Robinson, Pete J Simpson, David R Spring, Tom L Blundell – Cell (2011) 19, 1691-1700
Mass spectrometry of intact V-type ATPases reveals bound lipids and the effects of nucleotide binding
Min Zhou, Daniela Stock, Nelson P Barrera, Ricardo A Bernal, Shoshanna C Isaacson, Dijana Matak-Vinković, Nina Morgner, Takeshi Murata, Argyris Politis, Carol V Robinson – Science (2011) 334, 380-385
Non-homologous end-joining partners in a helical dance: structural studies of XLF-XRCC4 interactions
Qian Wu, Dimitri Y Chirgadze, Dijana Matak Vinkovic, Takashi Ochi, Carol V Robinson, Tom L Blundell – Biochem Soc Trans (2011) 39(5), 1387-92
Opening of the outer membrane protein channel in tripartite efflux pumps is induced by interaction with the membrane fusion partner
Thamarai K Janganan, Li Zhang, Vassiliy N Bavro, Dijana Matak Vinkovic, Nelson P Barrera, Matthew F Burton, Patrick G Steel, Carol V Robinson, Maria Inês Borges-Walmsley, Adrian R Walmsley – Journal of Biological Chemistry (2011) 286, 5484-5493
A multidrug ABC transporter with a taste for salt
Saroj Velamakanni, Calvin H F Lau, Daniel A P Gutmann, Henrietta Venter, Nelson P Barrera, Markus A Seeger, Barbara Woebking, Dijana Matak Vinkovic, Lekshmy Balakrishnan, Yao Yao, Edmond C Y U, Richard A Shilling, Carol V Robinson, Peter Thorn, Hendrik W Van Veen – PloS one (2009) 4, e6137
The Crystal Structure of the N-Terminal Region of BUB1 Provides Insight into the Mechanism of BUB1 Recruitment to Kinetochores
Victor Martin Bolanos-Garcia, Tomomi Kiyomitsu, Sheena D'Arcy, Dimitri Y Chirgadze, J Günter Grossmann, Dijana Matak-Vinkovic, Ashok R Venkitaraman, Mitsuhiro Yanagida, Carol V Robinson, Tom L Blundell – Cell (2009) 17, 105-116
Subunit Architecture of Intact Protein Complexes from Mass Spectrometry and Homology Modeling
Thomas Taverner, Helena Hernández, Michal Sharon, Brandon T Ruotolo, Dijana Matak-Vinković, Damien Devos, Robert B Russell, Carol V Robinson – Accounts of Chemical Research (2008) 41, 617-627