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The LCT is a TOF (Time of Flight) mass analyser with W optics for enhanced resolution. It ionises samples using the electrospray (ESI) technique with samples being introduced via an Agilent 1100 autosampler and pump to allow unattended 24 hour access (“open access”) to accurate mass determinations of small molecules. The system runs using 50% aqueous acetonitrile with 0.25% formic acid as mobile phase and can measure accurate masses from 150Da to 1500Da. Minimal user interaction is required.