Centre for Experimental Biophysical Chemistry

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  • Currently displaying 741 - 760 of 1109 publications
Author(s)
Publication title
Journal Name
Publication year
A mechanistic model of tau amyloid aggregation based on direct observation of oligomers
SL Shammas, GA Garcia, S Kumar, M Kjaergaard, MH Horrocks, N Shivji, E Mandelkow, TPJ Knowles, E Mandelkow, D Klenerman
Nature Communications
(2015)
6
(doi: 10.1038/ncomms8025)
Preventing peptide and protein misbehavior.
P Arosio, G Meisl, M Andreasen, TPJ Knowles
Proceedings of the National Academy of Sciences of the United States of America
(2015)
112
(doi: 10.1073/pnas.1505170112)
Structural characterization of toxic oligomers that are kinetically trapped during alpha-synuclein fibril formation
SW Chen, S Drakulic, E Deas, MM Ouberai, FA Aprile, R Arranz, S Ness, C Roodveldt, T Guilliams, GE De, D Klenerman, NW Wood, TPJ Knowles, C Alfonso, G Rivas, AY Abramov, JM Valpuesta, CM Dobson, N Cremades
Proceedings of the National Academy of Sciences
(2015)
112
(doi: 10.1073/pnas.1421204112.)
Structural characterization of toxic oligomers that are kinetically trapped during α-synuclein fibril formation.
SW Chen, S Drakulic, E Deas, M Ouberai, FA Aprile, R Arranz, S Ness, C Roodveldt, T Guilliams, EJ De-Genst, D Klenerman, NW Wood, TPJ Knowles, C Alfonso, G Rivas, AY Abramov, JM Valpuesta, CM Dobson, N Cremades
Proceedings of the National Academy of Sciences of the United States of America
(2015)
112
(doi: 10.1073/pnas.1421204112)
On-Demand Delivery of Single DNA Molecules Using Nanopipets
AP Ivanov, P Actis, P Jönsson, D Klenerman, Y Korchev, JB Edel
ACS nano
(2015)
9
(doi: 10.1021/acsnano.5b00911)
Lipid peroxidation is essential for α-synuclein-induced cell death
PR Angelova, MH Horrocks, D Klenerman, S Gandhi, AY Abramov, MS Shchepinov
Journal of Neurochemistry
(2015)
133
(doi: 10.1111/jnc.13024)
A molecular chaperone breaks the catalytic cycle that generates toxic Aβ oligomers
SIA Cohen, P Arosio, J Presto, FR Kurudenkandy, H Biverstål, L Dolfe, C Dunning, X Yang, B Frohm, M Vendruscolo, J Johansson, CM Dobson, A Fisahn, TPJ Knowles, S Linse
Nature Structural and Molecular Biology
(2015)
22
(doi: 10.1038/nsmb.2971)
Lipid peroxidation is essential for α-synuclein-induced cell death
PR Angelova, MH Horrocks, D Klenerman, S Gandhi, AY Abramov, MS Shchepinov
Journal of neurochemistry
(2015)
133
(doi: 10.1111/jnc.13024)
The physical basis of protein misfolding disorders
TPJ Knowles, M Vendruscolo, CM Dobson
Physics Today
(2015)
68
(doi: 10.1063/PT.3.2719)
A molecular chaperone breaks the catalytic cycle that generates toxic Aβ oligomers
SIA Cohen, P Arosio, J Presto, FR Kurudenkandy, H Biverstal, L Dolfe, C Dunning, X Yang, B Frohm, M Vendruscolo, J Johansson, CM Dobson, A Fisahn, TPJ Knowles, S Linse
Nature structural & molecular biology
(2015)
22
(doi: 10.1038/nsmb.2971)
Lipid vesicles trigger α-synuclein aggregation by stimulating primary nucleation.
C Galvagnion, AK Buell, G Meisl, TCT Michaels, M Vendruscolo, TPJ Knowles, CM Dobson
Nature chemical biology
(2015)
11
(doi: 10.1038/nchembio.1750)
Protein microgels from amyloid fibril networks.
U Shimanovich, I Efimov, TO Mason, P Flagmeier, AK Buell, A Gedanken, S Linse, KS Åkerfeldt, CM Dobson, DA Weitz, TPJ Knowles
ACS nano
(2015)
9
(doi: 10.1021/nn504869d)
Single-Molecule FRET Reveals Hidden Complexity in a Protein Energy Landscape
M Tsytlonok, SM Ibrahim, PJE Rowling, W Xu, MJ Ruedas-Rama, A Orte, D Klenerman, LS Itzhaki
Structure
(2015)
23
(doi: 10.1016/j.str.2014.10.023)
On the lag phase in amyloid fibril formation
P Arosio, TPJ Knowles, S Linse
Phys Chem Chem Phys
(2015)
17
(doi: 10.1039/c4cp05563b)
Sizing and interactions of proteins under native conditions from microfluidic diffusion measurements: application to molecular chaperones and single-step immunoassay
P Arosio, T Mueller, L Rajah, F Aprile, T Scheidt, J Carrozza, M Wright, M Vendruscolo, C Dobson, T Knowles
PROTEIN SCIENCE
(2015)
24
New insights into the mechanism of amyloid formation by alpha-synuclein
AK Buell, C Galvagnion, CM Dobson, TPJ Knowles
EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
(2015)
44
Virtual-'Light-Sheet' Single-Molecule Localisation Microscopy Enables Quantitative Optical Sectioning for Super-Resolution Imaging
M Palayret, H Armes, S Basu, AT Watson, A Herbert, D Lando, TJ Etheridge, U Endesfelder, M Heilemann, E Laue, AM Carr, D Klenerman, SF Lee
PloS one
(2015)
10
(doi: 10.1371/journal.pone.0125438)
Lipid vesicles trigger α-synuclein aggregation by stimulating primary nucleation
C Galvagnion, AK Buell, G Meisl, TC Michaels, M Vendruscolo, TPJ Knowles, CM Dobson
EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
(2015)
44
Biophysical approaches for the study of interactions between molecular chaperones and protein aggregates.
MA Wright, FA Aprile, P Arosio, M Vendruscolo, CM Dobson, TPJ Knowles
Chemical communications (Cambridge, England)
(2015)
51
(doi: 10.1039/c5cc03689e)
A microfluidic platform for quantitative measurements of effective protein charges and single ion binding in solution
TW Herling, P Arosio, T Müller, S Linse, TPJ Knowles
Physical Chemistry Chemical Physics
(2015)
17
(doi: 10.1039/c5cp00746a)
Yusuf Hamied Department of Chemistry
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