
Scherman Group Manager
Dr Jade A. McCune completeted her MSci Chemistry (First class Honours) from Queen's University, Belfast (Northern Ireland) followed by her PhD in Chemistry from University of Cambridge. Her PhD research studied the monofunctionalisation of Cucurbit[n]uril macrocycles and their applications as well as the novel solvation of macrocyles in Deep Eutectic Solvents.
Following this, Dr McCune was awarded an EPSRC KT Fellowship to collaboation with MedImmune (AstraZeneca). Jade developed methodology for the bioconjugation of functionalised Cucurbit[n]uril macrocycles and application of these macrocyclic conjugates in vivo.
Jade has also pioneered the use of deep eutectic solvents for supramolecular chemistry which has been utilised towards small molecule and materials chemistry including the stablisation of highly reactive species such as organic radicals.
Publications
Single-Molecule Stoichiometry of Supramolecular Complexes.
– J Am Chem Soc
(2024)
146,
12877
(doi: 10.1021/jacs.4c00611)
Associative pyridinium electrolytes for air-tolerant redox flow batteries.
– Nature
(2023)
623,
949
(doi: 10.1038/s41586-023-06664-7)
Discovery of Urinary Metabolite Biomarkers of Psychiatric Disorders Using Two-Sample Mendelian Randomization
(2023)
(doi: 10.1101/2023.09.26.23296078)
Aktivitätssteigerung von Hydrogenase zur photokatalytischen Wasserstofferzeugung an Luft mittels Lösemitteltuning
– Angewandte Chemie
(2023)
135,
(doi: 10.1002/ange.202219176)
Augmenting the Performance of Hydrogenase for Aerobic Photocatalytic Hydrogen Evolution via Solvent Tuning.
– Angew Chem Int Ed Engl
(2023)
62,
e202219176
(doi: 10.1002/anie.202219176)
Tissue-Mimetic Supramolecular Polymer Networks for Bioelectronics.
– Adv Mater
(2022)
35,
e2207634
(doi: 10.1002/adma.202207634)
On-Resin Recognition of Aromatic Oligopeptides and Proteins through Host-Enhanced Heterodimerization
– J Am Chem Soc
(2022)
144,
8474
(doi: 10.1021/jacs.2c02287)
Facile, Energy-Efficient Microscale Fibrillation of Polyacrylamides under Ambient Conditions.
– Adv Mater
(2022)
34,
e2201577
(doi: 10.1002/adma.202201577)
Highly Compressible Glass-like Supramolecular Polymer Networks
– Nat Mater
(2021)
21,
103
(doi: 10.1038/s41563-021-01124-x)
Nanoparticle surfactants for kinetically arrested photoactive assemblies to track light-induced electron transfer
– Nature nanotechnology
(2021)
16,
1121
(doi: 10.1038/s41565-021-00949-6)
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