Scherman Group Manager
Dr Jade A. McCune completeted her MSci Chemistry (First class Honours) from Queen's University, Belfast (Northern Ireland) followed by her PhD in Chemistry from University of Cambridge. Her PhD research studied the monofunctionalisation of Cucurbit[n]uril macrocycles and their applications as well as the novel solvation of macrocyles in Deep Eutectic Solvents.
Following this, Dr McCune was awarded an EPSRC KT Fellowship to collaboation with MedImmune (AstraZeneca). Jade developed methodology for the bioconjugation of functionalised Cucurbit[n]uril macrocycles and application of these macrocyclic conjugates in vivo.
Jade has also pioneered the use of deep eutectic solvents for supramolecular chemistry which has been utilised towards small molecule and materials chemistry including the stablisation of highly reactive species such as organic radicals.Publications
Stimuli Mediated Ultrastable Radical Formation
– Chem
(2020)
6,
1819
(doi: 10.1016/j.chempr.2020.05.005)
Host-Enhanced Phenyl-Perfluorophenyl Polar-π Interactions
– J Am Chem Soc
(2020)
142,
7356
(doi: 10.1021/jacs.0c02275)
Design Principles for Aqueous Interactive Materials: Lessons from Small Molecules and Stimuli-Responsive Systems.
– Advanced materials (Deerfield Beach, Fla.)
(2020)
32,
e1906890
(doi: 10.1002/adma.201906890)
A comparison of choline:urea and choline:oxalic acid deep eutectic solvents at 338 K
– The Journal of chemical physics
(2018)
148,
193823
(doi: 10.1063/1.5010246)
A simple supramolecular assay for drug detection in urine
– Chem Commun (Camb)
(2017)
53,
8842
(doi: 10.1039/c7cc04081d)
Cucurbit[n]urils
(2017)
1.17
DESolution of CD and CB Macrocycles
– Chemistry (Weinheim an der Bergstrasse, Germany)
(2017)
23,
8601
(doi: 10.1002/chem.201701275)
Modulating the oxidation of cucurbit[n]urils
– Org Biomol Chem
(2017)
15,
998
(doi: 10.1039/c6ob02594c)
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