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  • Currently displaying 121 - 140 of 252 publications
Potassium Arylethynyltrifluoroborate as an Unstrained Dienophile for Ultrafast and On Demand Activation of Bioorthogonal IEDDA Reactions
Z Guo, B Oliveira, C Navo, P M. S. D. Cal, F Corzana, G Jiménez-Osés, G Bernardes
(2019)
Quaternization of Vinyl/Alkynyl Pyridine Enables Ultrafast Cysteine‐Selective Protein Modification and Charge Modulation
MJ Matos, CD Navo, T Hakala, X Ferhati, A Guerreiro, D Hartmann, B Bernardim, KL Saar, I Compañón, F Corzana, TPJ Knowles, G Jiménez‐Osés, GJL Bernardes
– Angewandte Chemie
(2019)
131,
6712
Synthesis, Characterization and Biological Evaluation of New Manganese Metal Carbonyl Compounds That Contain Sulfur and Selenium Ligands as a Promising New Class of CORMs
AL Amorim, MM Peterle, A Guerreiro, DF Coimbra, RS Heying, GF Caramori, AL Braga, AJ Bortoluzzi, A Neves, GJL Bernardes, R Peralta
– Dalton Transactions
(2019)
48,
5574
Norbornene Probes for the Detection of Cysteine Sulfenic Acid in Cells.
LJ Alcock, BL Oliveira, MJ Deery, TL Pukala, MV Perkins, GJL Bernardes, JM Chalker
– ACS chemical biology
(2019)
14,
594
Azabicyclic vinyl sulfones for residue-specific dual protein labelling.
E Gil de Montes, E Jiménez-Moreno, BL Oliveira, CD Navo, PMSD Cal, G Jiménez-Osés, I Robina, AJ Moreno-Vargas, GJL Bernardes
– Chemical Science
(2019)
10,
4515
Natural product-drug conjugates for modulation of TRPV1-expressing tumors
C Baker, T Rodrigues, BP de Almeida, NL Barbosa-Morais, GJL Bernardes
– Bioorganic & Medicinal Chemistry
(2019)
27,
2531
A fully human anti-IL-7Rα antibody promotes antitumor activity against T-cell acute lymphoblastic leukemia
P Akkapeddi, R Fragoso, JA Hixon, AS Ramalho, ML Oliveira, T Carvalho, A Gloger, M Matasci, F Corzana, SK Durum, D Neri, GJL Bernardes, JT Barata
– Leukemia
(2019)
33,
2155
A Fluorogenic Probe for Cell Surface Phosphatidylserine Using an Intramolecular Indicator Displacement Sensing Mechanism
VE Zwicker, BL Oliveira, JH Yeo, ST Fraser, GJL Bernardes, EJ New, KA Jolliffe
– Angewandte Chemie
(2019)
131,
3119
Contemporary approaches to site-selective protein modification
EA Hoyt, PMSD Cal, BL Oliveira, GJL Bernardes
– Nature Reviews Chemistry
(2019)
3,
147
Structure-Based Design of Potent Tumor-Associated Antigens: Modulation of Peptide Presentation by Single-Atom O/S or O/Se Substitutions at the Glycosidic Linkage
I Compañón, A Guerreiro, V Mangini, J Castro-López, M Escudero-Casao, A Avenoza, JH Busto, S Castillón, J Jiménez-Barbero, JL Asensio, G Jiménez-Osés, O Boutureira, JM Peregrina, R Hurtado-Guerrero, R Fiammengo, GJL Bernardes, F Corzana
– J Am Chem Soc
(2019)
141,
4063
De novo design of potent and selective mimics of IL-2 and IL-15.
D-A Silva, S Yu, UY Ulge, JB Spangler, KM Jude, C Labão-Almeida, LR Ali, A Quijano-Rubio, M Ruterbusch, I Leung, T Biary, SJ Crowley, E Marcos, CD Walkey, BD Weitzner, F Pardo-Avila, J Castellanos, L Carter, L Stewart, SR Riddell, M Pepper, GJL Bernardes, M Dougan, KC Garcia, D Baker
– Nature
(2019)
565,
186
Efficient and irreversible antibody–cysteine bioconjugation using carbonylacrylic reagents
B Bernardim, MJ Matos, X Ferhati, I Compañón, A Guerreiro, P Akkapeddi, ACB Burtoloso, G Jiménez-Osés, F Corzana, GJL Bernardes
– Nat Protoc
(2019)
14,
86
Lysine Bioconjugation on Native Albumin with a Sulfonyl Acrylate Reagent.
MJ Matos, G Jiménez-Osés, GJL Bernardes
– Methods Mol Biol
(2019)
2033,
25
One-pot stapling of interchain disulfides of antibodies using an isobutylene motif.
S Sun, P Akkapeddi, MC Marques, N Martínez-Sáez, VM Torres, C Cordeiro, O Boutureira, GJL Bernardes
– Organic & Biomolecular Chemistry
(2018)
17,
2005
Protein engineering through chemical, genetic and computational manipulation
I Hamachi, GJL Bernardes
– Chemical Society Reviews
(2018)
47,
8977
Bioorthogonal Decaging Reactions for Targeted Drug Activation.
S Davies, BJ Stenton, GJL Bernardes
– Chimia
(2018)
72,
771
Radical-Mediated Thiol-Ene Strategy: Photoactivation of Thiol-Containing Drugs in Cancer Cells
GJ Lopes Bernardes
– Angewandte Chemie (International ed. in English)
(2018)
130,
16058
Modular Pore-Forming Immunotoxins with Caged Cytotoxicity Tailored by Directed Evolution.
NL Mutter, M Soskine, G Huang, IS Albuquerque, GJL Bernardes, G Maglia
– ACS Chem Biol
(2018)
13,
3153
Cisplatin-Triggered Bioorthogonal Decaging of Amide Bonds for Targeted-Drug Activation in vivo
B Stenton, B Oliveira, J Conde, M Negrão, M Godinho Ferreira, R Fior, G Bernardes
(2018)
Posttranslational Chemical Mutagenesis: To Reveal the Role of Noncatalytic Cysteine Residues in Pathogenic Bacterial Phosphatases
JB Bertoldo, H Terenzi, S Hüttelmaier, GJL Bernardes
– Biochemistry
(2018)
57,
6144