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  • Currently displaying 101 - 120 of 252 publications
The antidiabetic drug lobeglitazone has the potential to inhibit PTP1B activity.
RF Rocha, T Rodrigues, ACO Menegatti, GJL Bernardes, H Terenzi
– Bioorg Chem
(2020)
100,
103927
(doi: 10.1016/j.bioorg.2020.103927)
A Microfluidic Co-Flow Route for Human Serum Albumin-drugnanoparticle assembly
TA Hakala, S Davies, Z Toprakcioglu, B Bernardim, GJL Bernardes, TPJ Knowles
– Chemistry – A European Journal
(2020)
26,
5965
(doi: 10.1002/chem.202001146)
Synthesis, conformational analysis and: In vivo assays of an anti-cancer vaccine that features an unnatural antigen based on an sp2-iminosugar fragment
IA Bermejo, CD Navo, J Castro-López, A Guerreiro, E Jiménez-Moreno, EM Sánchez Fernández, F García-Martín, H Hinou, S-I Nishimura, JM García Fernández, CO Mellet, A Avenoza, JH Busto, GJL Bernardes, R Hurtado-Guerrero, JM Peregrina, F Corzana
– Chem Sci
(2020)
11,
3996
(doi: 10.1039/c9sc06334j)
Stable Pyrrole‐Linked Bioconjugates through Tetrazine‐Triggered Azanorbornadiene Fragmentation
E Gil de Montes, A Istrate, CD Navo, E Jiménez‐Moreno, EA Hoyt, F Corzana, I Robina, G Jiménez‐Osés, AJ Moreno‐Vargas, GJL Bernardes
– Angewandte Chemie
(2020)
132,
6255
(doi: 10.1002/ange.201914529)
Multi-scale microporous silica microcapsules from gas-in water-in oil emulsions
Z Toprakcioglu, TA Hakala, A Levin, CFW Becker, GGL Bernandes, TPJ Knowles
– Soft Matter
(2020)
16,
3082
(doi: 10.1039/c9sm02274k)
Stable Pyrrole‐Linked Bioconjugates through Tetrazine‐Triggered Azanorbornadiene Fragmentation
E Gil de Montes, A Istrate, CD Navo, E Jiménez-Moreno, EA Hoyt, F Corzana, I Robina, G Jiménez-Osés, AJ Moreno-Vargas, GJL Bernardes
– Angewandte Chemie - International Edition
(2020)
59,
6196
(doi: 10.1002/anie.201914529)
Proteome-Wide Survey of Cysteine Oxidation by Using a Norbornene Probe.
LJ Alcock, M Langini, K Stühler, M Remke, MV Perkins, GJL Bernardes, JM Chalker
– ChemBioChem
(2019)
21,
1329
(doi: 10.1002/cbic.201900729)
Machine learning for target discovery in drug development
T Rodrigues, GJL Bernardes
– Current Opinion in Chemical Biology
(2019)
56,
16
(doi: 10.1016/j.cbpa.2019.10.003)
A Sweet Galactose Transfer – Metabolic Oligosaccharide Engineering as a Tool to Study Glycans in Plasmodium Infection
A Kitowski, G Bernardes
(2019)
(doi: 10.26434/chemrxiv.10119302.v1)
Enhancement of the Anti-Aggregation Activity of a Molecular Chaperone Using a Rationally Designed Post-Translational Modification.
PR Lindstedt, FA Aprile, MJ Matos, M Perni, JB Bertoldo, B Bernardim, Q Peter, G Jiménez-Osés, TPJ Knowles, CM Dobson, F Corzana, M Vendruscolo, GJL Bernardes
– ACS Central Science
(2019)
5,
1417
(doi: 10.1021/acscentsci.9b00467)
Evaluation of linker length effects on a BET bromodomain probe
R Traquete, E Henderson, S Picaud, PMSD Cal, F Sieglitz, T Rodrigues, R Oliveira, P Filippakopoulos, GJL Bernardes
– Chemical communications (Cambridge, England)
(2019)
55,
10128
(doi: 10.1039/c9cc05054j)
Ethynylbenziodoxolone Reactivity in Cysteine Bioconjugation
SR Adusumalli, GJL Bernardes
– Chem
(2019)
5,
1932
(doi: 10.1016/j.chempr.2019.07.014)
Overexpression of osmosensitive Ca2+-activated channel TMEM63B promotes migration in HEK293T cells
M Marques, I Albuquerque, S Vaz, G Bernardes
– Biochemistry
(2019)
626010
(doi: 10.1101/626010)
Overexpression of Osmosensitive Ca2+-Permeable Channel TMEM63B Promotes Migration in HEK293T Cells.
MC Marques, IS Albuquerque, SH Vaz, GJL Bernardes
– Biochemistry
(2019)
58,
2861
(doi: 10.1021/acs.biochem.9b00224)
Tetrazine‐Triggered Release of Carboxylic‐Acid‐Containing Molecules for Activation of an Anti‐inflammatory Drug
S Davies, L Qiao, BL Oliveira, CD Navo, G Jiménez-Osés, GJL Bernardes
– Chembiochem : a European journal of chemical biology
(2019)
20,
1541
(doi: 10.1002/cbic.201900098)
Triaminopyrimidine derivatives as transmembrane HCl transporters.
P Motloch, A Guerreiro, CQ Azeredo, GJL Bernardes, CA Hunter, I Kocsis
– Organic & Biomolecular Chemistry
(2019)
17,
5633
(doi: 10.1039/c9ob00725c)
Development of a self-immolative linker for tetrazine-triggered release of alcohols in cells
S Davies, B Oliveira, GJL Bernardes
– Organic & Biomolecular Chemistry
(2019)
17,
5725
(doi: 10.1039/c9ob01167f)
Quaternization of Vinyl/Alkynyl Pyridine Enables Ultrafast Cysteine‐Selective Protein Modification and Charge Modulation
MJ Matos, CD Navo, T Hakala, X Ferhati, A Guerreiro, D Hartmann, B Bernardim, KL Saar, I Compañón, F Corzana, TPJ Knowles, G Jiménez-Osés, GJL Bernardes
– Angewandte Chemie International Edition
(2019)
58,
6640
(doi: 10.1002/anie.201901405)
Dissecting celastrol with machine learning to unveil dark pharmacology
T Rodrigues, BP de Almeida, NL Barbosa-Morais, GJL Bernardes
– Chem Commun (Camb)
(2019)
55,
6369
(doi: 10.1039/c9cc03116b)
Computational advances in combating colloidal aggregation in drug discovery
D Reker, GJL Bernardes, T Rodrigues
– Nature chemistry
(2019)
11,
402
(doi: 10.1038/s41557-019-0234-9)

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