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Data-Driven Drug Discovery and Molecular Informatics

Dr Dezsö Modos

Publications

Community assessment to advance computational prediction of cancer drug combinations in a pharmacogenomic screen
MP Menden, D Wang, MJ Mason, B Szalai, KC Bulusu, Y Guan, T Yu, J Kang, M Jeon, R Wolfinger, T Nguyen, M Zaslavskiy, AstraZeneca-Sanger Drug Combination DREAM Consortium, IS Jang, Z Ghazoui, ME Ahsen, R Vogel, EC Neto, T Norman, EKY Tang, MJ Garnett, GYD Veroli, S Fawell, G Stolovitzky, J Guinney, JR Dry, J Saez-Rodriguez
– Nat Commun
(2019)
10,
2674
(doi: 10.1038/s41467-019-09799-2)
Systems genomics of ulcerative colitis: combining GWAS and signalling networks for patient stratification and individualised drug targeting in ulcerative colitis
J Brooks, D Modos, P Sudhakar, D Fazekas, A Zoufir, A Watson, M Tremelling, B Verstockt, S Vermeire, A Bender, S Carding, T Korcsmaros
– Journal of Crohn's and Colitis
(2019)
13,
S6
(doi: 10.1093/ecco-jcc/jjy222.009)
Signalling and transcriptional network propagation uncovers novel ulcerative colitis pathogenetic pathways from single-nucleotide polymorphisms
D Modos, J Brooks, P Sudhakar, B Verstockt, B Alexander-Dann, A Zoufir, D Fazekas, S Vermeire, T Korcsmaros, A Bender
– Journal of Crohn's and Colitis
(2019)
13,
s091
(doi: 10.1093/ecco-jcc/jjy222.135)
Developments in toxicogenomics: Understanding and predicting compound-induced toxicity from gene expression data
B Alexander-Dann, LL Pruteanu, E Oerton, N Sharma, I Berindan-Neagoe, D Módos, A Bender
– RSC Molecular Omics
(2018)
14,
218
(doi: 10.1039/c8mo00042e)
Neighbours of cancer-related proteins have key influence on pathogenesis and could increase the drug target space for anticancer therapies
D Módos, KC Bulusu, D Fazekas, J Kubisch, J Brooks, I Marczell, PM Szabó, T Vellai, P Csermely, K Lenti, A Bender, T Korcsmáros
– npj Systems Biology and Applications
(2017)
3,
2
(doi: 10.1038/s41540-017-0003-6)
Identification of critical paralog groups with indispensable roles in the regulation of signaling flow
D Modos, J Brooks, D Fazekas, E Ari, T Vellai, P Csermely, T Korcsmaros, K Lenti
– Sci Rep
(2016)
6,
38588
(doi: 10.1038/srep38588)
SignaFish: A Zebrafish-Specific Signaling Pathway Resource
K Csályi, D Fazekas, T Kadlecsik, D Türei, L Gul, B Horváth, D Módos, A Demeter, N Pápai, K Lenti, P Csermely, T Vellai, T Korcsmáros, M Varga
– Zebrafish
(2016)
13,
541
(doi: 10.1089/zeb.2016.1277)
CompArAtiVe stUdy oF hyGiene hABits in three diFFerent GroUps in hUnGAry
C Földvári-Nagy, KC Földvári-Nagy, D Módos, K Lenti
– New Medicine
(2016)
20,
141
(doi: 10.5604/14270994.1228169)
Targets of drugs are generally, and targets of drugs having side effects are specifically good spreaders of human interactome perturbations.
ÁR Perez-Lopez, KZ Szalay, D Türei, D Módos, K Lenti, T Korcsmáros, P Csermely
– Sci Rep
(2015)
5,
10182
(doi: 10.1038/srep10182)
Autophagy Regulatory Network — A systems-level bioinformatics resource for studying the mechanism and regulation of autophagy
D Türei, L Földvári-Nagy, D Fazekas, D Módos, J Kubisch, T Kadlecsik, A Demeter, K Lenti, P Csermely, T Vellai, T Korcsmáros
– Autophagy
(2015)
11,
155
(doi: 10.4161/15548627.2014.994346)
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Telephone number

01223 763078 (shared)

Study at Cambridge

About the University

Research at Cambridge