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  • Currently displaying 461 - 480 of 1102 publications
Soluble aggregates present in cerebrospinal fluid change in size and mechanism of toxicity during Alzheimer's disease progression
S De, DR Whiten, FS Ruggeri, C Hughes, M Rodrigues, DI Sideris, CG Taylor, FA Aprile, S Muyldermans, TPJ Knowles, M Vendruscolo, C Bryant, K Blennow, I Skoog, S Kern, H Zetterberg, D Klenerman
– Acta neuropathologica communications
(2019)
7,
120
(doi: 10.1186/s40478-019-0777-4)
ThX: a next generation probe for the early detection of amyloid aggregates
L-M Needham, J Weber, JA Varela, JWB Fyfe, DT Do, CK Xu, D Klenerman, CM Dobson, CA Hunter, SE Bohndiek, TN Snaddon, SF Lee
– BIOPHYSICAL JOURNAL
(2019)
121,
713594
(doi: 10.1101/713594)
Clathrin-Inspired Coating and Stabilization of Liposomes by DNA Self-Assembly
KN Baumann, L Piantanida, J García-Nafría, D Sobota, K Voïtchovsky, TPJ Knowles, S HERNANDEZ AINSA
(2019)
(doi: 10.26434/chemrxiv.8859017)
Clathrin-Inspired Coating and Stabilization of Liposomes by DNA Self-Assembly
K Baumann, L Piantanida, J García-Nafría, D Sobota, K Voïtchovsky, T Knowles, SILVIA HERNANDEZ AINSA
(2019)
(doi: 10.26434/chemrxiv.8859017.v1)
Rapid two-dimensional characterisation of proteins in solution.
KL Saar, Q Peter, T Müller, PK Challa, TW Herling, TPJ Knowles
– Microsystems & Nanoengineering
(2019)
5,
33
(doi: 10.1038/s41378-019-0072-3)
Universality of filamentous aggregation phenomena
TCT Michaels, AJ Dear, TPJ Knowles
– Physical Review E
(2019)
99,
062415
(doi: 10.1103/physreve.99.062415)
A cell-topography based mechanism for ligand discrimination by the T-cell receptor
RA Fernandes, KA Ganzinger, JC Tzou, P Jönsson, SF Lee, M Palayret, AM Santos, AR Carr, A Ponjavic, VT Chang, C Macleod, BC Lagerholm, AE Lindsay, O Dushek, A Tilevik, SJ Davis, D Klenerman
– Proceedings of the National Academy of Sciences of the United States of America
(2019)
116,
14002
(doi: 10.1073/pnas.1817255116)
Analysis of αB-crystallin polydispersity in solution through native microfluidic electrophoresis.
MA Wright, FS Ruggeri, KL Saar, PK Challa, JLP Benesch, TPJ Knowles
– Analyst
(2019)
144,
4413
(doi: 10.1039/c9an00382g)
Programmable On-Chip Artificial Cell Producing Post-Translationally Modified Ubiquitinated Protein.
S Zilberzwige-Tal, A Levin, Z Toprakcioglu, TPJ Knowles, E Gazit, J Elbaz
– Small
(2019)
15,
e1901780
(doi: 10.1002/smll.201901780)
Poly(ADP-ribose) links the DNA damage response to biomineralization
K Mueller
– Cell reports
(2019)
27,
3124
(doi: 10.1016/j.celrep.2019.05.038)
A generalin vitroassay to study enzymatic activities of the ubiquitin system
Y Zuo, BK Chong, K Jiang, D Finley, D Klenerman, Y Ye
(2019)
660894
(doi: 10.1101/660894)
Quaternization of Vinyl/Alkynyl Pyridine Enables Ultrafast Cysteine-Selective Protein Modification and Charge Modulation
MJ Matos, CD Navo, T Hakala, X Ferhati, A Guerreiro, D Hartmann, B Bernardim, KL Saar, I Compañón, F Corzana, TPJ Knowles, G Jiménez-Osés, GJL Bernardes
– Angewandte Chemie - International Edition
(2019)
58,
6640
(doi: 10.1002/anie.201901405)
Secondary nucleation and elongation occur at different sites on Alzheimer's amyloid-β aggregates
T Scheidt, U Łapińska, JR Kumita, DR Whiten, D Klenerman, MR Wilson, SIA Cohen, S Linse, M Vendruscolo, CM Dobson, TPJ Knowles, P Arosio
– Sci Adv
(2019)
5,
eaau3112
(doi: 10.1126/sciadv.aau3112)
Sequence‐Optimized Peptide Nanofibers as Growth Stimulators for Regeneration of Peripheral Neurons
C Schilling, T Mack, S Lickfett, S Sieste, FS Ruggeri, T Sneideris, A Dutta, T Bereau, R Naraghi, D Sinske, TPJ Knowles, CV Synatschke, T Weil, B Knöll
– Advanced Functional Materials
(2019)
29,
1809112
(doi: 10.1002/adfm.201809112)
3D microfluidics spray nozzle for sample processing and materials deposition
T Kartanas, R Rodrigues, T Müller, T Herling, T Knowles, J Charmet
– 3RD BIOMEDICAL ENGINEERING'S RECENT PROGRESS IN BIOMATERIALS, DRUGS DEVELOPMENT, AND MEDICAL DEVICES
(2019)
2096,
020007
(doi: 10.1063/1.5096675)
Quaternization of Vinyl/Alkynyl Pyridine Enables Ultrafast Cysteine‐Selective Protein Modification and Charge Modulation
MJ Matos, CD Navo, T Hakala, X Ferhati, A Guerreiro, D Hartmann, B Bernardim, KL Saar, I Compañón, F Corzana, TPJ Knowles, G Jiménez‐Osés, GJL Bernardes
– Angewandte Chemie
(2019)
131,
6712
(doi: 10.1002/ange.201901405)
ADSoluble aggregates present in cerebrospinal fluid change in size and mechanism of toxicity during Alzheimer’s disease progression
S De, D Whiten, F Ruggeri, C Hughes, M Rodrigues, D Sideris, C Taylor, F Aprile, S Muyldermans, T Knowles, M Vendruscolo, C Bryant, K Blennow, I Skoog, S Kern, H Zetterberg, D Klenerman
(2019)
600346
(doi: 10.1101/600346)
Different soluble aggregates of Aβ42 can give rise to cellular toxicity through different mechanisms.
S De, DC Wirthensohn, P Flagmeier, C Hughes, FA Aprile, FS Ruggeri, DR Whiten, D Emin, Z Xia, JA Varela, P Sormanni, F Kundel, TPJ Knowles, CM Dobson, C Bryant, M Vendruscolo, D Klenerman
– Nat Commun
(2019)
10,
1541
(doi: 10.1038/s41467-019-09477-3)
Citrullination of HP1 chromodomain affects association with chromatin
M Wiese, AJ Bannister, S Basu, W Boucher, K Wohlfahrt, MA Christophorou, ML Nielsen, D Klenerman, ED Laue, T Kouzarides
– Epigenetics & Chromatin
(2019)
12,
21
(doi: 10.1186/s13072-019-0265-x)
Direct observation of prion protein oligomer formation reveals an aggregation mechanism with multiple conformationally distinct species
JC Sang, J-E Lee, AJ Dear, S De, G Meisl, AM Thackray, R Bujdoso, TPJ Knowles, D Klenerman
– Chem Sci
(2019)
10,
4588
(doi: 10.1039/c8sc05627g)

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