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  • Currently displaying 401 - 420 of 1101 publications
A Microfluidic Co-Flow Route for Human Serum Albumin-Drug–Nanoparticle Assembly
TA Hakala, S Davies, Z Toprakcioglu, B Bernardim, GJL Bernardes, TPJ Knowles
– Chemistry
(2020)
26,
5965
(doi: 10.1002/chem.202001146)
Insoluble tau aggregates induce neuronal death through modification of membrane ion conductance, activation of voltage‐gated calcium channels and NADPH oxidase
N Esteras, F Kundel, GF Amodeo, EV Pavlov, D Klenerman, AY Abramov
– FEBS Journal
(2020)
288,
127
(doi: 10.1111/febs.15340)
Complexity in Lipid Membrane Composition Induces Resilience to Aβ42 Aggregation
M Sanguanini, KN Baumann, S Preet, S Chia, J Habchi, TPJ Knowles, M Vendruscolo
– ACS Chem Neurosci
(2020)
11,
1347
(doi: 10.1021/acschemneuro.0c00101)
Alpha synuclein aggregation drives ferroptosis: an interplay of iron, calcium and lipid peroxidation.
PR Angelova, ML Choi, AV Berezhnov, MH Horrocks, CD Hughes, S De, M Rodrigues, R Yapom, D Little, KS Dolt, T Kunath, MJ Devine, P Gissen, MS Shchepinov, S Sylantyev, EV Pavlov, D Klenerman, AY Abramov, S Gandhi
– Cell Death and Differentiation
(2020)
27,
2781
(doi: 10.1038/s41418-020-0542-z)
A fluorescent molecular imaging probe with selectivity for soluble tau aggregated protein
Y Zhao, O Tietz, W-L Kuan, AK Haji-Dheere, S Thompson, B Vallin, E Ronchi, G Tóth, D Klenerman, FI Aigbirhio
– Chemical Science
(2020)
11,
4773
(doi: 10.1039/c9sc05620c)
Surface electrostatics govern the emulsion stability of biomolecular condensates
T Welsh, G Krainer, J Espinosa, J Joseph, A Sridhar, M Jahnel, W Arter, K Saar, S Alberti, R Collepardo-Guevara, TPJ Knowles
(2020)
2020.04.20.047910
(doi: 10.1101/2020.04.20.047910)
Author Correction: Dynamics of oligomer populations formed during the aggregation of Alzheimer's Aβ42 peptide.
TCT Michaels, A Šarić, S Curk, K Bernfur, P Arosio, G Meisl, AJ Dear, SIA Cohen, CM Dobson, M Vendruscolo, S Linse, TPJ Knowles
– Nature chemistry
(2020)
12,
497
(doi: 10.1038/s41557-020-0468-6)
Mechanism of droplet-formation in a supersonic microfluidic spray device
T Kartanas, Z Toprakcioglu, TA Hakala, A Levin, TW Herling, R Daly, J Charmet, TPJ Knowles
– Applied Physics Letters
(2020)
116,
153702
(doi: 10.1063/1.5145109)
Dynamics of oligomer populations formed during the aggregation of Alzheimer’s Aβ42 peptide
TCT Michaels, A Šarić, S Curk, K Bernfur, P Arosio, G Meisl, AJ Dear, SIA Cohen, CM Dobson, M Vendruscolo, S Linse, TPJ Knowles
– Nature chemistry
(2020)
12,
445
(doi: 10.1038/s41557-020-0452-1)
Microfluidic approaches for the analysis of protein–protein interactions in solution
WE Arter, A Levin, G Krainer, TPJ Knowles
– Biophysical Reviews
(2020)
12,
575
(doi: 10.1007/s12551-020-00679-4)
Live-cell 3D single-molecule tracking reveals how NuRD modulates enhancer dynamics
S Basu, O Shukron, D Hall, P Parutto, A Ponjavic, D Shah, W Boucher, D Lando, W Zhang, N Reynolds, LH Sober, A Jartseva, R Ragheb, X Ma, J Cramard, R Floyd, G Brown, J Balmer, TA Drury, AR Carr, L-M Needham, A Aubert, G Communie, K Gor, M Steindel, L Morey, E Blanco, T Bartke, L Di Croce, I Berger, C Schaffitzel, SF Lee, TJ Stevens, D Klenerman, BD Hendrich, D Holcman, ED Laue
– BioRxiv
(2020)
2020.04.03.003178
(doi: 10.1101/2020.04.03.003178)
Ultrathin Polydopamine Films with Phospholipid Nanodiscs Containing a Glycophorin A Domain
T Marchesi D'Alvise, S Harvey, L Hueske, J Szelwicka, L Veith, TPJ Knowles, D Kubiczek, C Flaig, F Port, KE Gottschalk, F Rosenau, B Graczykowski, G Fytas, FS Ruggeri, K Wunderlich, T Weil
– Advanced Functional Materials
(2020)
30,
2000378
(doi: 10.1002/adfm.202000378)
The Influence of Pathogenic Mutations in α-Synuclein on Biophysical and Structural Characteristics of Amyloid Fibrils
FS Ruggeri, P Flagmeier, JR Kumita, G Meisl, DY Chirgadze, MN Bongiovanni, TPJ Knowles, CM Dobson
– ACS Nano
(2020)
14,
5213
(doi: 10.1021/acsnano.9b09676)
Effects of sedimentation, microgravity, hydrodynamic mixing and air-water interface on α-synuclein amyloid formation
J Zhou, FS Ruggeri, MR Zimmermann, G Meisl, G Longo, SK Sekatskii, TPJ Knowles, G Dietler
– Chem Sci
(2020)
11,
3687
(doi: 10.1039/d0sc00281j)
Multi-scale microporous silica microcapsules from gas-in water-in oil emulsions
Z Toprakcioglu, TA Hakala, A Levin, CFW Becker, GGL Bernandes, TPJ Knowles
– Soft matter
(2020)
16,
3082
(doi: 10.1039/c9sm02274k)
Lipid-Stabilized Double Emulsions Generated in Planar Microfluidic Devices
L Kong, A Levin, Z Toprakcioglu, Y Xu, H Gang, R Ye, B-Z Mu, TPJ Knowles
– Langmuir
(2020)
36,
2349
(doi: 10.1021/acs.langmuir.9b03622)
Autoantibodies against the prion protein in individuals with PRNP mutations.
K Frontzek, M Carta, M Losa, M Epskamp, G Meisl, A Anane, J-P Brandel, U Camenisch, J Castilla, S Haïk, T Knowles, E Lindner, A Lutterotti, EV Minikel, I Roiter, JG Safar, R Sanchez-Valle, D Žáková, S Hornemann, A Aguzzi, THAUTAN-MC Study Group
– Neurology
(2020)
95,
E2028
(doi: 10.1212/WNL.0000000000009183)
The molecular processes underpinning prion-like spreading and seed amplification in protein aggregation.
G Meisl, TP Knowles, D Klenerman
– Curr Opin Neurobiol
(2020)
61,
58
(doi: 10.1016/j.conb.2020.01.010)
Beta amyloid aggregates induce sensitised TLR4 signalling causing long-term potentiation deficit and rat neuronal cell death
C Hughes, ML Choi, J-H Yi, S-C Kim, A Drews, PS George-Hyslop, C Bryant, S Gandhi, K Cho, D Klenerman
– Commun Biol
(2020)
3,
79
(doi: 10.1038/s42003-020-0792-9)
Transthyretin Inhibits Primary and Secondary Nucleations of Amyloid-β Peptide Aggregation and Reduces the Toxicity of Its Oligomers
SA Ghadami, S Chia, FS Ruggeri, G Meisl, F Bemporad, J Habchi, R Cascella, CM Dobson, M Vendruscolo, TPJ Knowles, F Chiti
– Biomacromolecules
(2020)
21,
1112
(doi: 10.1021/acs.biomac.9b01475)

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