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  • Currently displaying 501 - 520 of 1100 publications
Resolving protein mixtures using microfluidic diffusional sizing combined with synchrotron radiation circular dichroism.
C Bortolini, T Kartanas, D Copic, I Condado Morales, Y Zhang, PK Challa, Q Peter, T Jávorfi, R Hussain, M Dong, G Siligardi, TPJ Knowles, J Charmet
– Lab on a Chip
(2018)
19,
50
(doi: 10.1039/c8lc00757h)
Mapping Surface Hydrophobicity of α-Synuclein Oligomers at the Nanoscale
J-E Lee, JC Sang, M Rodrigues, AR Carr, MH Horrocks, S De, MN Bongiovanni, P Flagmeier, CM Dobson, DJ Wales, SF Lee, D Klenerman
– Nano Lett
(2018)
18,
7494
(doi: 10.1021/acs.nanolett.8b02916)
Image-Assisted Microvessel-on-a-Chip Platform for Studying Cancer Cell Transendothelial Migration Dynamics.
C Bertulli, M Gerigk, N Piano, Y Liu, D Zhang, T Müller, TJ Knowles, YYS Huang
– Sci Rep
(2018)
8,
12480
(doi: 10.1038/s41598-018-30776-0)
Mechanobiology of Protein Droplets: Force Arises from Disorder.
TJ Welsh, Y Shen, A Levin, TPJ Knowles
– Cell
(2018)
175,
1457
(doi: 10.1016/j.cell.2018.11.020)
Quantifying Co-Oligomer Formation by Alpha-Synuclein
M Iljina, AJ Dear, GA Garcia, S De, L Tosatto, P Flagmeier, DR Whiten, TCT Michaels, D Frenkel, CM Dobson, TPJ Knowles, D Klenerman
– ACS nano
(2018)
12,
10855
(doi: 10.1021/acsnano.8b03575)
Filamentous aggregates are fragmented by the proteasome holoenzyme
R Cliffe, J Sang, F Kundel, D Finley, D Klenerman, Y Ye
– Cell Reports
(2018)
467068
(doi: 10.1101/467068)
Sensitive light-sheet microscopy in multiwell plates using an AFM cantilever
A Ponjavic, Y Ye, E Laue, SF Lee, D Klenerman
– Biomedical Optics Express
(2018)
9,
5863
(doi: 10.1364/BOE.9.005863)
Characterisation of particle-surface interactions via anharmonic acoustic transduction
C da Silva Granja, N Sandström, I Efimov, VP Ostanin, W van der Wijngaart, D Klenerman, SK Ghosh
– Sensors and Actuators B: Chemical
(2018)
272,
175
(doi: 10.1016/j.snb.2018.05.016)
Automated Behavioral Analysis of Large C. Elegans Populations Using a Wide Field-of-view Tracking Platform
M Perni, S Casford, FA Aprile, EA Nollen, TPJ Knowles, M Vendruscolo, CM Dobson
– Journal of Visualized Experiments
(2018)
2018,
ARTN e58643
(doi: 10.3791/58643)
Statistical Mechanics of Globular Oligomer Formation by Protein Molecules.
AJ Dear, A Šarić, TCT Michaels, CM Dobson, TPJ Knowles
– Journal of Physical Chemistry B
(2018)
122,
11721
(doi: 10.1021/acs.jpcb.8b07805)
Picomolar concentrations of oligomeric alpha-synuclein sensitizes TLR4 to play an initiating role in Parkinson's disease pathogenesis (vol 137, pg 103, 2019)
CD Hughes, ML Choi, M Ryten, L Hopkins, A Drews, JA Botía, M Iljina, M Rodrigues, SA Gagliano, S Gandhi, C Bryant, D Klenerman
– Acta neuropathologica
(2018)
137,
121
(doi: 10.1007/s00401-018-1919-7)
Direct Observation of Murine Prion Protein Replication in Vitro.
JC Sang, G Meisl, AM Thackray, L Hong, A Ponjavic, TPJ Knowles, R Bujdoso, D Klenerman
– Journal of the American Chemical Society
(2018)
140,
14789
(doi: 10.1021/jacs.8b08311)
¬Nanoscopic characterization of individual endogenous protein aggregates in human neuronal cells
DR Whiten, Y Zuo, L Calo, M-L Choi, S De, P Flagmeier, DC Wirthensohn, F Kundel, RT Ranasinghe, SE Sanchez, D Athauda, SF Lee, CM Dobson, S Gandhi, M-G Spillantini, D Klenerman, MH Horrocks
– Chembiochem : a European journal of chemical biology
(2018)
19,
2033
(doi: 10.1002/cbic.201800209)
SAR by kinetics for drug discovery in protein misfolding diseases.
S Chia, J Habchi, TCT Michaels, SIA Cohen, S Linse, CM Dobson, TPJ Knowles, M Vendruscolo
– Proc Natl Acad Sci U S A
(2018)
115,
10245
(doi: 10.1073/pnas.1807884115)
Microfluidic deposition for resolving single-molecule protein architecture and heterogeneity.
FS Ruggeri, J Charmet, T Kartanas, Q Peter, S Chia, J Habchi, CM Dobson, M Vendruscolo, TPJ Knowles
– Nat Commun
(2018)
9,
3890
(doi: 10.1038/s41467-018-06345-4)
Solution Fibre Spinning Technique for the Fabrication of Tuneable Decellularised Matrix-Laden Fibres and Fibrous Micromembranes
Z Li, J Tuffin, IM Lei, FS Ruggeri, NS Lewis, EL Gill, T Savin, L Huleihel, SF Badylak, T Knowles, SC Satchell, GI Welsh, MA Saleem, YYS Huang
– Acta Biomaterialia
(2018)
78,
111
(doi: 10.1016/j.actbio.2018.08.010)
Extrinsic Amyloid-Binding Dyes for the Detection of Individual Protein Aggregates in Solution
D Klenerman
– Analytical chemistry
(2018)
90,
10385
(doi: 10.1021/acs.analchem.8b02226)
Identification of oxidative stress in red blood cells with nanoscale chemical resolution by infrared nanospectroscopy
FS Ruggeri, C Marcott, S Dinarelli, G Longo, M Girasole, G Dietler, TPJ Knowles
– International journal of molecular sciences
(2018)
19,
2582
(doi: 10.3390/ijms19092582)
DNA-Coated Functional Oil Droplets
A Caciagli, M Zupkauskas, A Levin, TPJ Knowles, C Mugemana, N Bruns, T O'Neill, WJ Frith, E Eiser
– Langmuir : the ACS journal of surfaces and colloids
(2018)
34,
10073
(doi: 10.1021/acs.langmuir.8b01828)
Self-Assembly-Mediated Release of Peptide Nanoparticles through Jets Across Microdroplet Interfaces.
A Levin, TCT Michaels, TO Mason, T Müller, L Adler-Abramovich, L Mahadevan, ME Cates, E Gazit, TPJ Knowles
– ACS Applied Materials and Interfaces
(2018)
10,
27578
(doi: 10.1021/acsami.8b09511)

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