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Professor of Supramolecular & Polymer Chemistry / Director of the Melville Laboratory for Polymer Synthesis

What we do

Our research interests include the synthesis of functional nanosystems, controlled polymer architectures and dynamic supramolecular assemblies through molecular recognition processes.

The underlying theme of our research lies at the interface between synthetic organic efforts on small molecules and macroscopic properties at the materials level, developing a macro-organic approach to chemistry. Dynamic supramolecular self-assembly of materials will be an area of great importance in the coming years, allowing for innovations in nanotechnology and at the biological and chemical interfaces.

We are particularly interested in exploring topics such as water-soluble and stimuli-responsive materials, template and imprinting technologies of functional polymers for use in chiral separations and enantioselective catalysis, and controlling material morphologies and architectures both in solution and in the solid state through rational design and a multi-step, hierarchical self-assembly process.

Watch Professor Scherman discuss his research

Take a tour of the Melville Lab


On-Resin Recognition of Aromatic Oligopeptides and Proteins through Host-Enhanced Heterodimerization
X Chen, Z Huang, RL Sala, AM McLean, G Wu, K Sokołowski, K King, JA McCune, OA Scherman
– J Am Chem Soc
Facile, Energy‐Efficient Microscale Fibrillation of Polyacrylamides under Ambient Conditions
MV Cruz, DU Shah, NC Warner, JA McCune, OA Scherman
– Advanced Materials
A Platform Approach to Protein Encapsulates with Controllable Surface Chemistry.
N Warner, IG Osojnik Črnivec, VK Rana, M Cruz, OA Scherman
– Molecules
SERSbot: Revealing the details of SERS multi-analyte sensing using full automation
D-B Grys, B de Nijs, J Huang, OA Scherman, JJ Baumberg
– ACS sensors
Highly compressible glass-like supramolecular polymer networks
Z Huang, X Chen, SJK O'Neill, G Wu, DJ Whitaker, J Li, JA McCune, OA Scherman
– Nat Mater
Introduction: Molecular Self-Assembly
D Pochan, O Scherman
– Chemical Reviews
Nanoparticle surfactants for kinetically-arrested photoactive assemblies to track light-induced electron transfer
K Sokołowski, J Huang, T Földes, JA McCune, DD Xu, B de Nijs, R Chikkaraddy, SM Collins, E Rosta, JJ Baumberg, OA Scherman
– Nat Nanotechnol
Mechanically matching the rheological properties of brain tissue for drug-delivery in human glioblastoma models
CC Parkins, JH McAbee, L Ruff, A Wendler, R Mair, RJ Gilbertson, C Watts, OA Scherman
– Biomaterials
Formulation of Metal–Organic Framework-Based Drug Carriers by Controlled Coordination of Methoxy PEG Phosphate: Boosting Colloidal Stability and Redispersibility
X Chen, Y Zhuang, N Rampal, R Hewitt, G Divitini, CA O'Keefe, X Liu, DJ Whitaker, JW Wills, R Jugdaohsingh, JJ Powell, H Yu, CP Grey, OA Scherman, D Fairen-Jimenez
– J Am Chem Soc
Host-Guest Induced Peptide Folding with Sequence-Specific Structural Chirality.
DE Clarke, G Wu, C Wu, OA Scherman
– Journal of the American Chemical Society
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Head of group

Research Interest Groups

Telephone number

01223 334372 (shared)

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