Research Associate
Helen started her postdoctoral position in the group of Prof Oren Scherman in December 2014.
Her work focuses on the characterisation of oligomers formed by the Alzhimer's disease associated peptide amyloid-beta, using a range of biophysical techniques and cell assays.
Prior to this postdoctoral position, Helen completed her PhD degree in Biochemistry at Queen Mary, University of London under the supervision of Dr John Viles.
Publications
Developing predictive rules for coordination geometry from visible circular dichroism of copper(II) and nickel(II) ions in histidine and amide main-chain complexes
– The FEBS journal
(2014)
281,
3945
(doi: 10.1111/febs.12934)
Copper(II) sequentially loads onto the N-terminal amino group of the cellular prion protein before the individual octarepeats
– Biochemistry
(2014)
53,
3934
(doi: 10.1021/bi500643b)
Human Serum Albumin Can Regulate Amyloid-β Peptide Fiber Growth in the Brain Interstitium IMPLICATIONS FOR ALZHEIMER DISEASE*
– J Biol Chem
(2012)
287,
28163
(doi: 10.1074/jbc.c112.360800)