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  • Currently displaying 881 - 900 of 1101 publications
Hydrodynamic trapping of molecules in lipid bilayers.
P Jönsson, J McColl, RW Clarke, VP Ostanin, B Jönsson, D Klenerman
– Proceedings of the National Academy of Sciences
(2012)
109,
10328
(doi: 10.1073/pnas.1202858109)
Selenium-enhanced electron microscopic imaging of different aggregate forms of a segment of the amyloid β peptide in cells
EK McGuire, M Motskin, B Bolognesi, SD Bergin, TPJ Knowles, J Skepper, LM Luheshi, DW McComb, CM Dobson, AE Porter
– ACS Nano
(2012)
6,
4740
(doi: 10.1021/nn204859e)
Direct observation of the interconversion of normal and toxic forms of α-synuclein
N Cremades, SIA Cohen, E Deas, AY Abramov, AY Chen, A Orte, M Sandal, RW Clarke, P Dunne, FA Aprile, CW Bertoncini, NW Wood, TPJ Knowles, CM Dobson, D Klenerman
– Cell
(2012)
149,
1048
(doi: 10.1016/j.cell.2012.03.037)
Topographical and electrochemical nanoscale imaging of living cells using voltage-switching mode scanning electrochemical microscopy.
Y Takahashi, AI Shevchuk, P Novak, B Babakinejad, J Macpherson, PR Unwin, H Shiku, J Gorelik, D Klenerman, YE Korchev, T Matsue
– Proc Natl Acad Sci U S A
(2012)
109,
11540
(doi: 10.1073/pnas.1203570109)
An alternative mechanism of clathrin-coated pit closure revealed by ion conductance microscopy
AI Shevchuk, P Novak, M Taylor, IA Diakonov, A Ziyadeh-Isleem, M Bitoun, P Guicheney, MJ Lab, J Gorelik, CJ Merrifield, D Klenerman, YE Korchev
– Journal of Cell Biology
(2012)
197,
499
(doi: 10.1083/jcb.201109130)
Role of elongation and secondary pathways in S6 amyloid fibril growth.
N Lorenzen, SIA Cohen, SB Nielsen, TW Herling, G Christiansen, CM Dobson, TPJ Knowles, D Otzen
– Biophys J
(2012)
102,
2167
(doi: 10.1016/j.bpj.2012.03.047)
Analyse der Energiebarrieren für das Wachstum von Amyloidfibrillen
AK Buell, A Dhulesia, DA White, TPJ Knowles, CM Dobson, ME Welland
– Angewandte Chemie
(2012)
124,
5339
(doi: 10.1002/ange.201108040)
Detailed analysis of the energy barriers for amyloid fibril growth
AK Buell, A Dhulesia, DA White, TPJ Knowles, CM Dobson, ME Welland
– Angewandte Chemie - International Edition
(2012)
51,
5247
(doi: 10.1002/anie.201108040)
From Macroscopic Measurements to Microscopic Mechanisms of Protein Aggregation
SIA Cohen, M Vendruscolo, CM Dobson, TPJ Knowles
– Journal of Molecular Biology
(2012)
421,
160
(doi: 10.1016/j.jmb.2012.02.031)
The extracellular chaperone clusterin sequesters oligomeric forms of the amyloid-β 1-40 peptide
P Narayan, A Orte, RW Clarke, B Bolognesi, S Hook, KA Ganzinger, S Meehan, MR Wilson, CM Dobson, D Klenerman
– Nature Structural and Molecular Biology
(2012)
19,
79
(doi: 10.1038/nsmb.2191)
Fluctuations in water, the hydrophobic effect and self-assembly
PS Varilly, AJ Patel, SN Jamadagni, H Acharya, MF Hagan, S Garde, D Chandler, TPJ Knowles, D Frenkel
– ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY
(2012)
244,
(link to publication)
Ubiquitin chain conformation regulates recognition and activity of interacting proteins
Y Ye, G Blaser, MH Horrocks, MJ Ruedas-Rama, S Ibrahim, AA Zhukov, A Orte, D Klenerman, SE Jackson, D Komander
– Nature (in press)
(2012)
492,
266
(doi: 10.1038/nature11722)
Single Molecule Fluorescence under Conditions of Fast Flow
MH Horrocks, H Li, J-U Shim, RT Ranasinghe, RW Clarke, WTS Huck, C Abell, D Klenerman
– Analytical chemistry
(2011)
84,
179
(doi: 10.1021/ac202313d)
Protein solubility and protein homeostasis: A generic view of protein misfolding disorders
M Vendruscolo, TPJ Knowles, CM Dobson
– Cold Spring Harbor Perspectives in Biology
(2011)
3,
(doi: 10.1101/cshperspect.a010454)
Three-dimensional superresolution colocalization of intracellular protein superstructures and the cell surface in live Caulobacter crescentus
MD Lew, SF Lee, JL Ptacin, MK Lee, RJ Twieg, L Shapiro, WE Moerner
– Proceedings of the National Academy of Sciences of the United States of America
(2011)
108,
e1102
(doi: 10.1073/pnas.1114444108)
Probing small molecule binding to amyloid fibrils.
AK Buell, EK Esbjörner, PJ Riss, DA White, FI Aigbirhio, G Toth, ME Welland, CM Dobson, TPJ Knowles
– Physical chemistry chemical physics : PCCP
(2011)
13,
20044
(doi: 10.1039/c1cp22283j)
Inversion of the balance between hydrophobic and hydrogen bonding interactions in protein folding and aggregation
AW Fitzpatrick, TPJ Knowles, CA Waudby, M Vendruscolo, CM Dobson
– PLoS computational biology
(2011)
7,
e1002169
(doi: 10.1371/journal.pcbi.1002169)
Binding of the molecular chaperone αB-crystallin to Aβ amyloid fibrils inhibits fibril elongation.
SL Shammas, CA Waudby, S Wang, AK Buell, TPJ Knowles, H Ecroyd, ME Welland, JA Carver, CM Dobson, S Meehan
– Biophys J
(2011)
101,
1681
(doi: 10.1016/j.bpj.2011.07.056)
Multifunctional nanoprobes for nanoscale chemical imaging and localized chemical delivery at surfaces and interfaces
Y Takahashi, AI Shevchuk, P Novak, Y Zhang, N Ebejer, JV MacPherson, PR Unwin, AJ Pollard, D Roy, CA Clifford, H Shiku, T Matsue, D Klenerman, YE Korchev
– Angewandte Chemie - International Edition
(2011)
50,
9638
(doi: 10.1002/anie.201102796)
Imaging and characterisation of the surface of live cells
D Klenerman, YE Korchev, SJ Davis
– Current Opinion in Chemical Biology
(2011)
15,
696
(doi: 10.1016/j.cbpa.2011.04.001)

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