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  • Currently displaying 81 - 100 of 1093 publications
Biomolecular condensates are characterized by interphase electric potentials
AE Posey, A Bremer, NA Erkamp, A Pant, TPJ Knowles, Y Dai, T Mittag, RV Pappu
(2024)
(doi: 10.1101/2024.07.02.601783)
α-Synuclein Oligomers Displace Monomeric α-Synuclein from Lipid Membranes.
G Šneiderienė, MA Czekalska, CK Xu, AK Jayaram, G Krainer, WE Arter, QAE Peter, M Castellana-Cruz, KL Saar, A Levin, T Mueller, S Fiedler, SRA Devenish, H Fiegler, JR Kumita, TPJ Knowles
– ACS Nano
(2024)
18,
17469
(doi: 10.1021/acsnano.3c10889)
Hierarchical Protofilament Intertwining Rules the Formation of Mixed-Curvature Amyloid Polymorphs.
J Zhou, S Assenza, M Tatli, J Tian, IM Ilie, EL Starostin, A Caflisch, TPJ Knowles, G Dietler, FS Ruggeri, H Stahlberg, SK Sekatskii, R Mezzenga
– Advanced science (Weinheim, Baden-Wurttemberg, Germany)
(2024)
11,
e2402740
(doi: 10.1002/advs.202402740)
The Cystic Fibrosis Transmembrane Regulator Controls Tolerogenic Responses to Food Allergens in Mice and Humans
M Emmenegger, C Zografou, Y Dai, L Hoyt, R Gudneppanavar, A Chincisan, H Rehrauer, F Noé, N Zajac, G Meisl, M Schneider, H Nguyen, K Höpker, T Knowles, M Sospedra, R Martin, A Ring, S Leeds, S Eisenbarth, M Egan, E Bruscia, A Aguzzi
(2024)
(doi: 10.1101/2024.06.17.24309019)
Electrolyte‐gated organic field‐effect transistors with high operational stability and lifetime in practical electrolytes
D Simatos, M Nikolka, J Charmet, LJ Spalek, Z Toprakcioglu, IE Jacobs, IB Dimov, G Schweicher, MJ Lee, CM Fernández‐Posada, DJ Howe, TA Hakala, LWY Roode, V Pecunia, TP Sharp, W Zhang, M Alsufyani, I McCulloch, TPJ Knowles, H Sirringhaus
– SmartMat
(2024)
5,
e1291
(doi: 10.1002/smm2.1291)
The role of shear forces in primary and secondary nucleation of amyloid fibrils.
E Axell, J Hu, M Lindberg, AJ Dear, L Ortigosa-Pascual, EA Andrzejewska, G Šneiderienė, D Thacker, TPJ Knowles, E Sparr, S Linse
– Proc Natl Acad Sci U S A
(2024)
121,
e2322572121
(doi: 10.1073/pnas.2322572121)
Electrolyte‐gated organic field‐effect transistors with high operational stability and lifetime in practical electrolytes
D Simatos, M Nikolka, J Charmet, LJ Spalek, Z Toprakcioglu, IE Jacobs, IB Dimov, G Schweicher, MJ Lee, CM Fernández-Posada, DJ Howe, TA Hakala, LWY Roode, V Pecunia, TP Sharp, W Zhang, M Alsufyani, I McCulloch, TPJ Knowles, H Sirringhaus
– SmartMat
(2024)
5,
(doi: 10.1002/smm2.1291)
The delayed kinetics of Myddosome formation explains why amyloid-beta aggregates trigger Toll-like receptor 4 less efficiently than lipopolysaccharide.
B Li, P Suresh, J Brelstaff, S Kedia, CE Bryant, D Klenerman
(2024)
(doi: 10.7554/eLife.92350)
The delayed kinetics of Myddosome formation explains why amyloid-beta aggregates trigger Toll-like receptor 4 less efficiently than lipopolysaccharide
B Li, P Suresh, J Brelstaff, S Kedia, CE Bryant, D Klenerman
– eLife
(2024)
13,
(doi: 10.7554/elife.92350.3)
Biomolecular condensates with complex architectures via controlled nucleation
NA Erkamp, MAM Verwiel, D Qian, T Sneideris, FA Spaepen, DA Weitz, JCM van Hest, TPJ Knowles
– Nature Chemical Engineering
(2024)
1,
430
(doi: 10.1038/s44286-024-00077-7)
Co-aggregation with Apolipoprotein E modulates the function of Amyloid-β in Alzheimer’s disease
Z Xia, EE Prescott, A Urbanek, HE Wareing, MC King, A Olerinyova, H Dakin, T Leah, KA Barnes, MM Matuszyk, E Dimou, E Hidari, YP Zhang, JYL Lam, JSH Danial, MR Strickland, H Jiang, P Thornton, DC Crowther, S Ohtonen, M Gómez-Budia, SM Bell, L Ferraiuolo, H Mortiboys, A Higginbottom, SB Wharton, DM Holtzman, T Malm, RT Ranasinghe, D Klenerman, S De
– Nature communications
(2024)
15,
4695
(doi: 10.1038/s41467-024-49028-z)
Aβ Oligomer Dissociation Is Catalyzed by Fibril Surfaces.
A Dear, D Thacker, S Wennmalm, L Ortigosa-Pascual, EA Andrzejewska, G Meisl, S Linse, T Knowles
– ACS chemical neuroscience
(2024)
15,
2296
(doi: 10.1021/acschemneuro.4c00127)
Solutes unmask differences in clustering versus phase separation of FET proteins.
M Kar, LT Vogel, G Chauhan, S Felekyan, H Ausserwöger, TJ Welsh, F Dar, AR Kamath, TPJ Knowles, AA Hyman, CAM Seidel, RV Pappu
– Nat Commun
(2024)
15,
4408
(doi: 10.1038/s41467-024-48775-3)
An evolutionarily conserved mechanism controls reversible amyloids of pyruvate kinase via pH-sensing regions
G Cereghetti, VM Kissling, LM Koch, A Arm, CC Schmidt, Y Thüringer, N Zamboni, P Afanasyev, M Linsenmeier, C Eichmann, S Kroschwald, J Zhou, Y Cao, DM Pfizenmaier, T Wiegand, R Cadalbert, G Gupta, D Boehringer, TPJ Knowles, R Mezzenga, P Arosio, R Riek, M Peter
– Developmental cell
(2024)
59,
1876
(doi: 10.1016/j.devcel.2024.04.018)
Biomolecular condensates sustain pH gradients at equilibrium driven by charge neutralisation
H Ausserwöger, R Scrutton, T Sneideris, C Fischer, D Qian, E de Csilléry, K Saar, A Białek, M Oeller, G Krainer, T Franzmann, S Wittmann, J Iglesias-Artola, G Invernizzi, A Hyman, S Alberti, N Lorenzen, T Knowles
(2024)
(doi: 10.1101/2024.05.23.595321)
Polysaccharide functionalization reduces lipid vesicle stiffness.
K Jahnke, M Pavlovic, W Xu, A Chen, TPJ Knowles, LR Arriaga, DA Weitz
– Proc Natl Acad Sci U S A
(2024)
121,
e2317227121
(doi: 10.1073/pnas.2317227121)
Single-molecule characterization of salivary protein aggregates from Parkinson’s disease patients: a pilot study
M Furlepa, YP Zhang, E Lobanova, L Kahanawita, G Vivacqua, CH Williams-Gray, D Klenerman
– Brain Communications
(2024)
6,
fcae178
(doi: 10.1093/braincomms/fcae178)
Single-Molecule Stoichiometry of Supramolecular Complexes
A McLean, RL Sala, BW Longbottom, AR Carr, JA McCune, SF Lee, OA Scherman
– J Am Chem Soc
(2024)
146,
12877
(doi: 10.1021/jacs.4c00611)
Kinetic models reveal the interplay of protein production and aggregation
J Wei, G Meisl, A Dear, M Oosterhuis, R Melki, C Emanuelsson, S Linse, TPJ Knowles
– Chemical science
(2024)
15,
8430
(doi: 10.1039/d4sc00088a)
Pharmacological inhibition of α-synuclein aggregation within liquid condensates
ST Dada, Z Toprakcioglu, MP Cali, A Röntgen, MC Hardenberg, OM Morris, LK Mrugalla, TPJ Knowles, M Vendruscolo
– Nature Communications
(2024)
15,
3835
(doi: 10.1038/s41467-024-47585-x)

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