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Centre for Experimental Biophysical Chemistry

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  • Currently displaying 641 - 660 of 1101 publications
Systematic development of small molecules to inhibit specific microscopic steps of Aβ42 aggregation in Alzheimer's disease.
J Habchi, S Chia, R Limbocker, B Mannini, M Ahn, M Perni, O Hansson, P Arosio, JR Kumita, PK Challa, SIA Cohen, S Linse, CM Dobson, TPJ Knowles, M Vendruscolo
– Proceedings of the National Academy of Sciences
(2016)
114,
E200
Monitoring Ca2+ elevations in individual astrocytes upon local release of amyloid beta in acute brain slices.
O Tyurikova, K Zheng, A Rings, A Drews, D Klenerman, DA Rusakov
– Brain research bulletin
(2016)
136,
85
pyFRET: A Python Library for Single Molecule Fluorescence Data Analysis
RR Murphy, SE Jackson, D Klenerman
– Proceedings of the 7th European Conference on Python in Science (EuroSciPy 2014)
(2016)
1412,
59
Multi-dimensional super-resolution imaging enables surface hydrophobicity mapping.
MN Bongiovanni, J Godet, MH Horrocks, L Tosatto, AR Carr, DC Wirthensohn, RT Ranasinghe, JV Fritz, CM Dobson, D Klenerman, SF Lee
– Nat Commun
(2016)
7,
13544
Kinetics of spontaneous filament nucleation via oligomers: Insights from theory and simulation
A Šarić, TCT Michaels, A Zaccone, TPJ Knowles, D Frenkel
– Journal of Chemical Physics
(2016)
145,
211926
A randomized control trial evaluating fluorescent ink $\textit{versus}$ dark ink tattoos for breast radiotherapy
SJ Landeg, AM Kirby, SF Lee, F Bartlett, K Titmarsh, E Donovan, CL Griffin, L Gothard, I Locke, HA McNair
– The British Journal of Radiology
(2016)
89,
20160288
Micro- and nanoscale hierarchical structure of core-shell protein microgels.
LR Volpatti, U Shimanovich, FS Ruggeri, S Bolisetty, T Müller, TO Mason, TCT Michaels, R Mezzenga, G Dietler, TPJ Knowles
– Journal of materials chemistry. B
(2016)
4,
7989
Dynamics of heteromolecular filament formation
AJ Dear, TCT Michaels, TPJ Knowles
– J Chem Phys
(2016)
145,
175101
β-Synuclein suppresses both the initiation and amplification steps of α-synuclein aggregation via competitive binding to surfaces.
JWP Brown, AK Buell, TCT Michaels, G Meisl, J Carozza, P Flagmeier, M Vendruscolo, TPJ Knowles, CM Dobson, C Galvagnion
– Scientific Reports
(2016)
6,
36010
Dynamic microfluidic control of supramolecular peptide self-assembly.
ZA Arnon, A Vitalis, A Levin, TCT Michaels, A Caflisch, TPJ Knowles, L Adler-Abramovich, E Gazit
– Nature communications
(2016)
7,
13190
Scaling and dimensionality in the chemical kinetics of protein filament formation
TCT Michaels, AJ Dear, TPJ Knowles
– International Reviews in Physical Chemistry
(2016)
35,
679
Low Stress Ion Conductance Microscopy of Sub-Cellular Stiffness
RW Clarke, P Novak, A Zhukov, EJ Tyler, M Cano-Jaimez, A Drews, O Richards, K Volynski, C Bishop, D Klenerman
– Soft matter
(2016)
12,
7953
Fabrication of fibrillosomes from droplets stabilized by protein nanofibrils at all-aqueous interfaces.
Y Song, U Shimanovich, TCT Michaels, Q Ma, J Li, TPJ Knowles, HC Shum
– Nature communications
(2016)
7,
12934
Kinetics of spontaneous filament nucleation via oligomers: insights from theory and simulation
A Šarić, TCT Michaels, A Zaccone, TPJ Knowles, D Frenkel
(2016)
Elastic instability-mediated actuation by a supra-molecular polymer
A Levin, TCT Michaels, L Adler-Abramovich, TO Mason, T Müller, B Zhang, L Mahadevan, E Gazit, TPJ Knowles
– Nature Physics
(2016)
12,
926
Intra-chain organisation of hydrophobic residues controls inter-chain aggregation rates of amphiphilic polymers
P Varilly, AP Willard, JB Kirkegaard, TPJ Knowles, D Chandler
(2016)
Arachidonic acid mediates the formation of abundant alpha-helical multimers of alpha-synuclein
M Iljina, L Tosatto, ML Choi, JC Sang, Y Ye, CD Hughes, CE Bryant, S Gandhi, D Klenerman
– Sci Rep
(2016)
6,
33928
Nanoscopic Cellular Imaging: Confinement Broadens Understanding.
SA Lee, A Ponjavic, C Siv, SF Lee, JS Biteen
– ACS Nano
(2016)
10,
8143
Kinetics of fragmentation and dissociation of two-strand protein filaments: Coarse-grained simulations and experiments
A Zaccone, I Terentjev, TW Herling, TPJ Knowles, A Aleksandrova, EM Terentjev
(2016)
Kinetics of fragmentation and dissociation of two-strand protein filaments: Coarse-grained simulations and experiments.
A Zaccone, I Terentjev, TW Herling, TPJ Knowles, A Aleksandrova, EM Terentjev
– J Chem Phys
(2016)
145,
105101