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Centre for Experimental Biophysical Chemistry

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  • Currently displaying 621 - 640 of 1101 publications
Acceleration of α-synuclein aggregation.
R Gaspar, G Meisl, AK Buell, L Young, CF Kaminski, TPJ Knowles, E Sparr, S Linse
– Amyloid
(2017)
24,
20
A natural product inhibits the initiation of α-synuclein aggregation & suppresses its toxicity
M Perni, C Galvagnion, A Maltsev, G Meisl, MBD Müller, PK Challa, JB Kirkegaard, P Flagmeier, SIA Cohen, R Cascella, SW Chen, R Limboker, P Sormanni, GT Heller, FA Aprile, N Cremades, C Cecchi, F Chiti, EAA Nollen, TPJ Knowles, M Vendruscolo, A Bax, M Zasloff, CM Dobson
– Proceedings of the National Academy of Sciences
(2017)
114,
E1009
Physical principles of filamentous protein self-assembly kinetics.
TCT Michaels, LX Liu, G Meisl, TPJ Knowles
– Journal of Physics Condensed Matter
(2017)
29,
153002
Attenuating the Toxicity of Amyloid-Beta Aggregation with Specific Species
R Limbocker, B Mannini, M Perni, S Chia, G Heller, FS Ruggeri, J Habchi, G Meisl, PK Challa, M Zasloff, TPJ Knowles, M Vendruscolo, CM Dobson
– Biophysical Journal
(2017)
112,
494a
Direct Modulation of the Mitochondrial Permeability Transition Pore by Oligomeric Alpha-Synuclein Causes Toxicity in PD
M Ludtmann, P Angelova, M-L Choi, M Horrocks, A Baev, D Little, M Devine, P Gissen, E Pavlov, D Klenerman, A Abramov, S Gandhi
– Biophysical Journal
(2017)
112,
440a
On-chip label-free protein analysis with downstream electrodes for direct removal of electrolysis products
KL Saar, Y Zhang, T Müller, CP Kumar, S Devenish, A Lynn, U Łapińska, X Yang, S Linse, TPJ Knowles
– Lab Chip
(2017)
18,
162
Secondary nucleation of monomers on fibril surface dominates $\alpha$-synuclein aggregation and provides autocatalytic amyloid amplification
R Gaspar, G Meisl, AK Buell, L Young, CF Kaminski, TPJ Knowles, E Sparr, S Linse
– Q Rev Biophys
(2017)
50,
e6
Microfluidic devices fabricated using fast wafer-scale LED-lithography patterning
PK Challa, T Kartanas, J Charmet, TPJ Knowles
– Biomicrofluidics
(2017)
11,
014113
Evidence for self-replication of Alzheimer-associated Aβ42 amyloid along the sides of fibrils
M Tornquist, R Cukalevski, U Weininger, G Meisl, TPJ Knowles, T Leiding, M Akke, S Linse
– EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
(2017)
46,
S242
Ultrasensitive measurement of Ca2+ influx into lipid vesicles induced by protein aggregates
P Flagmeier, S De, DC Wirthensohn, SF Lee, C Vincke, S Muyldermans, TP Knowles, S Gandhi, CM Dobson, D Klenerman
– EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
(2017)
46,
S237
Measuring the prion-like character of tau by TIRF microscopy
F Kundel, B Falcon, L Hong, N Esteras, AJ Dear, AY Abramov, TPJ Knowles, M Goedert, D Klenerman
– EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
(2017)
46,
S240
DNA PAINTing amyloid aggregates
MH Horrocks, D Whiten, Y Zuo, L Calo, MG Spillantini, S Gandhi, D Klenerman
– EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
(2017)
46,
S236
Kinetics of protein aggregation
T Knowles
– FEBS JOURNAL
(2017)
284,
34
Imaging the early events of T-cell triggering
D Klenerman
– EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
(2017)
46,
S108
Single α-synuclein oligomers are hydrophobically distinct from mature fibrils
J-E Lee, MN Bongiovanni, M Rodrigues, CM Dobson, SF Lee, D Klenerman
– EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
(2017)
46,
S348
A microfluidic platform for quantitative protein studies
TW Herling, P Arosio, T Mueller, DJ O'Connell, MC Bauer, J Persson, U Weininger, S Linse, TPJ Knowles
– EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
(2017)
46,
S345
DNA PAINTing amyloid aggregates
MH Horrocks, D Whiten, Y Zuo, L Calo, MG Spillantini, S Gandhi, D Klenerman
– EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
(2017)
46,
S68
Size dependent structure and effects of amyloid beta42
D Wirthensohn, F Kundel, S De, C Hughes, MH Horrocks, P Flagmeier, D Klenerman
– EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
(2017)
46,
S242
Non-perturbative single-molecule imaging of tau aggregates by genetic code expansion
F Kundel, MH Horrocks, Y Ye, D Klenerman
– EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
(2017)
46,
S240
Single amyloid aggregates chemical and structural analysis by infrared nanospectroscopy
FS Ruggeri, J Habchi, C Sean, M Vendruscolo, TPJ Knowles
– EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
(2017)
46,
S370